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8QKX
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BU of 8qkx by Molmil
Solution structure of a bimolecular quadruplex-duplex hybrid containing a V-shaped loop
Descriptor: DNA (5'-D(*CP*TP*CP*CP*AP*GP*CP*TP*GP*GP*GP*TP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*GP*AP*GP*TP*T)-3')
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-09-18
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Structural Aspects of Split G-Quadruplexes in Quadruplex-Duplex Hybrid Systems
Chemistryselect, 2024
1KF1
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BU of 1kf1 by Molmil
Structure and Packing of Human Telomeric DNA
Descriptor: 5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3, POTASSIUM ION
Authors:Parkinson, G.N, Lee, M.P.H, Neidle, S.
Deposit date:2001-11-19
Release date:2002-05-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature, 417, 2002
4Q9Q
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BU of 4q9q by Molmil
Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab
Descriptor: (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ...
Authors:Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2014-05-01
Release date:2014-06-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4WO3
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BU of 4wo3 by Molmil
THE SECOND C-KIT DNA QUADRUPLEX CRYSTAL STRUCTURE
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
Authors:Wei, D, Neidle, S.
Deposit date:2014-10-15
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:THE SECOND C-KIT1 DNA QUADRUPLEX CRYSTAL STRUCTURE
TO BE PUBLISHED
4KZD
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BU of 4kzd by Molmil
Crystal structure of an RNA aptamer in complex with fluorophore and Fab
Descriptor: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4KZE
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BU of 4kze by Molmil
Crystal structure of an RNA aptamer in complex with Fab
Descriptor: BL3-6 Fab antibody, heavy chain, light chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
5VHA
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BU of 5vha by Molmil
DHX36 with an N-terminal truncation
Descriptor: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Authors:Chen, M, Ferre-D'Amare, A.
Deposit date:2017-04-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
Nature, 558, 2018
5VHD
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BU of 5vhd by Molmil
DHX36 with an N-terminal truncation bound to ADP-AlF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DEAH (Asp-Glu-Ala-His) box polypeptide 36, TETRAFLUOROALUMINATE ION
Authors:Chen, M, Ferre-D'Amare, A.
Deposit date:2017-04-13
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
Nature, 558, 2018
5VHC
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BU of 5vhc by Molmil
DHX36 with an N-terminal truncation bound to ADP-BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DEAH (Asp-Glu-Ala-His) box polypeptide 36, ...
Authors:Chen, M, Ferre-D'Amare, A.
Deposit date:2017-04-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
Nature, 558, 2018
2A5P
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BU of 2a5p by Molmil
Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct.
Descriptor: 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2A5R
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BU of 2a5r by Molmil
Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.
Descriptor: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
4WO2
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BU of 4wo2 by Molmil
CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
Authors:wei, D, parkinson, g.n, neidle, s.
Deposit date:2014-10-15
Release date:2014-10-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT-1 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
TO BE PUBLISHED
1X0F
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BU of 1x0f by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D(AUF1) with telomeric DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.
J.Biol.Chem., 280, 2005
4KI2
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BU of 4ki2 by Molmil
Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA
Descriptor: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor
Authors:Feklistov, A, Darst, S.A.
Deposit date:2013-05-01
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes.
Acta Crystallogr.,Sect.F, 69, 2013
1LVS
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BU of 1lvs by Molmil
THE SOLUTION STRUCTURE OF D(G4T4G3)2
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*G)-3'
Authors:Crnugelj, M, Hud, N.V, Plavec, J.
Deposit date:2002-05-29
Release date:2002-07-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of d(G(4)T(4)G(3))(2): a bimolecular G-quadruplex with a novel fold.
J.Mol.Biol., 320, 2002
6H5R
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BU of 6h5r by Molmil
Structure of the complex of a human telomeric DNA with bis(1-butyl-3-methyl-imidazole-2-ylidene) gold(I)
Descriptor: Human Telomeric DNA, POTASSIUM ION, STRONTIUM ION, ...
Authors:Bazzicalupi, C, Gratteri, P, Papi, F.
Deposit date:2018-07-25
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis.
Dalton Trans, 47, 2018
1JRN
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BU of 1jrn by Molmil
Orthorhombic form of Oxytricha telomeric DNA at 2.0A
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Haider, S.M, Parkinson, G, Neidle, S.
Deposit date:2001-08-14
Release date:2002-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.
J.Mol.Biol., 320, 2002
1JPQ
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BU of 1jpq by Molmil
Crystal Structure of the Oxytricha Telomeric DNA at 1.6A
Descriptor: 5'-D(*GP*GP*GP*GP*(BRU)P*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Haider, S.M, Parkinson, G, Neidle, S.
Deposit date:2001-08-03
Release date:2002-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.
J.Mol.Biol., 320, 2002
5CCW
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BU of 5ccw by Molmil
Structure of the complex of a human telomeric DNA with Au(caffein-2-ylidene)2
Descriptor: Au(caffein-2-ylidene)2, POTASSIUM ION, human telomeric DNA
Authors:Ferraroni, M, Bazzicalupi, C, Gratteri, P, Messori, L, Papi, F.
Deposit date:2015-07-02
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation.
Angew.Chem.Int.Ed.Engl., 55, 2016
6TZS
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BU of 6tzs by Molmil
A DNA i-motif/duplex hybrid
Descriptor: DNA (5'-D(*CP*CP*AP*GP*GP*CP*TP*GP*(CBR)P*AP*A)-3')
Authors:Chu, B, Paukstelis, P.J.
Deposit date:2019-08-13
Release date:2019-10-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A DNA G-quadruplex/i-motif hybrid.
Nucleic Acids Res., 47, 2019
2WCT
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BU of 2wct by Molmil
human SARS coronavirus unique domain (triclinic form)
Descriptor: NON-STRUCTURAL PROTEIN 3
Authors:Tan, J, Vonrhein, C, Smart, O.S, Bricogne, G, Bollati, M, Hansen, G, Mesters, J.R, Hilgenfeld, R.
Deposit date:2009-03-16
Release date:2009-05-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Plos Pathog., 5, 2009
1WTB
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BU of 1wtb by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D (AUF1) with telomere DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2004-11-22
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
J.Biol.Chem., 280, 2005
7Q48
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BU of 7q48 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*UP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-10-29
Release date:2022-11-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
To Be Published
7QA2
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BU of 7qa2 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*GP*GP*GP*GP*UP*GP*GP*GP*AP*GP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Falk, T, Jurt, S, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published
7Q6L
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BU of 7q6l by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*AP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-08
Release date:2022-11-16
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published

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