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6E8L
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BU of 6e8l by Molmil
Crystal Structure of Alkyl hydroperoxidase D (AhpD) from Streptococcus pneumoniae (Strain D39/ NCTC 7466)
Descriptor: Alkyl hydroperoxide reductase AhpD
Authors:Meng, Y, Davies, J, North, R, Coombes, D, Horne, C, Hampton, M, Dobson, R.
Deposit date:2018-07-30
Release date:2019-08-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function analyses of alkylhydroperoxidase D fromStreptococcus pneumoniaereveal an unusual three-cysteine active site architecture.
J.Biol.Chem., 295, 2020
4PFX
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The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold
Descriptor: ACETATE ION, Putative glycosyltransferase (GalT1), URIDINE-5'-DIPHOSPHATE
Authors:Zhang, H, Wu, H.
Deposit date:2014-04-30
Release date:2014-07-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.
Nat Commun, 5, 2014
6EN3
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BU of 6en3 by Molmil
Crystal structure of full length EndoS from Streptococcus pyogenes in complex with G2 oligosaccharide.
Descriptor: CALCIUM ION, Endo-beta-N-acetylglucosaminidase F2,Multifunctional-autoprocessing repeats-in-toxin, NICKEL (II) ION, ...
Authors:Trastoy, B, Klontz, E.H, Orwenyo, J, Marina, A, Wang, L.X, Sundberg, E.J, Guerin, M.E.
Deposit date:2017-10-04
Release date:2018-06-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.
Nat Commun, 9, 2018
5F9T
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BU of 5f9t by Molmil
Crystal Structure of Streptococcus pneumoniae NanC, covalent complex with a fluorinated Neu5Ac derivative
Descriptor: (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, GLYCEROL, ...
Authors:Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L.
Deposit date:2015-12-10
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR.
J.Biol.Chem., 290, 2015
1L4Z
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BU of 1l4z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE COMPLEX OF MICROPLASMINOGEN WITH ALPHA DOMAIN OF STREPTOKINASE IN THE PRESENCE CADMIUM IONS
Descriptor: CADMIUM ION, Plasminogen, Streptokinase
Authors:Wakeham, N, Terzyan, S, Zhai, P, Loy, J.A, Tang, J, Zhang, X.C.
Deposit date:2002-03-06
Release date:2002-12-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Effects of deletion of streptokinase residues 48-59 on plasminogen activation.
PROTEIN ENG., 15, 2002
1VQU
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BU of 1vqu by Molmil
Crystal structure of Anthranilate phosphoribosyltransferase 2 (17130499) from Nostoc sp. at 1.85 A resolution
Descriptor: ACETATE ION, Anthranilate phosphoribosyltransferase 2, GLYCEROL
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-01-05
Release date:2005-01-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Anthranilate phosphoribosyltransferase 2 (17130499) from Nostoc sp. at 1.85 A resolution
To be published
7V6K
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BU of 7v6k by Molmil
Crystal structure of Sortase A from Streptococcus pyogenes in complex with ML346
Descriptor: 5-[3-(4-methoxyphenyl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, MAGNESIUM ION, Sortase
Authors:Yang, C.G, Gan, J.
Deposit date:2021-08-20
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella.
Rsc Med Chem, 13, 2022
3TFL
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BU of 3tfl by Molmil
LytR-Cps2a-Psr family protein with bound octaprenyl pyrophosphate lipid
Descriptor: (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, CPS2A, ...
Authors:Kawai, Y, Marles-Wright, J, Cleverley, R.M, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Khai Bui, N, Hoyland, C.N, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J.
Deposit date:2011-08-16
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
6EB7
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BU of 6eb7 by Molmil
YycF homologue (SP1227) Receiver Domain Activated by BeF3
Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MANGANESE (II) ION
Authors:Riboldi-Tunnicliffe, A, Issacs, N.W.
Deposit date:2018-08-05
Release date:2019-11-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:YycF homologue (SP1227) Receiver Domain Activated by BeF3
To Be Published
5FCZ
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BU of 5fcz by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
Descriptor: 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, B-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
3TEL
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BU of 3tel by Molmil
LytR-CPS2A-Psr family protein with bound octaprenyl pyrophosphate lipid and manganese ion
Descriptor: (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, ACETATE ION, ...
Authors:Kawai, Y, Marles-Wright, J, Cleverley, R.M, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Khai Bui, N, Hoyland, C.N, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J.
Deposit date:2011-08-15
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
3TEP
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BU of 3tep by Molmil
LytR-CPS2a-Psr family protein with bound octaprenyl pyrophosphate lipid and magnesium ion
Descriptor: (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, CPS2A, ...
Authors:Kawai, Y, Marles-Wright, J, Cleverley, R.M, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Khai Bui, N, Hoyland, C.N, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J.
Deposit date:2011-08-15
Release date:2011-10-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
6EBR
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BU of 6ebr by Molmil
Activation of RR02 bound to BeF3
Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MANGANESE (II) ION
Authors:Riboldi-Tunnicliffe, A, Panjikar, S.
