PDB: 1406 resultsInfo pagesStatus searchChemie searchBIRD

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1CDC	CD2, N-TERMINAL DOMAIN (1-99), TRUNCATED FORM Descriptor: CD2 Authors: Murray, A.J, Barclay, A.N, Brady, R.L. Deposit date: 1995-05-23 Release date: 1995-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: One sequence, two folds: a metastable structure of CD2. Proc.Natl.Acad.Sci.USA, 92, 1995
1A7P	FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL Descriptor: ACETIC ACID, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) Authors: Marks, C, Henrick, K, Winter, G. Deposit date: 1998-03-16 Release date: 1998-04-29 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.01 Å) Cite: X-Ray Structures of D1.3 Fv Mutants To be Published
1A8J	IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG) COMPLEX WITH ASPARTAME Descriptor: IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG), N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER Authors: Edmundson, A.B, Manion, C.V. Deposit date: 1998-03-26 Release date: 1998-06-17 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Treatment of osteoarthritis with aspartame. Clin.Pharmacol.Ther., 63, 1998
1AC6	CRYSTAL STRUCTURE OF A VARIABLE DOMAIN MUTANT OF A T-CELL RECEPTOR ALPHA CHAIN Descriptor: T-CELL RECEPTOR ALPHA Authors: Li, H.-M, Mariuzza, R.A. Deposit date: 1997-02-13 Release date: 1998-02-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association. J.Mol.Biol., 269, 1997
1A7Q	FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) Authors: Marks, C, Henrick, K, Winter, G. Deposit date: 1998-03-16 Release date: 1998-04-29 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2 Å) Cite: X-Ray Structures of D1.3 Fv Mutants To be Published
1AH1	CTLA-4, NMR, 20 STRUCTURES Descriptor: CTLA-4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Metzler, W.J, Bajorath, J, Fenderson, W, Shaw, S.-Y, Peach, R, Constantine, K.L, Naemura, J, Leytze, G, Lavoie, T.B, Mueller, L, Linsley, P.S. Deposit date: 1997-04-11 Release date: 1998-04-15 Last modified: 2020-07-29 Method: SOLUTION NMR Cite: Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28. Nat.Struct.Biol., 4, 1997
1CDB	STRUCTURE OF THE GLYCOSYLATED ADHESION DOMAIN OF HUMAN T LYMPHOCYTE GLYCOPROTEIN CD2 Descriptor: CD2 Authors: Wyss, D.F, Withka, J.M, Recny, M.A, Wagner, G. Deposit date: 1993-09-15 Release date: 1994-01-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2. Structure, 1, 1993
6V3P	The BIgI domain of beta protein from S. agalactiae bound to CEACAM1 Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, IgA FC receptor, ... Authors: Bonsor, D.A, McCarthy, A.J. Deposit date: 2019-11-26 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors. Embo J., 40, 2021
1A7O	FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) Authors: Marks, C, Henrick, K, Winter, G. Deposit date: 1998-03-16 Release date: 1998-04-29 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2 Å) Cite: X-Ray Structures of D1.3 Fv Mutants To be Published
1A6U	B1-8 FV FRAGMENT Descriptor: B1-8 FV (HEAVY CHAIN), B1-8 FV (LIGHT CHAIN) Authors: Simon, T, Henrick, K, Hirshberg, M, Winter, G. Deposit date: 1998-03-03 Release date: 1998-05-27 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-Ray Structures of Fv Fragment and its (4-Hydroxy-3-Nitrophenyl)Acetate Complex of Murine B1-8 Antibody To be Published
1CD8	CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION Descriptor: SULFATE ION, T CELL CORECEPTOR CD8 Authors: Leahy, D.J, Axel, R, Hendrickson, W.A. Deposit date: 1992-01-16 Release date: 1994-01-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution. Cell(Cambridge,Mass.), 68, 1992
1B88	V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN Descriptor: T CELL RECEPTOR V-ALPHA DOMAIN Authors: Plaksin, D, Chacko, S, Navaza, J, Margulies, D.H, Padlan, E.A. Deposit date: 1999-02-09 Release date: 1999-02-16 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing. J.Mol.Biol., 289, 1999
5X8M	PD-L1 in complex with durvalumab Descriptor: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain Authors: Heo, Y.S, Lee, H.T. Deposit date: 2017-03-03 Release date: 2017-08-16 Method: X-RAY DIFFRACTION (2.661 Å) Cite: Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
