2Q3B

1.8 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS

Summary for 2Q3B

• Entry DOI: 10.2210/pdb2q3b/pdb
• Related: 2Q3C 2Q3D
• Descriptor: Cysteine synthase A, CHLORIDE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: mycobacterium tuberculosis, pyridoxal-5'-phosphate, sulphur metabolism, cysteine biosynthesis, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 33804.16

Authors

Schneider, G.,Schnell, R. (deposition date: 2007-05-30, release date: 2007-06-12, Last modification date: 2023-11-15)

• Primary citation: Schnell, R.,Oehlmann, W.,Singh, M.,Schneider, G.; Structural Insights into Catalysis and Inhibition of O-Acetylserine Sulfhydrylase from Mycobacterium tuberculosis: CRYSTAL STRUCTURES OF THE ENZYME {alpha}-AMINOACRYLATE INTERMEDIATE AND AN ENZYME-INHIBITOR COMPLEX.; J.Biol.Chem., 282:23473-23481, 2007; PubMed: 17567578; DOI: 10.1074/jbc.M703518200

Experimental method

X-RAY DIFFRACTION (1.8 Å)