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6ZXC
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BU of 6zxc by Molmil
Diguanylate cyclase DgcR (I-site mutant) in activated state
Descriptor: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
6ZXB
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BU of 6zxb by Molmil
Diguanylate cyclase DgcR (I-site mutant) in native state
Descriptor: 1,2-ETHANEDIOL, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
6EO3
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BU of 6eo3 by Molmil
Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. S207C P212121
Descriptor: SULFATE ION, Transcriptional regulatory protein RcsB
Authors:Casino, P, Marina, A.
Deposit date:2017-10-08
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
2AYX
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BU of 2ayx by Molmil
Solution structure of the E.coli RcsC C-terminus (residues 700-949) containing linker region and phosphoreceiver domain
Descriptor: Sensor kinase protein rcsC
Authors:Rogov, V.V, Rogova, N.Y, Bernhard, F, Koglin, A, Lohr, F, Dotsch, V.
Deposit date:2005-09-09
Release date:2006-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A New Structural Domain in the Escherichia coli RcsC Hybrid Sensor Kinase Connects Histidine Kinase and Phosphoreceiver Domains
J.Mol.Biol., 364, 2006
5F64
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BU of 5f64 by Molmil
Putative positive transcription regulator (sensor EvgS) from Shigella flexneri
Descriptor: Positive transcription regulator EvgA
Authors:Nocek, B, Osipiuk, J, Mulligan, R, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-12-05
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Putative positive transcription regulator (sensor EvgS) from Shigella flexneri.
to be published
6EO2
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BU of 6eo2 by Molmil
Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. S207C crossed
Descriptor: Transcriptional regulatory protein RcsB
Authors:Casino, P, Marina, A.
Deposit date:2017-10-08
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
8TFF
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BU of 8tff by Molmil
PorX with BeF3 phosphate analog
Descriptor: ACETATE ION, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ...
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-11
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:PorX with BeF3 phosphate analog
To Be Published
8TEF
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BU of 8tef by Molmil
PorX primitive monoclinic crystal form
Descriptor: MAGNESIUM ION, Response regulator receiver protein, SULFATE ION
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-06
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:PorX primitive monoclinic crystal form
To Be Published
8THP
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BU of 8thp by Molmil
PorX phosphatase null mutant (T271V)
Descriptor: CALCIUM ION, GLYCEROL, Response regulator receiver protein
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-17
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:PorX phosphatase null mutant (T271V)
To Be Published
8TED
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BU of 8ted by Molmil
PorX primitive orthorhombic crystal form
Descriptor: ACETATE ION, BROMIDE ION, CALCIUM ION, ...
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-06
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:PorX primitive orthorhombic crystal form
To Be Published
8TFM
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BU of 8tfm by Molmil
PorX with Zn (primitive orthorhombic crystal form)
Descriptor: GLYCEROL, Response regulator receiver protein, ZINC ION
Authors:Saran, A, Zeytuni, N.
Deposit date:2023-07-11
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:PorX with Zn (primitive orthorhombic crystal form)
To Be Published
8UVK
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BU of 8uvk by Molmil
CosR DNA bound form II
Descriptor: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*T)-3'), ...
Authors:Zhang, Z.
Deposit date:2023-11-03
Release date:2024-01-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator.
Mbio, 15, 2024
8UUZ
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BU of 8uuz by Molmil
Campylobacter jejuni CosR apo form
Descriptor: DNA-binding response regulator
Authors:Zhang, Z.
Deposit date:2023-11-02
Release date:2024-01-31
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator.
Mbio, 15, 2024
8UVX
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BU of 8uvx by Molmil
CosR DNA bound form I
Descriptor: DNA (5'-D(*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*TP*TP*TP*GP*GP*TP*TP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*T)-3'), DNA-binding response regulator
Authors:Zhang, Z.
Deposit date:2023-11-05
Release date:2024-01-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator.
Mbio, 15, 2024
5U8K
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BU of 5u8k by Molmil
RitR mutant - C128S
Descriptor: Response regulator
Authors:Silvaggi, N.R, Han, L.