Deposit date:2018-08-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.816 Å)
Cite:Activation of RR02 bound to BeF3
To Be Published
6BBW
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BU of 6bbw by Molmil
Structure of the major pilin protein (T3.2) from Streptococcus pyogenes serotype GAS13637
Descriptor: CALCIUM ION, Major pilin backbone protein T-antigen, T3.2.
Authors:Young, P.G, Baker, E.N, Moreland, N.J.
Deposit date:2017-10-19
Release date:2018-10-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
2RJT
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BU of 2rjt by Molmil
Crystal Structure Analysis of a Surface Entropy Reduction Mutant of S. pneumoniae FabF
Descriptor: Beta-ketoacyl-ACP synthase II
Authors:Soisson, S.M, Parthasarathy, G, Becker, J.
Deposit date:2007-10-15
Release date:2008-01-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Surface-entropy reduction approaches to manipulate crystal forms of beta-ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae.
Acta Crystallogr.,Sect.D, 64, 2008
3V7F
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BU of 3v7f by Molmil
Crystal Structure of Streptococcus pyogenes Csn2
Descriptor: CALCIUM ION, Putative uncharacterized protein
Authors:Bae, E, Jung, D.K, Koo, Y.
Deposit date:2011-12-21
Release date:2012-06-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of Streptococcus pyogenes Csn2 reveals calcium-dependent conformational changes in its tertiary and quaternary structure
Plos One, 7, 2012
5FOO
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BU of 5foo by Molmil
6-phospho-beta-glucosidase
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-PHOSPHO-BETA-D GLYCOSIDASE, ...
Authors:Jin, Y, Kwan, D.H, Withers, S.G, Davies, G.J.
Deposit date:2015-11-24
Release date:2016-02-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Chemoenzymatic Synthesis of 6-Phospho-Cyclophellitol as a Novel Probe of 6-Phospho-Beta-Glucosidases.
FEBS Lett., 590, 2016
5FD0
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BU of 5fd0 by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with NAGlucal
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-N-acetylhexosaminidase, GLYCEROL, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
5FGU
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BU of 5fgu by Molmil
Structure of Sda1 nuclease apoprotein as an EGFP fixed-arm fusion
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Green fluorescent protein,Extracellular streptodornase D, ...
Authors:Moon, A.F, Krahn, J.M, Xun, L, Cuneo, M.J, Pedersen, L.C.
Deposit date:2015-12-21
Release date:2016-03-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.896 Å)
Cite:Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.
Nucleic Acids Res., 44, 2016
1A53
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BU of 1a53 by Molmil
COMPLEX OF INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS WITH INDOLE-3-GLYCEROLPHOSPHATE AT 2.0 A RESOLUTION
Descriptor: INDOLE-3-GLYCEROL PHOSPHATE, INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE
Authors:Hennig, M, Darimont, B, Kirschner, K, Jansonius, J.N.
Deposit date:1998-02-19
Release date:1999-03-23
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product.
J.Mol.Biol., 319, 2002
1LBL
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BU of 1lbl by Molmil
Crystal structure of indole-3-glycerol phosphate synthase (IGPS) in complex with 1-(o-carboxyphenylamino)-1-deoxyribulose 5'-phosphate (CdRP)
Descriptor: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, indole-3-glycerol phosphate synthase
Authors:Hennig, M, Darimont, B.D, Kirschner, K, Jansonius, J.N.
Deposit date:2002-04-04
Release date:2002-09-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The catalytic mechanism of indole-3-glycerol phosphate synthase: Crystal structures of complexes of the enzyme from Sulfolobus solfataricus with the substrate analogue, substrate, and product
J.Mol.Biol., 319, 2002
1L0X
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BU of 1l0x by Molmil
TCR beta chain complexed with streptococcal superantigen SpeA
Descriptor: 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL
Authors:Li, H, Sundberg, E.J, Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1L4D
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BU of 1l4d by Molmil
CRYSTAL STRUCTURE OF MICROPLASMINOGEN-STREPTOKINASE ALPHA DOMAIN COMPLEX
Descriptor: PLASMINOGEN, STREPTOKINASE, SULFATE ION
Authors:Wakeham, N, Terzyan, S, Zhai, P, Loy, J.A, Tang, J, Zhang, X.C.
Deposit date:2002-03-04
Release date:2002-12-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effects of deletion of streptokinase residues 48-59 on plasminogen activation
PROTEIN ENG., 15, 2002
6EWJ
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BU of 6ewj by Molmil
Putative sugar aminotransferase Spr1654 from Streptococcus pneumoniae, apo-form
Descriptor: Putative capsular polysaccharide biosynthesis protein
Authors:Achour, A, Sun, R, Sandalova, T, Han, X.
Deposit date:2017-11-04
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis inStreptococcus pneumoniae.
Open Biol, 8, 2018
8F70
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BU of 8f70 by Molmil
Identification of an Immunodominant region on a Group A Streptococcus T-antigen Reveals Temperature-Dependent Motion in Pili
Descriptor: CALCIUM ION, T18.1 Major pilin backbone protein T-antigen,Major pilin backbone protein T-antigen
Authors:Young, P.G, Moreland, N.J.
Deposit date:2022-11-17
Release date:2023-03-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili.
Virulence, 14, 2023

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