7FGQ
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3B3P
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![BU of 3b3p by Molmil](/molmil-images/mine/3b3p) | Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine, ... | Authors: | Igarashi, J, Li, H, Poulos, T.L. | Deposit date: | 2007-10-22 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors. J.Med.Chem., 52, 2009
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7EVN
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![BU of 7evn by Molmil](/molmil-images/mine/7evn) | The cryo-EM structure of the DDX42-SF3b complex | Descriptor: | ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2021-05-21 | Release date: | 2022-08-03 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into branch site proofreading by human spliceosome Nat.Struct.Mol.Biol., 2024
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7FB9
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![BU of 7fb9 by Molmil](/molmil-images/mine/7fb9) | Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1) | Descriptor: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Baek, Y, Ha, N.-C. | Deposit date: | 2021-07-08 | Release date: | 2022-10-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation. Commun Biol, 5, 2022
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7FDY
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![BU of 7fdy by Molmil](/molmil-images/mine/7fdy) | Structure of OmpF1 | Descriptor: | Porin OmpF, ZINC ION | Authors: | Jeong, W.J, Song, W.J. | Deposit date: | 2021-07-18 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Design and directed evolution of noncanonical beta-stereoselective metalloglycosidases. Nat Commun, 13, 2022
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2JMX
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![BU of 2jmx by Molmil](/molmil-images/mine/2jmx) | OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase | Descriptor: | ATP synthase O subunit, mitochondrial, ATP synthase subunit alpha heart isoform | Authors: | Carbajo, R.J, Neuhaus, D, Kellas, F.A, Yang, J, Runswick, M.J, Montgomery, M.G, Walker, J.E. | Deposit date: | 2006-12-12 | Release date: | 2007-04-24 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | How the N-terminal Domain of the OSCP Subunit of Bovine F(1)F(o)-ATP Synthase Interacts with the N-terminal Region of an Alpha Subunit J.Mol.Biol., 368, 2007
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2PSQ
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3B78
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![BU of 3b78 by Molmil](/molmil-images/mine/3b78) | Structure of the eEF2-ExoA(R551H)-NAD+ complex | Descriptor: | Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Jorgensen, R, Merrill, A.R. | Deposit date: | 2007-10-30 | Release date: | 2008-06-17 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The nature and character of the transition state for the ADP-ribosyltransferase reaction. Embo Rep., 9, 2008
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3B97
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![BU of 3b97 by Molmil](/molmil-images/mine/3b97) | Crystal Structure of human Enolase 1 | Descriptor: | Alpha-enolase, MAGNESIUM ION, SULFATE ION | Authors: | Kang, H.J, Jung, S.K, Kim, S.J, Chung, S.J. | Deposit date: | 2007-11-02 | Release date: | 2008-09-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme. Acta Crystallogr.,Sect.D, 64, 2008
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3BA1
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![BU of 3ba1 by Molmil](/molmil-images/mine/3ba1) | Structure of hydroxyphenylpyruvate reductase from coleus blumei | Descriptor: | Hydroxyphenylpyruvate reductase | Authors: | Janiak, V, Klebe, G, Petersen, M, Heine, A. | Deposit date: | 2007-11-07 | Release date: | 2008-11-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth. Acta Crystallogr.,Sect.D, 66, 2010
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2PVK
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![BU of 2pvk by Molmil](/molmil-images/mine/2pvk) | Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | Descriptor: | 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha | Authors: | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | Deposit date: | 2007-05-09 | Release date: | 2008-05-13 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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3KLE
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![BU of 3kle by Molmil](/molmil-images/mine/3kle) | Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA | Descriptor: | DNA (25-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(2DA))-3'), GLYCEROL, ... | Authors: | Tu, X, Das, K, Sarafianos, S.G, Arnold, E. | Deposit date: | 2009-11-07 | Release date: | 2010-09-22 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of HIV-1 resistance to AZT by excision. Nat.Struct.Mol.Biol., 17, 2010
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2PVY
