PDB: 248 resultsInfo pagesStatus searchChemie searchBIRD

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1RAJ	Poliovirus Polymerase with a 68 residue N-terminal truncation Descriptor: Genome polyprotein Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2003-10-31 Release date: 2004-08-17 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase. Embo J., 23, 2004
3BSN	Norwalk Virus polymerase bound to 5-nitrocytidine triphosphate and primer-template RNA Descriptor: 5-nitrocytidine 5'-(tetrahydrogen triphosphate), GLYCEROL, MANGANESE (II) ION, ... Authors: Zamyatkin, D.F, Ng, K.K.S. Deposit date: 2007-12-26 Release date: 2008-01-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase. J.Biol.Chem., 283, 2008
3BSO	Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA Descriptor: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... Authors: Zamyatkin, D.F, Ng, K.K.S. Deposit date: 2007-12-26 Release date: 2008-01-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase. J.Biol.Chem., 283, 2008
4Y2A	Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor Descriptor: 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... Authors: Vives-Adrian, L, Ferrer-Orta, C, Verdaguer, N. Deposit date: 2015-02-09 Release date: 2015-04-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
1HI0	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex Descriptor: DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. Deposit date: 2000-12-31 Release date: 2001-03-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3 Å) Cite: A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
4Y34	Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 Descriptor: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... Authors: Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. Deposit date: 2015-02-10 Release date: 2015-04-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
4Y3C	I304V 3D polymerase mutant of EMCV Descriptor: 3D polymerase, CHLORIDE ION, GLYCEROL Authors: Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L. Deposit date: 2015-02-10 Release date: 2015-04-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
1XR5	Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14 Descriptor: Genome polyprotein, SAMARIUM (III) ION Authors: Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. Deposit date: 2004-10-13 Release date: 2004-10-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
1KHW	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. Deposit date: 2001-12-01 Release date: 2002-01-16 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
2UUW	2.75 angstrom structure of the D347G D348G mutant structure of Sapporo Virus RdRp Polymerase Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Fullerton, S, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J. Deposit date: 2007-03-07 Release date: 2007-05-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.76 Å) Cite: The 2.76 Angstrom Resolution Structure of the D347G D348G Mutant Structure of Sapporo Virus Rdrp Polymerase To be Published
3SFU	crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ... Authors: Kim, K.H, Alam, I. Deposit date: 2011-06-14 Release date: 2012-05-09 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
5F8M	Enterovirus 71 Polymerase Elongation Complex (C3S4/5 Form) Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
1KHV	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ Descriptor: LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE Authors: Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. Deposit date: 2001-12-01 Release date: 2002-01-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
1XR6	Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B Descriptor: Genome polyprotein, POTASSIUM ION Authors: Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. Deposit date: 2004-10-13 Release date: 2004-10-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
1XR7	Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16 Descriptor: Genome polyprotein Authors: Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A. Deposit date: 2004-10-13 Release date: 2004-10-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12, 2004
5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
3QID	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase Descriptor: GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ... Authors: Kim, K.H, Intekhab, A, Lee, J.H. Deposit date: 2011-01-27 Release date: 2011-12-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J.Gen.Virol., 92, 2011
2WK4	Dimeric structure of D347G D348G mutant of the sapporovirus RNA dependent RNA polymerase Descriptor: GLYCEROL, PROTEASE-POLYMERASE P70 Authors: Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P.A, Rohayem, J. Deposit date: 2009-06-05 Release date: 2010-09-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Dimeric Structure of D347G D348G Mutant of the Sapporovirus Sapporovirus RNA Dependent RNA Polymerase To be Published
5I61	Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
2UUT	The 2.4 angstrom resolution structure of the D346G mutant of the Sapporo Virus RdRp polymerase Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J. Deposit date: 2007-03-07 Release date: 2007-05-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The 2.4 Angstrom Resolution Structure of the D346G Mutant of the Sapporo Virus Rdrp Polymerase To be Published
3SFG	crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU) Descriptor: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ... Authors: Kim, K.H, Alam, I. Deposit date: 2011-06-13 Release date: 2012-05-09 Method: X-RAY DIFFRACTION (2.209 Å) Cite: Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
6KWR	Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form) Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (31-MER), ... Authors: Shi, W, Gong, P. Deposit date: 2019-09-08 Release date: 2019-12-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Res., 48, 2020
6KWQ	Crystal structure of enterovirus 71 polymerase elongation complex (native form) Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ... Authors: Shi, W, Gong, P. Deposit date: 2019-09-08 Release date: 2019-12-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Res., 48, 2020
6L4R	Crystal structure of Enterovirus D68 RdRp Descriptor: RdRp Authors: Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D. Deposit date: 2019-10-21 Release date: 2020-06-10 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.147 Å) Cite: Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 211, 2020
5Y6Z	Crystal structure of the coxsackievirus A16 polymerase elongation complex Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... Authors: Bi, P, Shu, B, Gong, P. Deposit date: 2017-08-15 Release date: 2017-12-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics Virol Sin, 32, 2017

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