8CPV
 
 | | Human apoferritin | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.76 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPS
 | | Human apoferritin | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.82 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPW
 | | Human apoferritin after 405 nm + 488 nm laser exposure in presence of rsEGFP2 | | Descriptor: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | Authors: | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | Deposit date: | 2023-03-03 | | Release date: | 2023-03-15 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (1.79 Å) | | Cite: | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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5IEZ
 | | Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) inhibitors using Structure-Based Design | | Descriptor: | 3-({6-chloro-3-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-7-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1H-indole-2-carbonyl}amino)benzoic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | | Authors: | Zhao, B. | | Deposit date: | 2016-02-25 | | Release date: | 2017-01-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Discovery and biological characterization of potent myeloid cell leukemia-1 inhibitors.
FEBS Lett., 591, 2017
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8FWA
 | | Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography | | Descriptor: | C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ... | | Authors: | Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A. | | Deposit date: | 2023-01-20 | | Release date: | 2023-06-28 | | Last modified: | 2023-07-12 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.
Lab Chip, 23, 2023
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5I5P
 | | Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157) in complex with co-purified 4-hydroxybenzoate | | Descriptor: | BROMIDE ION, DI(HYDROXYETHYL)ETHER, P-HYDROXYBENZOIC ACID, ... | | Authors: | Vetting, M.W, Al Obaidi, N.F, Hogle, S.L, Dupont, C.L, Almo, S.C. | | Deposit date: | 2016-02-15 | | Release date: | 2017-01-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157) in complex with co-purified 4-hydroxybenzoate
To Be Published
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5IK5
 | | Laminin A2LG45 C-form, G6/7 bound. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, CALCIUM ION, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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7D7C
 | | CryoEM structure of gp55-dependent RNA polymerase-promoter open complex | | Descriptor: | DNA (nontemplate strand), DNA (template strand), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Shi, J, Wen, A, Jin, S, Feng, Y. | | Deposit date: | 2020-10-03 | | Release date: | 2021-01-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Transcription activation by a sliding clamp.
Nat Commun, 12, 2021
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1KPS
 | | Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1 | | Descriptor: | Ran-GTPase activating protein 1, SULFATE ION, Ubiquitin-like protein SUMO-1 conjugating enzyme | | Authors: | Bernier-Villamor, V, Sampson, D.A, Matunis, M.J, Lima, C.D. | | Deposit date: | 2002-01-02 | | Release date: | 2002-02-13 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1.
Cell(Cambridge,Mass.), 108, 2002
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7PF1
 | | UVC treated Human apoferritin | | Descriptor: | CHLORIDE ION, Ferritin heavy chain, N-terminally processed, ... | | Authors: | Renault, L, Depelteau, J.S, Briegel, A. | | Deposit date: | 2021-08-11 | | Release date: | 2022-01-26 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | UVC inactivation of pathogenic samples suitable for cryo-EM analysis.
Commun Biol, 5, 2022
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5IK8
 | | Laminin A2LG45 I-form, G6/7 bound. | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ... | | Authors: | Briggs, D.C, Hohenester, E, Campbell, K.P. | | Deposit date: | 2016-03-03 | | Release date: | 2016-08-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
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6LNP
 | | Crystal structure of citrate Biosensor | | Descriptor: | CITRIC ACID, Fusion protein of Green fluorescent protein and Sensor histidine kinase CitA | | Authors: | Wen, Y, Campbell, R. | | Deposit date: | 2019-12-31 | | Release date: | 2020-05-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.993 Å) | | Cite: | High-Performance Intensiometric Direct- and Inverse-Response Genetically Encoded Biosensors for Citrate.
Acs Cent.Sci., 6, 2020
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7X5L
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | DNA (5'-D(*AP*TP*AP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*AP*TP*TP*AP*A)-3'), Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-04 | | Release date: | 2022-06-01 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7X5K
 | | Tir-dsDNA complex, the initial binding state | | Descriptor: | DNA (43-MER), Flax rust resistance protein | | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | | Deposit date: | 2022-03-04 | | Release date: | 2022-06-08 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death.
