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2QM9
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Troglitazone Bound to Fatty Acid Binding Protein 4
Descriptor: (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, Fatty acid-binding protein, adipocyte, ...
Authors:Gillilan, R.E, Ayers, S.D, Noy, N.
Deposit date:2007-07-14
Release date:2007-10-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Basis for Activation of Fatty Acid-binding Protein 4
J.Mol.Biol., 372, 2007
2QQ5
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Crystal structure of human SDR family member 1
Descriptor: Dehydrogenase/reductase SDR family member 1
Authors:Pilka, E.S, Hozjan, V, Ugochukwu, E, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-07-26
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human SDR family member 1.
TO BE PUBLISHED
2QCQ
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Crystal structure of Bone Morphogenetic Protein-3 (BMP-3)
Descriptor: Bone morphogenetic protein 3
Authors:Allendorph, G.P.
Deposit date:2007-06-19
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors.
Biochemistry, 46, 2007
2QG8
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Plasmodium yoelii acyl carrier protein synthase PY06285 with ADP bound
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Acyl Carrier Protein Synthase PY06285, MAGNESIUM ION
Authors:Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Brokx, S, Altamentova, S, Structural Genomics Consortium (SGC)
Deposit date:2007-06-28
Release date:2007-07-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Plasmodium yoelii acyl carrier protein synthase PY06285 with ADP bound
TO BE PUBLISHED
2QIA
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Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine Acyltransferase
Descriptor: UDP-N-acetylglucosamine acyltransferase, uridine-5'-diphosphate-3-O-(R-3-hydroxymyristoyl)-N-acetyl-D-glucosamine
Authors:Williams, A.H, Raetz, C.R.H.
Deposit date:2007-07-03
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R3P
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Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Descriptor: 5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2
Authors:Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S.
Deposit date:2007-08-29
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure-guided discovery of cyclin-dependent kinase inhibitors.
Biopolymers, 89, 2008
2QFT
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E.coli EPSP synthase Pro101Ser liganded with S3P and glyphosate
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, GLYPHOSATE, ...
Authors:Schonbrunn, E, Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QG7
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Plasmodium vivax ethanolamine kinase Pv091845
Descriptor: SULFATE ION, ethanolamine kinase Pv091845
Authors:Lunin, V.V, Wernimont, A.K, Mulichak, A, Lew, J, Wasney, G, Senisterra, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Hills, T, Artz, J, Xiao, T, Structural Genomics Consortium (SGC)
Deposit date:2007-06-28
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.407 Å)
Cite:Plasmodium vivax ethanolamine kinase Pv091845
TO BE PUBLISHED
2R3K
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Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor
Descriptor: 3-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine, Cell division protein kinase 2
Authors:Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S.
Deposit date:2007-08-29
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-guided discovery of cyclin-dependent kinase inhibitors.
Biopolymers, 89, 2008
2QT4
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Atomic-resolution crystal structure of the natural form of Scytovirin
Descriptor: scytovirin
Authors:Moulaei, T, Botos, I, Ziolkowska, N.E, Dauter, Z, Wlodawer, A.
Deposit date:2007-08-01
Release date:2007-11-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Atomic-resolution crystal structure of the antiviral lectin scytovirin.
Protein Sci., 16, 2007
2QUD
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PP7 Coat Protein Dimer
Descriptor: Coat protein, GLYCEROL
Authors:Chao, J.A.
Deposit date:2007-08-04
Release date:2007-12-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for the coevolution of a viral RNA-protein complex.
Nat.Struct.Mol.Biol., 15, 2008
2QUA
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Crystal structure of LipA from Serratia marcescens
Descriptor: CALCIUM ION, Extracellular lipase
Authors:Meier, R, Baumann, U.
Deposit date:2007-08-04
Release date:2007-08-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A calcium-gated lid and a large beta-roll sandwich are revealed by the crystal structure of extracellular lipase from Serratia marcescens.
J.Biol.Chem., 282, 2007
2QIQ
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Structure-based Design and Synthesis and Biological Evaluation of Peptidomimetic SARS-3CLpro Inhibitors
Descriptor: ETHYL (4R)-4-{[(2R,5S)-5-{[N-(TERT-BUTOXYCARBONYL)-L-SERYL]AMINO}-6-METHYL-2-(3-METHYLBUT-2-EN-1-YL)-4-OXOHEPTANOYL]AMINO}-5-[(3R)-2-OXOPYRROLIDIN-3-YL]PENTANOATE, Replicase polyprotein 1ab
Authors:Grum-Tokars, V.
Deposit date:2007-07-05
Release date:2008-02-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2QJ9
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Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QFS
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BU of 2qfs by Molmil
E.coli EPSP synthase Pro101Ser liganded with S3P
Descriptor: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE
Authors:Schonbrunn, E, Healy-Fried, M.L.
Deposit date:2007-06-28
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
J.Biol.Chem., 282, 2007
2QTJ
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BU of 2qtj by Molmil
Solution structure of human dimeric immunoglobulin A
Descriptor: Ig alpha-1 chain C region, Kappa light chain IgA1
Authors:Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J.
Deposit date:2007-08-02
Release date:2008-01-22
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy
J.Immunol., 180, 2008
2QJA
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BU of 2qja by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QK7
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A covalent S-F heterodimer of staphylococcal gamma-hemolysin
Descriptor: Gamma-hemolysin component A, Gamma-hemolysin component B
Authors:Roblin, P, Guillet, V, Maveyraud, L, Mourey, L.
Deposit date:2007-07-10
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins.
Proteins, 71, 2008
2QDJ
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BU of 2qdj by Molmil
Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
Descriptor: Retinoblastoma-associated protein
Authors:Hassler, M, Mittnacht, S, Pearl, L.H.
Deposit date:2007-06-21
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
2QEP
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BU of 2qep by Molmil
Crystal structure of the D1 domain of PTPRN2 (IA2beta)
Descriptor: CHLORIDE ION, Receptor-type tyrosine-protein phosphatase N2
Authors:Ugochukwu, E, Barr, A, Alfano, I, Berridge, G, Burgess-Brown, N, Das, S, Fedorov, O, King, O, Niesen, F, Watt, S, Savitsky, P, Salah, E, Pike, A.C.W, Bunkoczi, G, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C.H, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-06-26
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2QSS
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BU of 2qss by Molmil
Bovine hemoglobin at pH 6.3
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QJB
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Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
Descriptor: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
Authors:Kotzsch, A, Mueller, T.D.
Deposit date:2007-07-06
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QNI
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Crystal structure of uncharacterized protein Atu0299
Descriptor: Uncharacterized protein Atu0299
Authors:Dong, A, Xu, X, Gu, J, Zheng, H, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-07-18
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of uncharacterized protein Atu0299.
To be Published
2QLE
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GFP/S205V mutant
Descriptor: Green fluorescent protein, IMIDAZOLE
Authors:Shu, X, Remington, S.J.
Deposit date:2007-07-12
Release date:2008-02-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:An alternative excited-state proton transfer pathway in green fluorescent protein variant S205V.
Protein Sci., 16, 2007
2QUI
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BU of 2qui by Molmil
Crystal structures of human tryptophanyl-tRNA synthetase in complex with Tryptophanamide and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, L-TRYPTOPHANAMIDE, MAGNESIUM ION, ...
Authors:Shen, N, Ding, J.P.
Deposit date:2007-08-05
Release date:2008-04-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Nucleic Acids Res., 36, 2008

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