Deposit date:2016-12-14
Release date:2017-12-20
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
5U8M
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BU of 5u8m by Molmil
A novel family of redox sensors in the streptococci evolved from two-component response regulators
Descriptor: Response regulator
Authors:Han, L, Silvaggi, N.R.
Deposit date:2016-12-14
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
5UHT
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BU of 5uht by Molmil
Structure of the Thermotoga maritima HK853-BeF3-RR468 complex at pH 5.0
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Liu, Y, Rose, J, Jiang, L, Zhou, P.
Deposit date:2017-01-12
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
Nat Commun, 8, 2017
5UXW
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BU of 5uxw by Molmil
Crystal Structure of Anti-anti-sigma factor PhyR from Bartonella quintana
Descriptor: 1,2-ETHANEDIOL, Sensory transduction regulatory protein
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-02-23
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Anti-anti-sigma factor PhyR from Bartonella quintana
to be published
5UXV
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BU of 5uxv by Molmil
Crystal Structure of Anti-anti-sigma factor PhyR I40V/S51C mutant from Bartonella quintana
Descriptor: 1,2-ETHANEDIOL, Sensory transduction regulatory protein
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-02-23
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Anti-anti-sigma factor PhyR I40V/S51C mutant from Bartonella quintana
to be published
1KMI
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BU of 1kmi by Molmil
CRYSTAL STRUCTURE OF AN E.COLI CHEMOTAXIS PROTEIN, CHEZ
Descriptor: BERYLLIUM TRIFLUORIDE ION, BICINE, Chemotaxis protein cheY, ...
Authors:Zhao, R, Collins, E.J, Bourret, R.B, Silversmith, R.E.
Deposit date:2001-12-16
Release date:2002-07-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and catalytic mechanism of the E. coli chemotaxis phosphatase CheZ.
Nat.Struct.Biol., 9, 2002
5W43
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BU of 5w43 by Molmil
Structure of the two-component response regulator RcsB-DNA complex
Descriptor: DNA (5'-D(*GP*AP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*TP*AP*AP*GP*AP*TP*TP*TP*TP*TP*CP*CP*TP*AP*AP*AP*TP*C)-3'), Transcriptional regulatory protein RcsB
Authors:Filippova, E.V, Warwzak, Z, Pshenychnyi, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-06-09
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
MBio, 9, 2018
5VXN
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BU of 5vxn by Molmil
Structure of two RcsB dimers bound to two parallel DNAs.
Descriptor: DNA (5'-D(*GP*AP*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*AP*AP*AP*AP*AP*TP*CP*TP*TP*AP*GP*A)-3'), Transcriptional regulatory protein RcsB
Authors:Filippova, E.V, Minasov, G, Pshenychnyi, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-05-23
Release date:2018-03-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.375 Å)
Cite:Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
MBio, 9, 2018
5VFA
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BU of 5vfa by Molmil
RitR Mutant - C128D
Descriptor: Response regulator
Authors:Han, L, Silvaggi, N.R.
Deposit date:2017-04-07
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
1KGS
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BU of 1kgs by Molmil
Crystal Structure at 1.50 A of an OmpR/PhoB Homolog from Thermotoga maritima
Descriptor: DNA BINDING RESPONSE REGULATOR D, THIOCYANATE ION
Authors:Buckler, D.R, Zhou, Y, Stock, A.M.
Deposit date:2001-11-28
Release date:2001-12-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Evidence of intradomain and interdomain flexibility in an OmpR/PhoB homolog from Thermotoga maritima.
Structure, 10, 2002
2R25
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BU of 2r25 by Molmil
Complex of YPD1 and SLN1-R1 with bound Mg2+ and BeF3-
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Osmosensing histidine protein kinase SLN1, ...
Authors:Copeland, D.M, Zhao, X, Soares, A.S, West, A.H.
Deposit date:2007-08-24
Release date:2008-01-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a complex between the phosphorelay protein YPD1 and the response regulator domain of SLN1 bound to a phosphoryl analog
J.Mol.Biol., 375, 2008

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