9FK3
 
 | | The structure of glycosynthase XT6 (E265G mutant), the extracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylotetraose-F molecules | | Descriptor: | CHLORIDE ION, Endo-1,4-beta-xylanase, ZINC ION, ... | | Authors: | Hadad, N, Chmelnik, O, Dessau, M, Shoham, Y, Shoham, G. | | Deposit date: | 2024-06-01 | | Release date: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structure of glycosynthase XT6 (E265G mutant), the extracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylotetraose-F molecules
To Be Published
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4CQA
 | | Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with IDI-6273 | | Descriptor: | 2-(4-chlorobenzyl)-8-ethoxy-1,3-dimethylcyclohepta[c]pyrrol-4(2H)-one, DIHYDROOROTATE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Rowland, P. | | Deposit date: | 2014-02-12 | | Release date: | 2014-04-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | In Vitro Resistance Selections for Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-Binding Site and Altered Growth.
J.Biol.Chem., 289, 2014
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3N6L
 | | The crystal structure of RNA-dependent RNA polymerase of EV71 virus | | Descriptor: | NICKEL (II) ION, RNA-dependent RNA polymerase | | Authors: | Wu, Y, Rao, Z.H. | | Deposit date: | 2010-05-26 | | Release date: | 2011-06-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
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3I04
 | | Cyanide-bound structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase from Moorella thermoacetica, cyanide-bound C-cluster | | Descriptor: | ACETATE ION, COPPER (I) ION, CYANIDE ION, ... | | Authors: | Kung, Y, Doukov, T.I, Drennan, C.L. | | Deposit date: | 2009-06-24 | | Release date: | 2009-09-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase.
Biochemistry, 48, 2009
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9FK4
 | | The structure of glycosynthase XT6 (E265G mutant), the extracellular xylanase of G.proteiniphilus T-6 in complex with xylohexaose-F molecule | | Descriptor: | CHLORIDE ION, Endo-1,4-beta-xylanase, ZINC ION, ... | | Authors: | Hadad, N, Chmelnik, O, Dessau, M, Shoham, Y, Shoham, G. | | Deposit date: | 2024-06-01 | | Release date: | 2025-06-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structure of glycosynthase XT6 (E265G mutant), the extracellular xylanase of G.proteiniphilus T-6 in complex with xylohexaose-F molecule
To Be Published
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3F43
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9FKL
 | | The structure of glycosynthase IXT6 (E241G mutant), the intracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylohexaose-F molecules | | Descriptor: | Beta-xylanase, beta-D-xylopyranose-(1-4)-1-fluoro-D-xylopyranose, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-1-fluoro-D-xylopyranose | | Authors: | Hadad, N, Chmelnik, O, Dessau, M, Shoham, Y, Shoham, G. | | Deposit date: | 2024-06-03 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structure of glycosynthase IXT6 (E241G mutant), the intracellular xylanase of G.proteiniphilus T-6 in complex with xylobiose-F and xylohexaose-F molecules
To Be Published
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5AG0
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5V1X
 | | Carbon Sulfoxide lyase, Egt2 Y134F in complex with its substrate | | Descriptor: | (1S)-2-{2-[(R)-(2R)-2-amino-2-carboxyethanesulfinyl]-1H-imidazol-4-yl}-1-carboxy-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase | | Authors: | Irani, S, Zhang, Y. | | Deposit date: | 2017-03-02 | | Release date: | 2018-03-07 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.558 Å) | | Cite: | Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
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5A05
 | | Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with maltotriose | | Descriptor: | ALDOSE-ALDOSE OXIDOREDUCTASE, MALONATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Taberman, H, Rouvinen, J, Parkkinen, T. | | Deposit date: | 2015-04-17 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.897 Å) | | Cite: | Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
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5XUS
 | | Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TTTA PAM) | | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*A)-3'), ... | | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | | Deposit date: | 2017-06-26 | | Release date: | 2017-08-09 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
Mol. Cell, 67, 2017
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7ZP7
 | | Crystal structure of evolved photoenzyme EnT1.3 (truncated) with bound product | | Descriptor: | (1~{R},10~{R},12~{S})-15-oxa-8-azatetracyclo[8.5.0.0^{1,12}.0^{2,7}]pentadeca-2(7),3,5-trien-9-one, 1,2-ETHANEDIOL, EnT1.3 C | | Authors: | Hardy, F.J, Levy, C. | | Deposit date: | 2022-04-26 | | Release date: | 2022-09-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A designed photoenzyme for enantioselective [2+2] cycloadditions.
