PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

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4PPX	DNA Polymerase Beta E295K with Spiroiminodihydantoin in Templating Position Descriptor: 5'-D(*CP*CP*GP*AP*CP*(SDH)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*G)-3', ... Authors: Eckenroth, B.E, Doublie, S. Deposit date: 2014-02-27 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Crystal Structure of DNA Polymerase beta with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position. Biochemistry, 53, 2014
4PR5	Crystal structure of a HLA-B*35:01-HPVG-D5 Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, HLA class I histocompatibility antigen, ... Authors: Yu Chih, L, Rossjohn, J, Gras, S. Deposit date: 2014-03-05 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
4PRI	Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex Descriptor: Beta-2-microglobulin, CHLORIDE ION, Epstein-Barr nuclear antigen 1, ... Authors: Yu Chih, L, Rossjohn, J, Gras, S. Deposit date: 2014-03-05 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
4NS5	Crystal structure of human BS69 Bromo-Zinc finger-PWWP Descriptor: ZINC ION, Zinc finger MYND domain-containing protein 11 Authors: Wang, J.C, Qin, S, Li, F.D, Li, S, Zhang, W, Wu, J.H, Shi, Y.Y. Deposit date: 2013-11-28 Release date: 2014-04-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding. Cell Res., 24, 2014
3TX8	Crystal structure of a succinyl-diaminopimelate desuccinylase (ArgE) from Corynebacterium glutamicum ATCC 13032 at 2.97 A resolution Descriptor: CHLORIDE ION, PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase Authors: Joint Center for Structural Genomics (JCSG), Brunger, A.T, Terwilliger, T.C, Read, R.J, Adams, P.D, Levitt, M, Schroder, G.F. Deposit date: 2011-09-22 Release date: 2011-10-26 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.972 Å) Cite: Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum. Acta Crystallogr.,Sect.D, 68, 2012
4PTK	Crystal structure of Staphylococcal IMPase-I complex with 3Mg2+ and Phosphate Descriptor: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... Authors: Dutta, A, Bhattacharyya, S, Dutta, D, Das, A.K. Deposit date: 2014-03-11 Release date: 2014-10-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Structural elucidation of the binding site and mode of inhibition of Li(+) and Mg(2+) in inositol monophosphatase. Febs J., 281, 2014
4NYN	Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1 Descriptor: MANGANESE (II) ION, Ribonuclease HI Authors: You, D.J, Angkawidjaja, C, Koga, Y, Kanaya, S. Deposit date: 2013-12-11 Release date: 2014-02-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1 To be Published
4NF7	Crystal structure of the GH5 family catalytic domain of Endo-1,4-beta-glucanase Cel5C from Butyrivibrio proteoclasticus. Descriptor: Endo-1,4-beta-glucanase Cel5C Authors: Lott, J.S, Colbert, D.A. Deposit date: 2013-10-30 Release date: 2014-11-05 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.111 Å) Cite: Structural and functional characterisation of endo-1,4-beta-glucanase Cel5C from bovine rumen microbe Butyrivibrio proteoclasticus To be Published
3WZW	3-isopropylmalate dehydrogenase from Shewanella oneidensis MR-1 at 580MPa - complex with IPM and Mg Descriptor: 3-ISOPROPYLMALIC ACID, 3-isopropylmalate dehydrogenase, MAGNESIUM ION Authors: Nagae, T, Watanabe, N. Deposit date: 2014-10-08 Release date: 2015-10-14 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution To be Published
3X1T	Crystal structure of nucleosome core particle consisting of mouse testis specific histone variants H2aa and H2ba Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A, ... Authors: Sivaraman, P, Kumarevel, T.S. Deposit date: 2014-11-27 Release date: 2015-09-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.808 Å) Cite: Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming Biochem.Biophys.Res.Commun., 464, 2015
4PRA	Crystal structure of a HLA-B*35:01-HPVG-Q5 Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen Authors: Yu Chih, L, Rossjohn, J, Gras, S. Deposit date: 2014-03-05 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
4PRH	Crystal structure of TK3 TCR-HLA-B*35:08-HPVG-D5 complex Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen, ... Authors: Yu Chih, L, Rossjohn, J, Gras, S. Deposit date: 2014-03-05 Release date: 2014-04-30 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
4PZ3	High-resolution crystal structure of the human CD44 hyaluronan binding domain complex with undefined peptides Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CD44 antigen, ... Authors: Liu, L.K, Finzel, B. Deposit date: 2014-03-28 Release date: 2014-09-17 Last modified: 2014-10-15 Method: X-RAY DIFFRACTION (1.083 Å) Cite: High-resolution crystal structures of alternate forms of the human CD44 hyaluronan-binding domain reveal a site for protein interaction. Acta Crystallogr F Struct Biol Commun, 70, 2014
