6H5R

Structure of the complex of a human telomeric DNA with bis(1-butyl-3-methyl-imidazole-2-ylidene) gold(I)

Summary for 6H5R

• Entry DOI: 10.2210/pdb6h5r/pdb
• Descriptor: Human Telomeric DNA, POTASSIUM ION, STRONTIUM ION, ... (5 entities in total)
• Functional Keywords: drug-dna complex, g quadruplex, dna
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 9651.25

Authors

Bazzicalupi, C.,Gratteri, P.,Papi, F. (deposition date: 2018-07-25, release date: 2019-01-30, Last modification date: 2024-01-17)

• Primary citation: Guarra, F.,Marzo, T.,Ferraroni, M.,Papi, F.,Bazzicalupi, C.,Gratteri, P.,Pescitelli, G.,Messori, L.,Biver, T.,Gabbiani, C.; Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis.; Dalton Trans, 47:16132-16138, 2018; PubMed: 30378627; DOI: 10.1039/c8dt03607a

Experimental method

X-RAY DIFFRACTION (2 Å)