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4RT3
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BU of 4rt3 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with (alpha, beta)-NH-(beta,gamma)-CH2-dTTP
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]amino}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2014-11-12
Release date:2015-07-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP.
Org.Lett., 17, 2015
4RT2
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BU of 4rt2 by Molmil
Ternary complex crystal structure of DNA polymerase Beta with (alpha,beta)-CH2-(beta,gamma)-NH-dTTP
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]methyl}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2014-11-12
Release date:2015-07-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP.
Org.Lett., 17, 2015
5ZUH
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BU of 5zuh by Molmil
Solution structure of RRM domain of La protein from Trypanosoma brucei
Descriptor: RNA binding protein La-like protein
Authors:Shan, F.Z.
Deposit date:2018-05-07
Release date:2019-05-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A telomerase subunit homolog La protein from Trypanosoma brucei plays an essential role in ribosomal biogenesis.
Febs J., 286, 2019
4I1T
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BU of 4i1t by Molmil
Crystal structure of the cap-snatching endonuclease from Pichinde virus
Descriptor: RNA-directed RNA polymerase L
Authors:Bussetta, C, Choi, K.H.
Deposit date:2012-11-21
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the cap-snatching endonuclease from Pichinde virus, a new world arenavirus
To be Published
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-06
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-07
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
7PRE
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BU of 7pre by Molmil
Solution structure of the NRDI domain of Nab3
Descriptor: HLJ1_G0022400.mRNA.1.CDS.1
Authors:Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M.
Deposit date:2021-09-21
Release date:2022-01-12
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural basis of Nrd1-Nab3 heterodimerization.
Life Sci Alliance, 5, 2022
3PMN
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BU of 3pmn by Molmil
ternary crystal structure of polymerase lambda variant with a GT mispair at the primer terminus with Mn2+ in the active site
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, 5'-D(*CP*AP*GP*TP*AP*G)-3', 5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3', ...
Authors:Bebenek, K, Pedersen, L.C, Kunkel, T.A.
Deposit date:2010-11-17
Release date:2011-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Replication infidelity via a mismatch with Watson-Crick geometry.
Proc.Natl.Acad.Sci.USA, 108, 2011
7Z27
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BU of 7z27 by Molmil
Crystal structure of the SPOC domain of human RBM15
Descriptor: RNA-binding protein 15
Authors:Grishkovskaya, I, Appel, L.M, Djinovic-Carugo, K, Slade, D.
Deposit date:2022-02-25
Release date:2022-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators.
Nat Commun, 14, 2023
5SUQ
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BU of 5suq by Molmil
Crystal structure of the THO-Sub2 complex
Descriptor: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ...
Authors:Ren, Y, Blobel, G.
Deposit date:2016-08-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (6 Å)
Cite:Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Elife, 6, 2017
5URN
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BU of 5urn by Molmil
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the transactivation domain 1 of p65
Descriptor: RNA polymerase II transcription factor B subunit 1, Transcription factor p65
Authors:Lecoq, L, Omichinski, J.G, Raiola, L, Cyr, N, Chabot, P, Arseneault, G, Legault, P.
Deposit date:2017-02-11
Release date:2017-03-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-kappa B and transcription regulatory factors.
Nucleic Acids Res., 45, 2017
1OU5
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BU of 1ou5 by Molmil
Crystal structure of human CCA-adding enzyme
Descriptor: tRNA CCA-adding enzyme
Authors:Augustin, M.A, Reichert, A.S, Betat, H, Huber, R, Moerl, M, Steegborn, C.
Deposit date:2003-03-24
Release date:2003-05-06
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of the Human CCA-adding Enzyme: Insights into Template-independent Polymerization
J.Mol.Biol., 328, 2003
5EMX
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BU of 5emx by Molmil
Crystal structure of the S. cerevisiae Rtf1 histone modification domain mutant R124A R126A R128A
Descriptor: RNA polymerase-associated protein RTF1
Authors:Wier, A.D, Heroux, A, VanDemark, A.P.
Deposit date:2015-11-06
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Mol.Cell, 64, 2016
3FKE
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BU of 3fke by Molmil
Structure of the Ebola VP35 Interferon Inhibitory Domain
Descriptor: Polymerase cofactor VP35
Authors:Amarasinghe, G.K, Leung, D.W, Ginder, N.D, Honzatko, R.B, Nix, J, Basler, C.F, Fulton, D.B.
Deposit date:2008-12-16
Release date:2009-01-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the Ebola VP35 interferon inhibitory domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
7Y5M
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BU of 7y5m by Molmil
The OTU domain of Tacheng Tick Virus 1
Descriptor: RNA-directed RNA polymerase
Authors:Li, Z, Wang, W.J, Xiao, Y.S, Sun, L.T.
Deposit date:2022-06-17
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The OTU domain of Tacheng Tick Virus 1
To Be Published
7YZV
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BU of 7yzv by Molmil
Ryegrass mottle virus serine protease domain S159A mutant
Descriptor: RNA-directed RNA polymerase
Authors:Kalnins, G.
Deposit date:2022-02-21
Release date:2022-03-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:VPg Impact on Ryegrass Mottle Virus Serine-like 3C Protease Proteolysis and Structure.
Int J Mol Sci, 24, 2023
3DGP
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BU of 3dgp by Molmil
Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
Descriptor: RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5
Authors:Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A.
Deposit date:2008-06-14
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
3DOM
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BU of 3dom by Molmil
Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
Descriptor: RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5
Authors:Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A.
Deposit date:2008-07-04
Release date:2008-08-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
4OWR
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BU of 4owr by Molmil
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair Rae1-Nup98
Descriptor: Matrix protein, Nuclear pore complex protein Nup98-Nup96, mRNA export factor
Authors:Ren, Y, Quan, B, Seo, H.S, Blobel, G.
Deposit date:2014-02-03
Release date:2014-06-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 Nup98).
Proc.Natl.Acad.Sci.USA, 111, 2014
2B7E
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BU of 2b7e by Molmil
First FF domain of Prp40 Yeast Protein
Descriptor: Pre-mRNA processing protein PRP40
Authors:Gasch, A, Wiesner, S, Martin-Malpartida, P, Ramirez-Espain, X, Ruiz, L, Macias, M.J.
Deposit date:2005-10-04
Release date:2005-11-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of Prp40 FF1 domain and its interaction with the crn-TPR1 motif of Clf1 gives a new insight into the binding mode of FF domains.
J.Biol.Chem., 281, 2006
4TQS
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BU of 4tqs by Molmil
Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dCTP
Descriptor: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ...
Authors:Zhao, L.
Deposit date:2014-06-11
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
4TQR
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BU of 4tqr by Molmil
Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dTTP
Descriptor: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ...
Authors:Zhao, L.
Deposit date:2014-06-11
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54, 2015
4KHQ
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BU of 4khq by Molmil
Ternary complex of RB69 mutant L415F wit DUMPNPP
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Clausen, A.R, Pedersen, L.C.
Deposit date:2013-05-01
Release date:2013-10-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:Structure-function analysis of ribonucleotide bypass by B family DNA replicases.
Proc.Natl.Acad.Sci.USA, 110, 2013
6BEM
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BU of 6bem by Molmil
Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-O-[(R)-{[(R)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxycytidine, CHLORIDE ION, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2017-10-25
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018

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