PDB: 46006 resultsInfo pagesStatus searchChemie searchBIRD

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5LNK	Entire ovine respiratory complex I Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 4'-PHOSPHOPANTETHEINE, ... Authors: Fiedorczuk, K, Letts, J.A, Kaszuba, K, Sazanov, L.A. Deposit date: 2016-08-04 Release date: 2016-11-23 Last modified: 2021-06-02 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Atomic structure of the entire mammalian mitochondrial complex I. Nature, 538, 2016
4YGH	Crystal Structure of R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 2.1 Angstrom resolution - UV irradiated crystal - 2nd cycle Descriptor: Cellular retinoic acid-binding protein 2, RETINAL Authors: Nosrati, M, Geiger, J.H. Deposit date: 2015-02-26 Release date: 2016-03-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
4Y91	Crystal Structure of a Thermotoga maritima Hfq homolog Descriptor: RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), RNA-binding protein Hfq Authors: Randolph, P.S, Patterson, J, Mura, C. Deposit date: 2015-02-16 Release date: 2016-03-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.656 Å) Cite: Crystal Structure of a Thermotoga maritima Hfq homolog To be published
3RKX	Structural characterisation of staphylococcus aureus biotin protein ligase Descriptor: Biotin-[acetyl-CoA-carboxylase] ligase Authors: Wilce, M.C.J. Deposit date: 2011-04-18 Release date: 2012-04-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural characterisation of staphylococcus aureus biotin protein ligase TO BE PUBLISHED
3RIR	Crystal Strucrture of Biotin Protein Ligase from S. aureus Descriptor: BIOTINYL-5-AMP, Biotin-[acetyl-CoA-carboxylase] ligase Authors: Wilce, M.C.J. Deposit date: 2011-04-14 Release date: 2012-04-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Strucrture of Biotin Protein Ligase from S. aureus To be published
3RKW	Structural characterisation of staphylococcus aureus biotin protein ligase Descriptor: BIOTINYL-5-AMP, Biotin-[acetyl-CoA-carboxylase] ligase Authors: Wilce, M.C.J, Pendini, N.R, Yap, M.Y. Deposit date: 2011-04-18 Release date: 2012-04-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural characterisation of staphylococcus aureus biotin protein ligase To be published
3PCU	Crystal structure of human retinoic X receptor alpha ligand-binding domain complexed with LX0278 and SRC1 peptide Descriptor: 2-[(2S)-6-(2-methylbut-3-en-2-yl)-7-oxo-2,3-dihydro-7H-furo[3,2-g]chromen-2-yl]propan-2-yl acetate, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha Authors: Zhang, H, Zhang, Y, Shen, H, Chen, J, Li, C, Chen, L, Hu, L, Jiang, H, Shen, X. Deposit date: 2010-10-22 Release date: 2011-11-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: (+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice. Plos One, 7, 2012
3PEQ	PPARd complexed with a phenoxyacetic acid partial agonist Descriptor: IODIDE ION, Peroxisome proliferator-activated receptor delta, [(4-{butyl[2-methyl-4'-(methylsulfanyl)biphenyl-3-yl]sulfamoyl}naphthalen-1-yl)oxy]acetic acid, ... Authors: Lambert, M.H, Evans, K.A, Shearer, B.G, Wisnoski, D.D, Shi, D, Jin, J, Rivero, R.A, Sparks, S.M, Winegar, D.A, Billin, A.N, Britt, C, Way, J.M, Leesnitzer, L.M, Merrihew, R.V. Deposit date: 2010-10-27 Release date: 2011-10-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Phenoxyacetic acid PPARd partial agonists for the treatment of type 2 diabetes: synthesis, optimization, and in vivo efficacy Bioorg.Med.Chem.Lett., 21, 2011
5A5P	Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one Descriptor: 1,2-ETHANEDIOL, 8-{[2-(dimethylamino)ethyl]amino}-3-methyl-1,2-dihydroquinolin-2-one, ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2, ... Authors: Chung, C, Bamborough, P, Demont, E. Deposit date: 2015-06-20 Release date: 2015-07-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors. J.Med.Chem., 58, 2015
5A81	Crystal structure of human ATAD2 bromodomain in complex with 8-(3R,4R) -3-(cyclohexylmethoxy)piperidin-4-yl-amino-3-methyl-1,2-dihydro-1,7- naphthyridin-2-one Descriptor: (3R,4R)-3-(cyclohexylmethoxy)piperidin-4-yl]amino}-3-methyl-1,2-dihydro-1,7-naphthyridin-2-one, 1,2-ETHANEDIOL, ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2, ... Authors: Chung, C, Bamborough, P, Demont, E. Deposit date: 2015-07-11 Release date: 2015-08-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Structure-Based Optimization of Naphthyridones Into Potent Atad2 Bromodomain Inhibitors. J.Med.Chem., 58, 2015
2H0N	Structure of the fully modified left-handed cyclohexene nucleic acid sequence GTGTACAC Descriptor: 5'-(*(XGL)P*(XTL)P*(XGL)P*(XTL)P*(XAL)P*(XCL)P*(XAL)P*(XCL)-Phosphate)-3', DIHYDROGENPHOSPHATE ION Authors: Robeyns, K, Van Meervelt, L. Deposit date: 2006-05-15 Release date: 2007-04-24 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Structure of the fully modified left-handed cyclohexene nucleic acid sequence GTGTACAC. J.Am.Chem.Soc., 130, 2008
