4S2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4s2y by Molmil](/molmil-images/mine/4s2y) | Structure of E. coli RppH bound to RNA and three magnesium ions | Descriptor: | CHLORIDE ION, MAGNESIUM ION, RNA (5'-R(*(APC)*GP*U)-3'), ... | Authors: | Vasilyev, N, Serganov, A. | Deposit date: | 2015-01-23 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of RNA Complexes with the Escherichia coli RNA Pyrophosphohydrolase RppH Unveil the Basis for Specific 5'-End-dependent mRNA Decay. J.Biol.Chem., 290, 2015
|
|
4TSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tsx by Molmil](/molmil-images/mine/4tsx) | |
5YLA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yla by Molmil](/molmil-images/mine/5yla) | |
4TQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tqh by Molmil](/molmil-images/mine/4tqh) | Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid | Descriptor: | 1,2-ETHANEDIOL, Transthyretin, [(9H-fluoren-9-ylideneamino)oxy]acetic acid | Authors: | Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A. | Deposit date: | 2014-06-11 | Release date: | 2015-06-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.511 Å) | Cite: | X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors. J Enzyme Inhib Med Chem, 2015
|
|
4TRK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4trk by Molmil](/molmil-images/mine/4trk) | Structure of C. elegans HIM-3 | Descriptor: | C. elegans HIM-3 | Authors: | Rosenberg, S.C, Corbett, K.D. | Deposit date: | 2014-06-17 | Release date: | 2014-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins. Dev.Cell, 31, 2014
|
|
5YGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ygi by Molmil](/molmil-images/mine/5ygi) | |
4RNC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rnc by Molmil](/molmil-images/mine/4rnc) | Crystal structure of an esterase RhEst1 from Rhodococcus sp. ECU1013 | Descriptor: | Esterase, PHOSPHATE ION | Authors: | Dou, S, Kong, X.D, Xu, J.H, Zhou, J. | Deposit date: | 2014-10-23 | Release date: | 2015-10-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Substrate channel evolution of an esterase for the synthesis of Cilastatin CATALYSIS SCIENCE AND TECHNOLOGY, 5, 2015
|
|
7OR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7or4 by Molmil](/molmil-images/mine/7or4) | Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B142 | Descriptor: | Dipeptidyl peptidase 8, methyl 3-[4-[(4-bromophenyl)methyl]piperazin-1-yl]carbonyl-5-[(2-ethyl-2-methanoyl-butanoyl)amino]benzoate, trimethylamine oxide | Authors: | Ross, B, Huber, R. | Deposit date: | 2021-06-04 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7OZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oz7 by Molmil](/molmil-images/mine/7oz7) | Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, L84 | Descriptor: | Dipeptidyl peptidase 8, trimethylamine oxide, ~{N}-[3-[[4-[(4-bromophenyl)methyl]piperazin-1-yl]methyl]phenyl]-2-ethyl-2-methanoyl-butanamide | Authors: | Ross, B, Huber, R. | Deposit date: | 2021-06-26 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
4RYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ryw by Molmil](/molmil-images/mine/4ryw) | |
7OW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ow0 by Molmil](/molmil-images/mine/7ow0) | |
7OS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7os9 by Molmil](/molmil-images/mine/7os9) | Crystal Structure of Domain Swapped Trp Repressor V58I Variant with purification tag | Descriptor: | IMIDAZOLE, Trp operon repressor | Authors: | Sprenger, J, Lawson, C.L, Lo Leggio, L, Von Wachenfeldt, C, Carey, J. | Deposit date: | 2021-06-08 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan. Acta Crystallogr.,Sect.F, 77, 2021
|
|
4S2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4s2v by Molmil](/molmil-images/mine/4s2v) | E. coli RppH structure, KI soak | Descriptor: | ACETATE ION, CALCIUM ION, IODIDE ION, ... | Authors: | Vasilyev, N, Serganov, A. | Deposit date: | 2015-01-23 | Release date: | 2015-02-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of RNA Complexes with the Escherichia coli RNA Pyrophosphohydrolase RppH Unveil the Basis for Specific 5'-End-dependent mRNA Decay. J.Biol.Chem., 290, 2015