Nature, 611, 2022
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3HAZ
 | | Crystal structure of bifunctional proline utilization A (PutA) protein | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Tanner, J.J. | | Deposit date: | 2009-05-03 | | Release date: | 2010-02-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
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6ARY
 | | Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor | | Descriptor: | (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | | Authors: | Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. | | Deposit date: | 2017-08-23 | | Release date: | 2018-01-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.257 Å) | | Cite: | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance.
Structure, 26, 2018
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7ZKJ
 | | CODH/ACS complex of C. hydrogenoformans | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | Authors: | Ruickoldt, J, Jeoung, J.-H, Basak, Y, Domnik, L, Dobbek, H. | | Deposit date: | 2022-04-13 | | Release date: | 2022-11-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | On the Kinetics of CO2 Reduction by Ni, Fe-CO Dehydrogenases
ACS Catal., 2022
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4Q32
 | | Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91 | | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, N-(naphthalen-2-yl)-2-[2-(pyridin-2-yl)-1H-benzimidazol-1-yl]acetamide | | Authors: | Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Gu, M, Zhang, M, Mandapati, K, Gollapalli, D.R, Gorla, S.K, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2014-04-10 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.788 Å) | | Cite: | Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and C91
To be Published
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5UFJ
 | | Crystal Structure of Carbonmonoxy Hemoglobin S (Liganded Sickle Cell Hemoglobin) Complexed with GBT Compound 6 | | Descriptor: | 5-[(imidazo[1,2-a]pyridin-8-yl)methoxy]-2-methoxypyridine-4-carbaldehyde, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | | Authors: | Partridge, J.R, Choy, R.M, Li, Z, Metcalf, B. | | Deposit date: | 2017-01-04 | | Release date: | 2017-02-22 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.
ACS Med Chem Lett, 8, 2017
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4QJ4
 | | Structure of a fragment of human phospholipase C-beta3 delta472-569, bound to IP3 and in complex with Galphaq | | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | Authors: | Lyon, A.M, Tesmer, J.J.G. | | Deposit date: | 2014-06-03 | | Release date: | 2014-10-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Molecular mechanisms of phospholipase C beta 3 autoinhibition.
Structure, 22, 2014
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4B7U
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2Q3B
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1TIQ
 | | Crystal Structure of an Acetyltransferase (PaiA) in complex with CoA and DTT from Bacillus subtilis, Northeast Structural Genomics Target SR64. | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, COENZYME A, Protease synthase and sporulation negative regulatory protein PAI 1, ... | | Authors: | Forouhar, F, Lee, I, Shen, J, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-06-02 | | Release date: | 2004-07-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase.
J.Biol.Chem., 280, 2005
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2VNK
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6MYQ
 | | Avian mitochondrial complex II with ferulenol bound | | Descriptor: | (~{Z})-2-oxidanylbut-2-enedioic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, ... | | Authors: | Berry, E.A, Huang, L.-S. | | Deposit date: | 2018-11-02 | | Release date: | 2019-11-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
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4BZY
 | | Crystal structure of human glycogen branching enzyme (GBE1) | | Descriptor: | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME | | Authors: | Froese, D.S, Krojer, T, Goubin, S, Strain-Damerell, C, Mahajan, P, von Delft, F, Burgess-Brown, N, Bountra, C, Arrowsmith, C.H, Edwards, A, Yue, W.W. | | Deposit date: | 2013-07-30 | | Release date: | 2013-09-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural Basis of Glycogen Branching Enzyme Deficiency and Pharmacologic Rescue by Rational Peptide Design.
Hum.Mol.Genet., 24, 2015
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5TQM
 | | Cinnamoyl-CoA Reductase 1 from Sorghum bicolor in complex with NADP+ | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cinnamoyl-CoA Reductase, GLYCEROL, ... | | Authors: | Sattler, S.A, Kang, C.H. | | Deposit date: | 2016-10-24 | | Release date: | 2017-04-26 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases.
Plant Physiol., 173, 2017
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