5X8L	PD-L1 in complex with atezolizumab Descriptor: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain Authors: Heo, Y.S, Lee, H.T. Deposit date: 2017-03-03 Release date: 2017-08-16 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7, 2017
5XJ3	Complex structure of ipilimumab-scFv and CTLA-4 Descriptor: Cytotoxic T-lymphocyte protein 4, ipilimumab-VH, ipilimumab-VL Authors: He, M, Chai, Y, Qi, J, Tong, Z, Tan, S, Gao, G.F. Deposit date: 2017-04-29 Release date: 2018-04-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies Oncotarget, 8, 2017
5XOF	Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I Descriptor: N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Nitric oxide synthase, ... Authors: Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, H, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. Deposit date: 2017-05-28 Release date: 2017-10-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.963 Å) Cite: Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor. J. Biol. Chem., 292, 2017
5XAX	Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta4 subunit explain its role in cell-cell adhesion Descriptor: GLYCEROL, Sodium channel subunit beta-4 Authors: Shimizu, H, Yokoyama, S. Deposit date: 2017-03-15 Release date: 2017-07-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.903 Å) Cite: Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta 4 subunit explain its role in cell-cell adhesion J. Biol. Chem., 292, 2017
5XAW	Parallel homodimer structures of voltage-gated sodium channel beta4 for cell-cell adhesion Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GLYCEROL, Sodium channel subunit beta-4, ... Authors: Shimizu, H, Yokoyama, S. Deposit date: 2017-03-15 Release date: 2017-07-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.101 Å) Cite: Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta 4 subunit explain its role in cell-cell adhesion J. Biol. Chem., 292, 2017
5XO2	Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II Descriptor: N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B Authors: Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, S, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. Deposit date: 2017-05-25 Release date: 2017-10-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.201 Å) Cite: Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor. J. Biol. Chem., 292, 2017
5XP1	Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 6 Descriptor: Immunoglobulin kappa variable 1D-33 Authors: Mine, S, Nakamura, T, Uegaki, K, Hamada, D. Deposit date: 2017-05-31 Release date: 2017-08-02 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI FEBS J., 284, 2017
5XPV	Structure of the V domain of amphioxus IgVJ-C2 Descriptor: amphioxus IgVJ-C2 Authors: Chen, R, Qi, J, Zhang, N, Zhang, L, Yao, S, Wu, Y, Jiang, B, Wang, Z, Yuan, H, Zhang, Q, Xia, C. Deposit date: 2017-06-05 Release date: 2018-04-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily. J. Immunol., 200, 2018
5YD4	Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation T6A) Descriptor: Epitope peptide (mutation T6A), SULFATE ION, scFv 4B08 Authors: Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. Deposit date: 2017-09-11 Release date: 2018-06-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody J. Biochem., 164, 2018
5XXY	Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A Descriptor: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab Authors: Zhou, A, Zhang, F. Deposit date: 2017-07-05 Release date: 2017-09-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab. Oncotarget, 8, 2017
5YD5	Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation N3A) Descriptor: Peptide epitope (mutation N3A), SULFATE ION, scFv 4B08 Authors: Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. Deposit date: 2017-09-11 Release date: 2018-06-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody J. Biochem., 164, 2018
5WT9	Complex structure of PD-1 and nivolumab-Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Nivolumab, Light Chain of Nivolumab, ... Authors: Tan, S, Zhang, H, Chai, Y, Song, H, Tong, Z, Wang, Q, Qi, J, Wong, G, Zhu, X, Liu, W.J, Gao, S, Wang, Z, Shi, Y, Yang, F, Gao, G.F, Yan, J. Deposit date: 2016-12-10 Release date: 2017-02-15 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.401 Å) Cite: An unexpected N-terminal loop in PD-1 dominates binding by nivolumab. Nat Commun, 8, 2017

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