3R8D	Activation of the Human Nuclear Xenobiotic Receptor PXR by the Reverse Transcriptase-Targeted Anti-HIV Drug PNU-142721 Descriptor: 6-CHLORO-2-(1-FURO[2,3-C]PYRIDIN-5-YL-ETHYLSULFANYL)-PYRIMIDIN-4-YLAMINE, Nuclear receptor subfamily 1 group I member 2 Authors: Cheng, Y, Redinbo, M.R. Deposit date: 2011-03-23 Release date: 2011-08-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721. Protein Sci., 20, 2011
3VUX	Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II Descriptor: 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ... Authors: Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2012-07-09 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3ULF	The light state structure of the blue-light photoreceptor Aureochrome1 LOV Descriptor: Aureochrome1, FLAVIN MONONUCLEOTIDE, PHOSPHATE ION Authors: Mitra, D, Yang, X, Moffat, K. Deposit date: 2011-11-10 Release date: 2012-04-11 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structures of Aureochrome1 LOV suggest new design strategies for optogenetics. Structure, 20, 2012
3R29	Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 Descriptor: Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha Authors: Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X. Deposit date: 2011-03-14 Release date: 2011-05-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for retinoic x receptor repression on the tetramer. J.Biol.Chem., 286, 2011
3UE6	The dark structure of the blue-light photoreceptor Aureochrome1 LOV Descriptor: Aureochrome1, FLAVIN MONONUCLEOTIDE, PHOSPHATE ION Authors: Mitra, D, Yang, X, Moffat, K. Deposit date: 2011-10-28 Release date: 2012-04-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structures of Aureochrome1 LOV suggest new design strategies for optogenetics. Structure, 20, 2012
3R2A	Crystal structure of RXRalpha ligand-binding domain complexed with corepressor SMRT2 and antagonist rhein Descriptor: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Nuclear receptor corepressor 2, Retinoic acid receptor RXR-alpha Authors: Zhang, H, Chen, L, Chen, J, Jiang, H, Shen, X. Deposit date: 2011-03-14 Release date: 2011-05-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural basis for retinoic x receptor repression on the tetramer. J.Biol.Chem., 286, 2011
3R8A	X-ray crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a compound with dual PPAR gamma agonism and Angiotensin II Type I receptor antagonism activity Descriptor: 2-ethyl-5,7-dimethyl-3-{(1S)-5-[2-(1H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl}-3H-imidazo[4,5-b]pyridine, Peroxisome proliferator-activated receptor gamma Authors: Ohren, J.F. Deposit date: 2011-03-23 Release date: 2012-03-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-gamma. J.Med.Chem., 54, 2011
3OLS	Crystal structure of estrogen receptor beta ligand binding domain Descriptor: ESTRADIOL, Estrogen receptor beta, Nuclear receptor coactivator 1 Authors: Moecklinghoff, S, Rose, R, Carraz, M, Visser, A, Ottmann, C, Brunsveld, L. Deposit date: 2010-08-26 Release date: 2010-11-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem, 11, 2010
3VUY	Crystal structure of A20 ZF7 in complex with linear tetraubiquitin Descriptor: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... Authors: Nishimasu, H, Ishitani, R, Nureki, O. Deposit date: 2012-07-09 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
2GDG	Crystal structure of covalently modified macrophage inhibitory factor Descriptor: Macrophage migration inhibitory factor Authors: Golubkov, P.A, Hackert, M.L. Deposit date: 2006-03-16 Release date: 2006-07-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Inactivation of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor by 2-oxo-4-phenyl-3-butynoate. Bioorg.Chem., 34, 2006
3OMQ	Fragment-Based Design of novel Estrogen Receptor Ligands Descriptor: 2-[(trifluoromethyl)sulfonyl]-1,2,3,4-tetrahydroisoquinolin-6-ol, Estrogen receptor beta, Nuclear receptor coactivator 1 Authors: Moecklinghoff, S, van Otterlo, W.A, Rose, R, Fuchs, S, Dominguez Seoane, M, Waldmann, H, Ottmann, C, Brunsveld, L. Deposit date: 2010-08-27 Release date: 2011-03-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold-Detection Approach. J.Med.Chem., 54, 2011
3FWC	Sac3:Sus1:Cdc31 complex Descriptor: Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1, ... Authors: Stewart, M, Jani, D. Deposit date: 2009-01-17 Release date: 2009-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
4C7Q	Solution structure of the Nt. GR-RBP1 RRM domain Descriptor: RNA-BINDING GLYCINE-RICH PROTEIN Authors: Kahn, F, Boelens, R, Saqlan, S.M.S, van Ingen, H. Deposit date: 2013-09-24 Release date: 2013-10-02 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Structural Basis of Nucleic Acid Binding by Nicotiana Tabacum Glycine-Rich RNA Binding Protein: Implications for its RNA Chaperone Function Nucleic Acids Res., 42, 2014
3IXP	Crystal structure of the ecdysone receptor bound to BYI08346 Descriptor: Ecdysone receptor, Gene regulation protein, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... Authors: Moras, D, Billas, I.M.L, Browning, C. Deposit date: 2009-09-04 Release date: 2010-12-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Adaptability of the ecdysone receptor bound to synthetic ligands To be Published

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