7CH7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ch7 by Molmil](/molmil-images/mine/7ch7) | Cryo-EM structure of E.coli MlaFEB | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, Phospholipid ABC transporter ATP-binding protein MlaF | Authors: | Zhou, C, Shi, H, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
|
|
7CHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cha by Molmil](/molmil-images/mine/7cha) | Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
|
|
7O80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o80 by Molmil](/molmil-images/mine/7o80) | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | Deposit date: | 2021-04-14 | Release date: | 2021-06-02 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7MPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mpe by Molmil](/molmil-images/mine/7mpe) | |
6ZE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ze1 by Molmil](/molmil-images/mine/6ze1) | human NBD1 of CFTR in complex with nanobody G11a | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | Authors: | Garcia-Pino, A, Govaerts, C, Scholl, D, Sigoillot, M. | Deposit date: | 2020-06-15 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | A topological switch in CFTR modulates channel activity and sensitivity to unfolding. Nat.Chem.Biol., 17, 2021
|
|
7E7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7q by Molmil](/molmil-images/mine/7e7q) | Cryo-EM structure of human ABCA4 in ATP-bound state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Xie, T, Zhang, Z.K, Gong, X. | Deposit date: | 2021-02-26 | Release date: | 2021-06-30 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of substrate recognition and translocation by human ABCA4. Nat Commun, 12, 2021
|
|
7E7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7i by Molmil](/molmil-images/mine/7e7i) | Cryo-EM structure of human ABCA4 in the apo state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | Authors: | Xie, T, Zhang, Z.K, Gong, X. | Deposit date: | 2021-02-26 | Release date: | 2021-06-30 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of substrate recognition and translocation by human ABCA4. Nat Commun, 12, 2021
|
|
7E7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7o by Molmil](/molmil-images/mine/7e7o) | Cryo-EM structure of human ABCA4 in NRPE-bound state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | Authors: | Xie, T, Zhang, Z.K, Gong, X. | Deposit date: | 2021-02-26 | Release date: | 2021-06-30 | Last modified: | 2021-07-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of substrate recognition and translocation by human ABCA4. Nat Commun, 12, 2021
|
|
7OJH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ojh by Molmil](/molmil-images/mine/7ojh) | ABCG2 topotecan turnover-1 state | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | Deposit date: | 2021-05-15 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
|
|
7OJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oj8 by Molmil](/molmil-images/mine/7oj8) | ABCG2 E1S turnover-2 state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ... | Authors: | Ni, D, Yu, Q, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | Deposit date: | 2021-05-14 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
|
|
7OJI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oji by Molmil](/molmil-images/mine/7oji) | ABCG2 topotecan turnover-2 state | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... | Authors: | Yu, Q, Ni, D, Kowal, J, Manolaridis, I, Jackson, S.M, Stahlberg, H, Locher, K.P. | Deposit date: | 2021-05-16 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism. Nat Commun, 12, 2021
|
|
7CH6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ch6 by Molmil](/molmil-images/mine/7ch6) | Cryo-EM structure of E.coli MlaFEB with AMPPNP | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-08-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
|
|
7MDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mdy by Molmil](/molmil-images/mine/7mdy) | LolCDE nucleotide-bound | Descriptor: | ADP ORTHOVANADATE, Lipo-releasing system transmembrane protein lolC, Lipoprotein transporter subunit LolE, ... | Authors: | Sharma, S, Liao, M. | Deposit date: | 2021-04-06 | Release date: | 2021-08-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins Nat Commun, 12, 2021
|
|
7MDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mdx by Molmil](/molmil-images/mine/7mdx) | LolCDE nucleotide-free | Descriptor: | (2R)-2-(tridecanoyloxy)propyl hexadecanoate, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, ... | Authors: | Sharma, S, Liao, M. | Deposit date: | 2021-04-06 | Release date: | 2021-08-11 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins Nat Commun, 12, 2021
|
|
7NNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nnu by Molmil](/molmil-images/mine/7nnu) | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs | Descriptor: | Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2021-02-25 | Release date: | 2021-08-18 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nnt by Molmil](/molmil-images/mine/7nnt) | Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | Deposit date: | 2021-02-25 | Release date: | 2021-08-18 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niu by Molmil](/molmil-images/mine/7niu) | |
7NIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niv by Molmil](/molmil-images/mine/7niv) | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | Descriptor: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ... | Authors: | Nosol, K, Locher, K.P. | Deposit date: | 2021-02-14 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7NIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7niw by Molmil](/molmil-images/mine/7niw) | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation) | Descriptor: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ... | Authors: | Nosol, K, Locher, K.P. | Deposit date: | 2021-02-14 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7EKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ekm by Molmil](/molmil-images/mine/7ekm) | Mitochondrial outer membrane protein | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial | Authors: | Zhang, S.S. | Deposit date: | 2021-04-05 | Release date: | 2021-08-25 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular insights into the human ABCB6 transporter. Cell Discov, 7, 2021
|
|
7EKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ekl by Molmil](/molmil-images/mine/7ekl) | Mitochondrial outer membrane protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION | Authors: | Zhang, S.S. | Deposit date: | 2021-04-05 | Release date: | 2021-08-25 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular insights into the human ABCB6 transporter. Cell Discov, 7, 2021
|
|
7KYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kyp by Molmil](/molmil-images/mine/7kyp) | |
7KYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kyo by Molmil](/molmil-images/mine/7kyo) | |
7MBZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mbz by Molmil](/molmil-images/mine/7mbz) | |
7MC0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mc0 by Molmil](/molmil-images/mine/7mc0) | |