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7FCV
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![BU of 7fcv by Molmil](/molmil-images/mine/7fcv) | Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana | Descriptor: | PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1 | Authors: | Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L. | Deposit date: | 2021-07-15 | Release date: | 2022-11-09 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis. Nat Commun, 13, 2022
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2JRR
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![BU of 2jrr by Molmil](/molmil-images/mine/2jrr) | Solution NMR Structure of Q5LLS5 from Silicibacter pomeroyi. Northeast Structural Genomics Consortium target SiR90 | Descriptor: | Uncharacterized protein | Authors: | Swapna, G.V.T, Tejero, R, Jiang, M, Cunningham, K, Maglaqui, M, Owens, L, Liu, J, Wang, H, Acton, T.B, Xiao, R, Baran, M.C, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-28 | Release date: | 2007-07-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of Q5LLS5 from Silicibacter pomeroyi. To be Published
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2JNT
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![BU of 2jnt by Molmil](/molmil-images/mine/2jnt) | Structure of Bombyx mori Chemosensory Protein 1 in Solution | Descriptor: | Chemosensory protein CSP1 | Authors: | Jansen, S, Zidek, L, Chmelik, J, Novak, P, Padrta, P, Picimbon, J, Lofstedt, C, Sklenar, V. | Deposit date: | 2007-02-02 | Release date: | 2007-11-20 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structure of Bombyx mori chemosensory protein 1 in solution Arch.Insect Biochem.Physiol., 66, 2007
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3KNQ
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7EWH
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![BU of 7ewh by Molmil](/molmil-images/mine/7ewh) | Crystal structure of human PHGDH in complex with Homoharringtonine | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, D-3-phosphoglycerate dehydrogenase | Authors: | Hsieh, C.H, Cheng, Y.S, Lee, Y.S, Huang, H.C, Juan, H.F. | Deposit date: | 2021-05-25 | Release date: | 2022-12-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma. Biomed Pharmacother, 166, 2023
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2PZR
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3KP2
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3BFP
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![BU of 3bfp by Molmil](/molmil-images/mine/3bfp) | Crystal Structure of apo-PglD from Campylobacter jejuni | Descriptor: | Acetyltransferase, CITRATE ANION | Authors: | Rangarajan, E.S, Watson, D.C, Leclerc, S, Proteau, A, Cygler, M, Matte, A, Young, N.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2007-11-22 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure and Active Site Residues of PglD, an N-Acetyltransferase from the Bacillosamine Synthetic Pathway Required for N-Glycan Synthesis in Campylobacter jejuni. Biochemistry, 47, 2008
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3KPF
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7JGL
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![BU of 7jgl by Molmil](/molmil-images/mine/7jgl) | Crystal Structure of the Zn-bound Human Heavy-chain variant 122H-delta C-star with 2,5-furandihyrdoxamate collected at 100K | Descriptor: | Ferritin heavy chain, N~2~,N~5~-dihydroxyfuran-2,5-dicarboxamide, SODIUM ION, ... | Authors: | Bailey, J.B, Tezcan, F.A. | Deposit date: | 2020-07-19 | Release date: | 2020-10-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Tunable and Cooperative Thermomechanical Properties of Protein-Metal-Organic Frameworks. J.Am.Chem.Soc., 142, 2020
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7JIB
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![BU of 7jib by Molmil](/molmil-images/mine/7jib) | Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1 | Descriptor: | 2'-O-methyltransferase, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, ... | Authors: | Wilamowski, M, Minasov, G, Kim, Y, Sherrell, D.A, Shuvalova, L, Lavens, A, Chard, R, Rosas-Lemus, M, Maltseva, N, Jedrzejczak, R, Michalska, K, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-07-23 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc.Natl.Acad.Sci.USA, 118, 2021
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3BGZ
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![BU of 3bgz by Molmil](/molmil-images/mine/3bgz) | Human Pim-1 kinase in complex with diphenyl indole inhibitor VX3 | Descriptor: | 2,3-diphenyl-1H-indole-7-carboxylic acid, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Jacobs, M.D. | Deposit date: | 2007-11-27 | Release date: | 2007-12-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Docking study yields four novel inhibitors of the protooncogene pim-1 kinase. J.Med.Chem., 51, 2008
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