|
|
7ONU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7onu by Molmil](/molmil-images/mine/7onu) | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase type-2, MAGNESIUM ION, Mitochondrial Precursor tRNA-Tyr, ... | Authors: | Bhatta, A, Dienemann, C, Cramer, P, Hillen, H.S. | Deposit date: | 2021-05-26 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of RNA processing by human mitochondrial RNase P. Nat.Struct.Mol.Biol., 28, 2021
|
|
4U0U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u0u by Molmil](/molmil-images/mine/4u0u) | Wild type eukaryotic fic domain containing protein with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION, ... | Authors: | Cole, A.R, Bunney, T.D, Katan, M. | Deposit date: | 2014-07-14 | Release date: | 2014-12-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions. Structure, 22, 2014
|
|
5YLK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ylk by Molmil](/molmil-images/mine/5ylk) | Complex structure of GH 113 family beta-1,4-mannanase with mannobiose | Descriptor: | beta-1,4-mannanase, beta-D-mannopyranose, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose | Authors: | Jiang, Z.Q, You, X, Yang, S.Q, Huang, P, Ma, J.W. | Deposit date: | 2017-10-17 | Release date: | 2018-06-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural insights into the catalytic mechanism of a novel glycoside hydrolase family 113 beta-1,4-mannanase fromn Amphibacillus xylanus J. Biol. Chem., 293, 2018
|
|
4UAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4uaf by Molmil](/molmil-images/mine/4uaf) | |
5YKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ykl by Molmil](/molmil-images/mine/5ykl) | |
5YKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ykq by Molmil](/molmil-images/mine/5ykq) | |
4U04
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u04 by Molmil](/molmil-images/mine/4u04) | Structure of a eukaryotic fic domain containing protein | Descriptor: | Adenosine monophosphate-protein transferase FICD, D(-)-TARTARIC ACID, TETRAETHYLENE GLYCOL | Authors: | Cole, A.R, Bunney, T.D, Katan, M. | Deposit date: | 2014-07-11 | Release date: | 2014-12-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions. Structure, 22, 2014
|
|
7P3S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p3s by Molmil](/molmil-images/mine/7p3s) | Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 12 | Descriptor: | GLYCEROL, Histone deacetylase, POTASSIUM ION, ... | Authors: | Shaik, T.B, Romier, C. | Deposit date: | 2021-07-08 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.546 Å) | Cite: | Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis. Eur.J.Med.Chem., 225, 2021
|
|
4U06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u06 by Molmil](/molmil-images/mine/4u06) | Structure of Leptospira interrogans LRR protein LIC10831 | Descriptor: | CHLORIDE ION, LIC10831, ZINC ION | Authors: | Shepard, W, Saul, F.A, Haouz, A, Picardeau, M. | Deposit date: | 2014-07-11 | Release date: | 2015-06-03 | Last modified: | 2015-06-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of a novel subfamily of leucine-rich repeat proteins from the human pathogen Leptospira interrogans. Acta Crystallogr.,Sect.D, 71, 2015
|
|
5YKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ykk by Molmil](/molmil-images/mine/5ykk) | |
5Y0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y0h by Molmil](/molmil-images/mine/5y0h) | Solution structure of arenicin-3 derivative N6 | Descriptor: | N6 | Authors: | Liu, X.H, Wang, J.H. | Deposit date: | 2017-07-17 | Release date: | 2017-07-26 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis Sci Rep, 7, 2017
|
|
5Y0U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y0u by Molmil](/molmil-images/mine/5y0u) | The solution structure of AEBP2 C2H2 zinc fingers | Descriptor: | ZINC ION, Zinc finger protein AEBP2 | Authors: | Sun, A, Shi, Y, Wu, J. | Deposit date: | 2017-07-18 | Release date: | 2018-08-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4. Protein Cell, 9, 2018
|
|