1SOJ
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![BU of 1soj by Molmil](/molmil-images/mine/1soj) | CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B IN COMPLEX WITH IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Authors: | Scapin, G, Patel, S.B, Chung, C, Varnerin, J.P, Edmondson, S.D, Mastracchio, A, Parmee, E.R, Becker, J.W, Singh, S.B, Van Der Ploeg, L.H, Tota, M.R. | Deposit date: | 2004-03-15 | Release date: | 2004-05-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity Biochemistry, 43, 2004
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6KUR
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![BU of 6kur by Molmil](/molmil-images/mine/6kur) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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3MUJ
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![BU of 3muj by Molmil](/molmil-images/mine/3muj) | Early B-cell factor 3 (EBF3) IPT/TIG and dimerization helices | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Transcription factor COE3 | Authors: | Siponen, M.I, Lehtio, L, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schueler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-05-03 | Release date: | 2010-06-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
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1SHX
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![BU of 1shx by Molmil](/molmil-images/mine/1shx) | Ephrin A5 ligand structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin-A5 | Authors: | Himanen, J.P, Barton, W.A, Nikolov, D.B, Jeffrey, P.D. | Deposit date: | 2004-02-26 | Release date: | 2005-04-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. J.Biol.Chem., 280, 2005
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2Z66
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![BU of 2z66 by Molmil](/molmil-images/mine/2z66) | Crystal structure of the VT3 hybrid of human TLR4 and hagfish VLRB.61 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ... | Authors: | Lee, J.-O, Kim, H.M, Park, B.S. | Deposit date: | 2007-07-22 | Release date: | 2007-09-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130, 2007
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4KU8
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![BU of 4ku8 by Molmil](/molmil-images/mine/4ku8) | Structures of PKGI Reveal a cGMP-Selective Activation Mechanism | Descriptor: | GLYCINE, cGMP-dependent Protein Kinase 1 | Authors: | Huang, G.Y, Kim, J.J, Reger, A.S, Lorenz, R, Moon, E.W, Casteel, D.E, Sankaran, B, Herberg, F.W, Kim, C. | Deposit date: | 2013-05-21 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.994 Å) | Cite: | Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I. Structure, 22, 2014
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1F0W
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![BU of 1f0w by Molmil](/molmil-images/mine/1f0w) | CRYSTAL STRUCTURE OF ORTHORHOMBIC LYSOZYME GROWN AT PH 6.5 | Descriptor: | LYSOZYME | Authors: | Biswal, B.K, Sukumar, N, Vijayan, M. | Deposit date: | 2000-05-17 | Release date: | 2000-06-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Hydration, mobility and accessibility of lysozyme: structures of a pH 6.5 orthorhombic form and its low-humidity variant and a comparative study involving 20 crystallographically independent molecules. Acta Crystallogr.,Sect.D, 56, 2000
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8C0O
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![BU of 8c0o by Molmil](/molmil-images/mine/8c0o) | |
8HRX
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![BU of 8hrx by Molmil](/molmil-images/mine/8hrx) | Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex | Descriptor: | Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ... | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2022-12-16 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31, 2024
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1F10
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![BU of 1f10 by Molmil](/molmil-images/mine/1f10) | |
5BTG
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![BU of 5btg by Molmil](/molmil-images/mine/5btg) | Crystal structure of a topoisomerase II complex | Descriptor: | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA gyrase subunit A, DNA gyrase subunit B, ... | Authors: | Blower, T.R, Williamson, B.H, Kerns, R.J, Berger, J.M. | Deposit date: | 2015-06-03 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 113, 2016
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6I96
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![BU of 6i96 by Molmil](/molmil-images/mine/6i96) | |
7KDP
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![BU of 7kdp by Molmil](/molmil-images/mine/7kdp) | HCMV prefusion gB in complex with fusion inhibitor WAY-174865 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | Authors: | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | Deposit date: | 2020-10-09 | Release date: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion. Sci Adv, 7, 2021
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7K7G
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![BU of 7k7g by Molmil](/molmil-images/mine/7k7g) | nucleosome and Gal4 complex | Descriptor: | Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ... | Authors: | Ruifang, G, Yawen, B. | Deposit date: | 2020-09-22 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation. Nat Commun, 12, 2021
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1FGA
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![BU of 1fga by Molmil](/molmil-images/mine/1fga) | |
4M3L
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![BU of 4m3l by Molmil](/molmil-images/mine/4m3l) | Crystal Structure of the coiled coil domain of MuRF1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, E3 ubiquitin-protein ligase TRIM63, ... | Authors: | Mayans, O, Franke, B. | Deposit date: | 2013-08-06 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1. Open Biol, 4, 2014
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5IPI
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![BU of 5ipi by Molmil](/molmil-images/mine/5ipi) | Structure of Adeno-associated virus type 2 VLP | Descriptor: | Capsid protein VP1 | Authors: | Drouin, L.M, Lins, B, Janssen, M.E, Bennet, A, Chipman, P, McKenna, R, Chen, W, Muzyczka, N, Cardone, G, Baker, T.S, Agbandje-McKenna, M. | Deposit date: | 2016-03-09 | Release date: | 2016-07-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging. J.Virol., 90, 2016
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6KUT
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![BU of 6kut by Molmil](/molmil-images/mine/6kut) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2) | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | Deposit date: | 2019-09-02 | Release date: | 2019-10-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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330D
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![BU of 330d by Molmil](/molmil-images/mine/330d) | |
7YWZ
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![BU of 7ywz by Molmil](/molmil-images/mine/7ywz) | Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 4 spermine molecules at 1.75 A resolution | Descriptor: | GLYCEROL, Oligopeptidase B, SPERMINE | Authors: | Petrenko, D.E, Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Mikhailova, A.G, Timofeev, V.I, Rakitina, T.V. | Deposit date: | 2022-02-15 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 4 spermine molecules at 1.75 A resolution To Be Published
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5TQX
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![BU of 5tqx by Molmil](/molmil-images/mine/5tqx) | CryoEM reconstruction of human IKK1, intermediate conformation 2 | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit alpha | Authors: | Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O. | Deposit date: | 2016-10-24 | Release date: | 2016-11-09 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structural Basis for the Activation of IKK1/ alpha. Cell Rep, 17, 2016
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4D71
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![BU of 4d71 by Molmil](/molmil-images/mine/4d71) | Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 2 blood group A-tetrasaccharide (E558A X02 mutant) | Descriptor: | 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, SULFATE ION, ... | Authors: | Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. | Deposit date: | 2014-11-19 | Release date: | 2015-01-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
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6A6H
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![BU of 6a6h by Molmil](/molmil-images/mine/6a6h) | |
7KE0
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![BU of 7ke0 by Molmil](/molmil-images/mine/7ke0) | |
5IS5
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![BU of 5is5 by Molmil](/molmil-images/mine/5is5) | |