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1FVK	THE 1.7 ANGSTROM STRUCTURE OF WILD TYPE DISULFIDE BOND FORMATION PROTEIN (DSBA) Descriptor: DISULFIDE BOND FORMATION PROTEIN Authors: Martin, J.L, Guddat, L.W. Deposit date: 1996-08-28 Release date: 1997-08-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
5VYO	The complex structure of Burkholderia pseudomallei DsbA bound to a peptide Descriptor: Disulfide bond formation protein B, Thiol:disulfide interchange protein Authors: McMahon, R.M, Martin, J.L. Deposit date: 2017-05-25 Release date: 2018-03-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB. Infect. Immun., 86, 2018
4GXZ	Crystal structure of a periplasmic thioredoxin-like protein from Salmonella enterica serovar Typhimurium Descriptor: Suppression of copper sensitivity protein Authors: Shepherd, M, Heras, B, King, G.J, Argente, M.P, Achard, M.E.S, King, N.P, McEwan, A.G, Schembri, M.A. Deposit date: 2012-09-04 Release date: 2013-07-17 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural and functional characterization of ScsC, a periplasmic thioredoxin-like protein from Salmonella enterica serovar Typhimurium Antioxid Redox Signal, 19, 2013
1BED	STRUCTURE OF DISULFIDE OXIDOREDUCTASE Descriptor: DSBA OXIDOREDUCTASE Authors: Hu, S.-H, Martin, J.L. Deposit date: 1996-09-16 Release date: 1997-10-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae. J.Mol.Biol., 268, 1997
1YZX	Crystal structure of human kappa class glutathione transferase Descriptor: Glutathione S-transferase kappa 1, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE Authors: Li, J, Xia, Z, Ding, J. Deposit date: 2005-02-28 Release date: 2005-11-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology and structure similarity to the theta class enzyme PROTEIN SCI., 14, 2005
1BQ7	DSBA MUTANT P151A, ROLE OF THE CIS-PROLINE IN THE ACTIVE SITE OF DSBA Descriptor: PROTEIN (DISULFIDE OXIDOREDUCTASE) Authors: Charbonnier, J.-B, Stura, E.A. Deposit date: 1998-08-21 Release date: 1999-08-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: On the role of the cis-proline residue in the active site of DsbA. Protein Sci., 8, 1999
4OCF	Crystal structure of the disulfide oxidoreductase DsbA (S30XXC33) active site mutant from Proteus mirabilis Descriptor: THIOCYANATE ION, Thiol:disulfide interchange protein Authors: Kurth, F, Martin, J.L. Deposit date: 2014-01-09 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.979 Å) Cite: Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
4OCE	Crystal structure of the disulfide oxidoreductase DsbA from Proteus mirabilis Descriptor: MALONATE ION, Thiol:disulfide interchange protein Authors: Kurth, F, Martin, J.L. Deposit date: 2014-01-09 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.768 Å) Cite: Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
3L9U	Crystal Structure of Salmonella enterica serovar Typhimurium DsbL Descriptor: Disulfide isomerase Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.568 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
3L9V	Crystal Structure of Salmonella enterica serovar Typhimurium SrgA Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
2B6M	Structure of the DsbA mutant (P31A-C33A) Descriptor: DI(HYDROXYETHYL)ETHER, Thiol:disulfide interchange protein dsbA Authors: Vives, C, Royant, A, Serre, L. Deposit date: 2005-10-03 Release date: 2006-10-17 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of the DsbA mutant To be Published
2B3S	structure of the DSBA mutant (P31G-C33A) Descriptor: Thiol:disulfide interchange protein dsbA Authors: Vives, C, Royant, A, Serre, L. Deposit date: 2005-09-21 Release date: 2006-09-05 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structure of the DSBA mutant (P31G-C33A) To be Published
3L9S	Crystal Structure of Salmonella enterica serovar Typhimurium DsbA Descriptor: Thiol:disulfide interchange protein Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
4OD7	Complex structure of Proteus mirablis DsbA (C30S) with a non-covalently bound peptide PWATCDS Descriptor: (ACE)PWATCDS(NH2) Peptide, THIOCYANATE ION, Thiol:disulfide interchange protein Authors: Kurth, F, Premkumar, L, Martin, J.L. Deposit date: 2014-01-10 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.597 Å) Cite: Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
1DSB	CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO Descriptor: DSBA Authors: Martin, J.L, Bardwell, J.C.A, Kuriyan, J. Deposit date: 1993-05-24 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365, 1993
1UN2	Crystal structure of circularly permuted CPDSBA_Q100T99: Preserved Global Fold and Local Structural Adjustments Descriptor: THIOL-DISULFIDE INTERCHANGE PROTEIN Authors: Manjasetty, B.A, Hennecke, J, Glockshuber, R, Heinemann, U. Deposit date: 2003-09-03 Release date: 2003-09-26 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of Circularly Permuted Dsba(Q100T99): Preserved Global Fold and Local Structural Adjustments Acta Crystallogr.,Sect.D, 60, 2004
1TI1	crystal structure of a mutant DsbA Descriptor: DODECANE, Thiol:disulfide interchange protein dsbA Authors: Kone, A, Serre, L. Deposit date: 2004-06-02 Release date: 2005-05-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant. J.Mol.Biol., 347, 2005
1U3A	mutant DsbA Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Thiol: disulfide interchange protein dsbA Authors: Serre, L. Deposit date: 2004-07-21 Release date: 2005-05-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant J.Mol.Biol., 347, 2005
4WET	Crystal structure of E.Coli DsbA in complex with compound 16 Descriptor: 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-tyrosine, SODIUM ION, ... Authors: Ilyichova, O.V, Scanlon, M.J. Deposit date: 2014-09-11 Release date: 2015-01-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
4WF5	Crystal structure of E.Coli DsbA soaked with compound 4 Descriptor: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ... Authors: Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. Deposit date: 2014-09-12 Release date: 2015-01-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
4WEY	Crystal structure of E.Coli DsbA in complex with compound 17 Descriptor: 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine, Thiol:disulfide interchange protein Authors: Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. Deposit date: 2014-09-11 Release date: 2015-01-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
6XSP	Crystal structure of E.coli DsbA in complex with 2-(2,6-bis(3-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [2,6-bis(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-15 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XSQ	Crystal structure of E.coli DsbA in complex with 2-(6-(3-methoxyphenyl)-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-16 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XT3	Crystal structure of E.coli DsbA in complex with 3-(3-(carboxymethyl)-6-(3-methoxyphenyl)benzofuran-2-yl)benzoic acid Descriptor: 3-[3-(carboxymethyl)-6-(3-methoxyphenyl)-1-benzofuran-2-yl]benzoic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2020-07-17 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
4WF4	Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4 Descriptor: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, Thiol:disulfide interchange protein Authors: Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. Deposit date: 2014-09-12 Release date: 2015-01-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015

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