5CCW
Structure of the complex of a human telomeric DNA with Au(caffein-2-ylidene)2
Summary for 5CCW
| Entry DOI | 10.2210/pdb5ccw/pdb |
| Descriptor | human telomeric DNA, POTASSIUM ION, Au(caffein-2-ylidene)2, ... (4 entities in total) |
| Functional Keywords | drug-dna complex, g-quadruplex, drug/dna |
| Biological source | Homo sapiens |
| Total number of polymer chains | 1 |
| Total formula weight | 9206.09 |
| Authors | Ferraroni, M.,Bazzicalupi, C.,Gratteri, P.,Messori, L.,Papi, F. (deposition date: 2015-07-02, release date: 2016-03-16, Last modification date: 2024-01-10) |
| Primary citation | Bazzicalupi, C.,Ferraroni, M.,Papi, F.,Massai, L.,Bertrand, B.,Messori, L.,Gratteri, P.,Casini, A. Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation. Angew.Chem.Int.Ed.Engl., 55:4256-4259, 2016 Cited by PubMed: 26929051DOI: 10.1002/anie.201511999 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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