6BR4

Crystal structure of Escherichia coli DsbA in complex with {N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine

Summary for 6BR4

• Entry DOI: 10.2210/pdb6br4/pdb
• Related: 4wf5
• Descriptor: Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine, COPPER (II) ION, ... (4 entities in total)
• Functional Keywords: disulphide catalysts, thiol oxidase, virulence factor foldase, oxidoreductase
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 42640.44

Authors

Heras, B.,Totsika, M.,Paxman, J.J.,Wang, G.,Scanlon, M.J.,Martin, J.L. (deposition date: 2017-11-29, release date: 2017-12-27, Last modification date: 2020-01-01)

• Primary citation: Totsika, M.,Vagenas, D.,Paxman, J.J.,Wang, G.,Dhouib, R.,Sharma, P.,Martin, J.L.,Scanlon, M.J.,Heras, B.; Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens.; Antioxid. Redox Signal., 29:653-666, 2018; PubMed: 29237285; DOI: 10.1089/ars.2017.7104

Experimental method

X-RAY DIFFRACTION (1.99 Å)