8C5V
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7QJ9
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7QJ6
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1L5E
| The domain-swapped dimer of CV-N in solution | Descriptor: | Cyanovirin-N | Authors: | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | Deposit date: | 2002-03-06 | Release date: | 2002-06-05 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
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1DN9
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7YZY
| pMMO structure from native membranes by cryoET and STA | Descriptor: | Methane monooxygenase subunit C2, Particulate methane monooxygenase alpha subunit, Particulate methane monooxygenase beta subunit | Authors: | Zhu, Y, Ni, T, Zhang, P. | Deposit date: | 2022-02-21 | Release date: | 2022-08-10 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure and activity of particulate methane monooxygenase arrays in methanotrophs. Nat Commun, 13, 2022
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3LXR
| Shigella IpgB2 in complex with human RhoA and GDP (complex C) | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, IpgB2, SULFATE ION, ... | Authors: | Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. | Deposit date: | 2010-02-25 | Release date: | 2010-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
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3LWN
| Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex B) | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ... | Authors: | Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. | Deposit date: | 2010-02-24 | Release date: | 2010-03-31 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
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2LYH
| Structure of Faap24 residues 141-215 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wienk, H, Slootweg, J, Kaptein, R, Boelens, R, Folkers, G.E. | Deposit date: | 2012-09-18 | Release date: | 2013-05-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition. Nucleic Acids Res., 41, 2013
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7YUY
| Structure of a mutated membrane-bound glycosyltransferase | Descriptor: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J. | Deposit date: | 2022-08-18 | Release date: | 2023-03-29 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1. Nature, 616, 2023
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7ZAU
| Fascin-1 in complex with Nb 3E11 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ... | Authors: | Burgess, S.G, Bayliss, R. | Deposit date: | 2022-03-22 | Release date: | 2023-09-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation. Open Biology, 14, 2024
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2N1Q
| HIV-1 Core Packaging Signal | Descriptor: | RNA_(155-MER) | Authors: | Keane, S.C, Summers, M.F. | Deposit date: | 2015-04-15 | Release date: | 2015-05-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | RNA structure. Structure of the HIV-1 RNA packaging signal. Science, 348, 2015
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6ANU
| Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | Descriptor: | Actin, cytoplasmic 1, Spectrin beta chain, ... | Authors: | Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. | Deposit date: | 2017-08-14 | Release date: | 2017-11-22 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation. Nat Commun, 8, 2017
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309D
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3MOY
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8COG
| Human arginylated beta-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Pinto, C.S, Bakker, S.E, Suchenko, A, Hussain, H, Hatano, T, Sampath, K, Chinthalapudi, K, Mishima, M, Balasubramanian, M. | Deposit date: | 2023-02-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.499 Å) | Cite: | Structure and physiological investigation of human arginylated beta-actin To Be Published
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7ZTC
| Non-muscle F-actin decorated with non-muscle tropomyosin 1.6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 1.6, actin, ... | Authors: | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2022-05-09 | Release date: | 2023-01-11 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms. Cell Rep, 42, 2023
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7ZTD
| Non-muscle F-actin decorated with non-muscle tropomyosin 3.2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Non-muscle tropomyosin 3.2, actin, ... | Authors: | Selvaraj, M, Kokate, S, Kogan, K, Kotila, T, Kremneva, E, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2022-05-09 | Release date: | 2023-01-11 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms. Cell Rep, 42, 2023
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3OB4
| MBP-fusion protein of the major peanut allergen Ara h 2 | Descriptor: | CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ... | Authors: | Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C. | Deposit date: | 2010-08-06 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.706 Å) | Cite: | Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy, 66, 2011
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3MQM
| Crystal Structure of the Bromodomain of human ASH1L | Descriptor: | Probable histone-lysine N-methyltransferase ASH1L | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Felletar, I, Vollmar, M, Chaikuad, A, Krojer, T, Canning, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-28 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3NCC
| A human Prolactin receptor antagonist in complex with the mutant extracellular domain H188A of the human prolactin receptor | Descriptor: | CARBONATE ION, CHLORIDE ION, Prolactin, ... | Authors: | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | Deposit date: | 2010-06-04 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
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3NDN
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8DNH
| Cryo-EM structure of nonmuscle beta-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-11 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
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3MB3
| Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) | Descriptor: | 1-methylpyrrolidin-2-one, PH-interacting protein | Authors: | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-03-25 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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3MXF
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1 | Descriptor: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | Authors: | Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-07 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Selective inhibition of BET bromodomains. Nature, 468, 2010
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