4EWZ	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-04-29 Release date: 2013-05-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.791 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4Q14	Crystal structure of 5-hydroxyisourate hydrolase from Brucella melitensis Descriptor: 5-hydroxyisourate hydrolase, CHLORIDE ION, CITRIC ACID Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2014-04-02 Release date: 2014-05-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of 5-hydroxyisourate hydrolase from Brucella melitensis To be Published
4N8Q	Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase Descriptor: 2-amino-4-fluorobenzoic acid, Anthranilate phosphoribosyltransferase Authors: Castell, A, Cookson, T.V.M, Bulloch, E, Evans, G.L, Baker, E.N, Lott, J.S, Parker, E.J. Deposit date: 2013-10-17 Release date: 2014-04-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
4E6Q	JAK2 kinase (JH1 domain) triple mutant in complex with compound 12 Descriptor: 1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2 Authors: Murray, J.M. Deposit date: 2012-03-15 Release date: 2012-05-30 Last modified: 2012-07-11 Method: X-RAY DIFFRACTION (1.948 Å) Cite: Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. J.Med.Chem., 55, 2012
4EB0	Crystal structure of Leaf-branch compost bacterial cutinase homolog Descriptor: LCC, THIOCYANATE ION Authors: Sulaiman, S, You, D.J, Eiko, K, Koga, Y, Kanaya, S. Deposit date: 2012-03-23 Release date: 2013-03-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of Leaf-branch compost bacterial cutinase homolog To be Published
4Q68	Crystal structure of a N-acetylmuramoyl-L-alanine amidase (BACUNI_02947) from Bacteroides uniformis ATCC 8492 at 1.07 A resolution Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Uncharacterized protein Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2014-04-21 Release date: 2014-05-07 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.07 Å) Cite: Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family. Structure, 22, 2014
4MTY	Structure at 1A resolution of a helical aromatic foldamer-protein complex. Descriptor: 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase 2, GLYCEROL, ... Authors: Ogayone, T, Buratto, J, Langlois D'Estaintot, B, Stupfel, M, Granier, T, Gallois, B, Huc, Y. Deposit date: 2013-09-20 Release date: 2013-12-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1 Å) Cite: Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 a resolution. Angew.Chem.Int.Ed.Engl., 53, 2014
4QCC	Structure of a cube-shaped, highly porous protein cage designed by fusing symmetric oligomeric domains Descriptor: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, peptidyl-prolyl cis-trans isomerase chimera Authors: Lai, Y.-T, Yeates, T.O. Deposit date: 2014-05-10 Release date: 2014-11-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (7.078 Å) Cite: Structure of a designed protein cage that self-assembles into a highly porous cube. Nat Chem, 6, 2014
4MVK	Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide fragment VFFAED Descriptor: Amyloid peptide fragment VFFAED, Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2013-09-24 Release date: 2015-08-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide. Biochem.J., 473, 2016
4QFC	Co-crystal structure of compound 3 (4-hydroxy-6-[2-(7-hydroxy-2-oxo-4-phenyl-2h-chromen-6-yl)ethyl]pyridazin-3(2h)-one) and FAD bound to human DAAO at 2.4A Descriptor: 4-hydroxy-6-[2-(7-hydroxy-2-oxo-4-phenyl-2H-chromen-6-yl)ethyl]pyridazin-3(2H)-one, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Lukacs, C.M, Chun, L. Deposit date: 2014-05-20 Release date: 2014-07-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation. Biosci.Rep., 34, 2014
4EJK	HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment 1F1-N in the outside/top of flap Descriptor: INDOLYLPROPIONIC ACID, Protease, pepstatin Authors: Tiefenbrunn, T, Stout, C.D. Deposit date: 2012-04-06 Release date: 2013-05-01 Last modified: 2018-03-07 Method: X-RAY DIFFRACTION (1.794 Å) Cite: Small molecule regulation of protein conformation by binding in the Flap of HIV protease. Acs Chem.Biol., 8, 2013
4QJM	Crystal structure of human carbonic anhydrase isozyme II with inhibitor Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide, BICINE, ... Authors: Smirnov, A, Manakova, E, Grazulis, S. Deposit date: 2014-06-04 Release date: 2015-04-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases Chemmedchem, 10, 2015

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