Cell, 185, 2022
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7NDG
 | | Cryo-EM structure of the ternary complex between Netrin-1, Neogenin and Repulsive Guidance Molecule B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ... | | Authors: | Robinson, R.A, Griffiths, S.C, van de Haar, L.L, Malinauskas, T, van Battum, E.Y, Zelina, P, Schwab, R.A, Karia, D, Malinauskaite, L, Brignani, S, van den Munkhof, M, Dudukcu, O, De Ruiter, A.A, Van den Heuvel, D.M.A, Bishop, B, Elegheert, J, Aricescu, A.R, Pasterkamp, R.J, Siebold, C. | | Deposit date: | 2021-02-01 | | Release date: | 2021-03-31 | | Last modified: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (5.98 Å) | | Cite: | Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Cell, 184, 2021
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6E8L
 | | Crystal Structure of Alkyl hydroperoxidase D (AhpD) from Streptococcus pneumoniae (Strain D39/ NCTC 7466) | | Descriptor: | Alkyl hydroperoxide reductase AhpD | | Authors: | Meng, Y, Davies, J, North, R, Coombes, D, Horne, C, Hampton, M, Dobson, R. | | Deposit date: | 2018-07-30 | | Release date: | 2019-08-28 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-function analyses of alkylhydroperoxidase D fromStreptococcus pneumoniaereveal an unusual three-cysteine active site architecture.
J.Biol.Chem., 295, 2020
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8HW4
 | | Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs | | Descriptor: | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3 | | Authors: | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2022-12-28 | | Release date: | 2023-06-07 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
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8HVH
 | | Cryo-EM structure of ABC transporter ABCC3 | | Descriptor: | ATP-binding cassette sub-family C member 3 | | Authors: | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2022-12-26 | | Release date: | 2023-06-07 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
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8HW2
 | | Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs | | Descriptor: | ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide | | Authors: | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | | Deposit date: | 2022-12-28 | | Release date: | 2023-06-07 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
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7PLM
 | | CryoEM reconstruction of pyruvate ferredoxin oxidoreductase (PFOR) in anaerobic conditions | | Descriptor: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Cherrier, M.V, Vernede, X, Fenel, D, Martin, L, Arragain, B, Neumann, E, Fontecilla Camps, J.C, Schoehn, G, Nicolet, Y. | | Deposit date: | 2021-08-31 | | Release date: | 2022-03-23 | | Last modified: | 2022-04-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy.
Biomolecules, 12, 2022
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6EFX
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2DHN
 | | COMPLEX OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS WITH 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 2.2 A RESOLUTION | | Descriptor: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 7,8-DIHYDRONEOPTERIN ALDOLASE | | Authors: | Hennig, M, D'Arcy, A, Hampele, I.C, Page, M.G.P, Oefner, C.H, Dale, G. | | Deposit date: | 1998-03-31 | | Release date: | 1999-04-20 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus.
Nat.Struct.Biol., 5, 1998
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2E3X
 | | Crystal structure of Russell's viper venom metalloproteinase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, ... | | Authors: | Igarashi, T, Takeda, S. | | Deposit date: | 2006-11-30 | | Release date: | 2007-12-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Crystal structure of RVV-X: an example of evolutionary gain of specificity by ADAM proteinases.
Febs Lett., 581, 2007
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5OYH
 | | crystal structure of the catalytic core of a rhodopsin-guanylyl cyclase with converted specificity in complex with ATPalphaS | | Descriptor: | ADENOSINE-5'-SP-ALPHA-THIO-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ... | | Authors: | Broser, M, Scheib, U, Hegemann, P. | | Deposit date: | 2017-09-09 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.249 Å) | | Cite: | Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 angstrom structure of the adenylyl cyclase domain.
Nat Commun, 9, 2018
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6S63
 | | Dark-adapted structure of Archaerhodopsin-3 obtained from LCP crystals using a thin-film sandwich at room temperature | | Descriptor: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Moraes, I, Judge, P.J, Axford, D, Bada Juarez, J.F, Vinals, J, Watts, A. | | Deposit date: | 2019-07-02 | | Release date: | 2020-07-22 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Two states of a light-sensitive membrane protein captured at room temperature using thin-film sample mounts.
Acta Crystallogr D Struct Biol, 78, 2022
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