PDB: 217 resultsInfo pagesStatus searchChemie searchBIRD

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5W4T	Crystal Structure of Fish Cadherin-23 EC1-3 Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... Authors: De-la-Torre, P, Sotomayor, M. Deposit date: 2017-06-12 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26, 2018
5VT8	Crystal Structure of Mouse Cadherin-23 EC24-25 Descriptor: CALCIUM ION, Cadherin-23 Authors: Jaiganesh, A, Sotomayor, M. Deposit date: 2017-05-15 Release date: 2018-05-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26, 2018
7CME	Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) Descriptor: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... Authors: Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. Deposit date: 2020-07-27 Release date: 2021-09-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
7CMF	Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) Descriptor: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3 Authors: Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. Deposit date: 2020-07-27 Release date: 2021-09-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
8D40	Crystal structure of human CELSR1 EC1-4 Descriptor: CALCIUM ION, Cadherin EGF LAG seven-pass G-type receptor 1, SODIUM ION Authors: Tamilselvan, E, Sotomayor, M. Deposit date: 2022-06-01 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (3.554 Å) Cite: Crystal structure of human CELSR1 EC1-4 to be published
8EGX	Complex of Fat4(EC1-4) bound to Dchs1(EC1-4) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Medina, E, Luca, V.C. Deposit date: 2022-09-13 Release date: 2023-02-22 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.688 Å) Cite: Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
8EGW	Complex of Fat4(EC1-4) bound to Dchs1(EC1-3) Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Medina, E, Luca, V.C. Deposit date: 2022-09-13 Release date: 2023-02-22 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the planar cell polarity cadherins Fat4 and Dachsous1. Nat Commun, 14, 2023
7EV1	Crystal structure of LI-Cadherin EC1-2 Descriptor: ACETATE ION, CALCIUM ION, Cadherin-17, ... Authors: Caaveiro, J.M.M, Yui, A, Tsumoto, K. Deposit date: 2021-05-19 Release date: 2021-06-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Mechanism of dimerization and structural features of human LI-cadherin. J.Biol.Chem., 297, 2021
7CYM	Crystal structure of LI-Cadherin EC1-4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Caaveiro, J.M.M, Yui, A, Tsumoto, K. Deposit date: 2020-09-03 Release date: 2021-08-18 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Mechanism of dimerization and structural features of human LI-cadherin. J.Biol.Chem., 297, 2021
2YST	Solution structure of the third cadherin domain from human protocadherin 7 Descriptor: Protocadherin-7 Authors: Seimiya, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2007-04-03 Release date: 2007-10-09 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of the third cadherin domain from human protocadherin 7 To be Published
2WCP	CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 Descriptor: CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... Authors: Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. Deposit date: 2009-03-13 Release date: 2010-04-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
2WHV	CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 (ALL CATION BINDING SITES OCCUPIED BY CALCIUM) Descriptor: CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... Authors: Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. Deposit date: 2009-05-07 Release date: 2010-04-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
4NUP	Crystal structure of mouse N-cadherin EC1-2 with AA insertion between residues 2 and 3 Descriptor: CALCIUM ION, N-CADHERIN EC1-2 Authors: Jin, X. Deposit date: 2013-12-03 Release date: 2014-09-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
1ZXK	Crystal Structure of Cadherin8 EC1 domain Descriptor: Cadherin-8 Authors: Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Arkus, N, Schieren, I, Rajebhosale, M, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. Deposit date: 2005-06-08 Release date: 2006-04-25 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.), 124, 2006
4NUM	Crystal structure of mouse N-cadherin EC1-2 A78SI92M Descriptor: CALCIUM ION, Cadherin-2 Authors: Jin, X. Deposit date: 2013-12-03 Release date: 2014-09-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
4OY9	Crystal structure of human P-Cadherin EC1-EC2 in closed conformation Descriptor: CALCIUM ION, Cadherin-3 Authors: Dalle Vedove, A, Lucarelli, A.P, Nardone, V, Matino, A, Parisini, E. Deposit date: 2014-02-11 Release date: 2015-04-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.62 Å) Cite: The X-ray structure of human P-cadherin EC1-EC2 in a closed conformation provides insight into the type I cadherin dimerization pathway. Acta Crystallogr.,Sect.F, 71, 2015
2WD0	CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2 Descriptor: CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... Authors: Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. Deposit date: 2009-03-18 Release date: 2010-04-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
2A4C	Crystal structure of mouse cadherin-11 EC1 Descriptor: Cadherin-11 Authors: Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Schieren, I, Rajebhosale, M, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. Deposit date: 2005-06-28 Release date: 2006-04-25 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.), 124, 2006
2A62	Crystal structure of mouse cadherin-8 EC1-3 Descriptor: CALCIUM ION, Cadherin-8 Authors: Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Arkus, N, Schieren, I, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. Deposit date: 2005-07-01 Release date: 2006-04-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (4.5 Å) Cite: Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.), 124, 2006
6E8F	Crystal Structure of Human Protocadherin-15 EC3-5 CD2-1 Descriptor: CALCIUM ION, Protocadherin-15, SODIUM ION Authors: Choudhary, D, Tamilselvan, E, Sotomayor, M. Deposit date: 2018-07-29 Release date: 2019-07-31 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc.Natl.Acad.Sci.USA, 2020
6EB5	Crystal Structure of Human Protocadherin-15 EC2-3 V250N Descriptor: CALCIUM ION, Protocadherin-15 Authors: Choudhary, D, Sotomayor, M. Deposit date: 2018-08-04 Release date: 2019-08-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc.Natl.Acad.Sci.USA, 2020
1ZVN	Crystal structure of chick MN-cadherin EC1 Descriptor: Cadherin 1 Authors: Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Schieren, I, Rajebhosale, M, Jessell, T.M, Honig, B, Shapiro, L, Price, S.R. Deposit date: 2005-06-02 Release date: 2006-04-25 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.), 124, 2006
4NUQ	Crystal structure of mouse N-cadherin EC1-2 W2F Descriptor: CALCIUM ION, Cadherin-2 Authors: Jin, X. Deposit date: 2013-12-03 Release date: 2014-09-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.116 Å) Cite: Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
2A4E	Crystal structure of mouse cadherin-11 EC1-2 Descriptor: CALCIUM ION, Cadherin-11 Authors: Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Arkus, N, Rajebhosale, M, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. Deposit date: 2005-06-28 Release date: 2006-04-25 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Type II cadherin ectodomain structures: implications for classical cadherin specificity. Cell(Cambridge,Mass.), 124, 2006
4NQQ	Crystal structure of mouse P-cadherin extracellular domains EC1-EC2 Descriptor: CALCIUM ION, COPPER (II) ION, Cadherin-3 Authors: Brasch, J, Shapiro, L. Deposit date: 2013-11-25 Release date: 2014-09-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014

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