6F41
| RNA Polymerase III initially transcribing complex | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | Authors: | Vorlaender, M.K, Khatter, H, Wetzel, R, Hagen, W.J.H, Mueller, C.W. | Deposit date: | 2017-11-29 | Release date: | 2018-01-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular mechanism of promoter opening by RNA polymerase III. Nature, 553, 2018
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6KF4
| Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | Authors: | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | Deposit date: | 2019-07-06 | Release date: | 2020-07-01 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase. Nat Commun, 11, 2020
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4XHI
| Crystal structure of native Thosea asigna virus RNA-dependent RNA polymerase (RdRP) at 2.15 Angstrom resolution | Descriptor: | GLYCEROL, RNA-dependent RNA polymerase, SULFATE ION | Authors: | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | Deposit date: | 2015-01-05 | Release date: | 2015-11-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
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1I5L
| CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM1) FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH SHORT POLY-U RNA | Descriptor: | 5'-R(*UP*UP*U)-3', PUTATIVE SNRNP SM-LIKE PROTEIN AF-SM1, URIDINE | Authors: | Toro, I, Thore, S, Mayer, C, Basquin, J, Seraphin, B, Suck, D. | Deposit date: | 2001-02-28 | Release date: | 2001-08-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex. EMBO J., 20, 2001
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3VAK
| Structure of U2AF65 variant with BrU5 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAF
| Structure of U2AF65 variant with BrU3 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*(BRU)P*UP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAM
| Structure of U2AF65 variant with BrU5C2 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAJ
| Structure of U2AF65 variant with BrU5C6 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*CP*U)-3'), GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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8KAG
| Crystal structure of SpyCas9 in complex with sgRNA and target RNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER) | Authors: | Chen, Y, Chen, J, Liu, L. | Deposit date: | 2023-08-03 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (3.88 Å) | Cite: | Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 2024
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3VAI
| Structure of U2AF65 variant with BrU3C5 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Frato, K.H, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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7SWF
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3VAG
| Structure of U2AF65 variant with BrU3C2 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAH
| Structure of U2AF65 variant with BrU3C4 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(P*UP*UP*(BRU)P*CP*UP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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4XHA
| Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with Lu3+ | Descriptor: | GLYCEROL, LUTETIUM (III) ION, RNA-dependent RNA polymerase, ... | Authors: | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | Deposit date: | 2015-01-05 | Release date: | 2015-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
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1XMQ
| Crystal Structure of t6A37-ASLLysUUU AAA-mRNA Bound to the Decoding Center | Descriptor: | 16s ribosomal RNA, 30S Ribosomal Protein S10, 30S Ribosomal Protein S11, ... | Authors: | Murphy, F.V, Ramakrishnan, V, Malkiewicz, A, Agris, P.F. | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The role of modifications in codon discrimination by tRNA(Lys)(UUU). Nat.Struct.Mol.Biol., 11, 2004
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8HIP
| dsRNA transporter | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Systemic RNA interference defective protein 1, ZINC ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-21 | Release date: | 2023-11-29 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural insights into double-stranded RNA recognition and transport by SID-1. Nat.Struct.Mol.Biol., 31, 2024
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2BX9
| Crystal structure of B.subtilis Anti-TRAP protein, an antagonist of TRAP-RNA interactions | Descriptor: | TRYPTOPHAN RNA-BINDING ATTENUATOR PROTEIN-INHIBITORY PROTEIN, ZINC ION | Authors: | Shevtsov, M.B, Chen, Y, Gollnick, P, Antson, A.A. | Deposit date: | 2005-07-26 | Release date: | 2005-11-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Bacillus Subtilis Anti-Trap Protein, an Antagonist of Trap/RNA Interaction. Proc.Natl.Acad.Sci.USA, 102, 2005
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6TZ1
| In situ structure of BmCPV RNA-dependent RNA polymerase at early-elongation state | Descriptor: | Non-template RNA (5'-D(*(GTA))-R(P*GP*UP*A)-3'), RNA-dependent RNA Polymerase, Template RNA (5'-R(P*AP*GP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-09 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6KOP
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.303 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6TZ2
| In situ structure of BmCPV RNA-dependent RNA polymerase at elongation state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-template RNA (36-MER), ... | Authors: | Cui, Y.X, Zhang, Y.N, Sun, J.C, Zhou, Z.H. | Deposit date: | 2019-08-09 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conservative transcription in three steps visualized in a double-stranded RNA virus. Nat.Struct.Mol.Biol., 26, 2019
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6KOO
| Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt | Descriptor: | DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Li, L, Zhang, Y. | Deposit date: | 2019-08-12 | Release date: | 2020-03-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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8KAK
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8KAL
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8KAM
| Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ... | Authors: | Chen, Y, Chen, J, Liu, L. | Deposit date: | 2023-08-03 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (3.91 Å) | Cite: | Trans-nuclease activity of Cas9 activated by DNA or RNA target binding. Nat.Biotechnol., 2024
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8HCC
| Crystal structure of mTREX1-RNA product complex (AMP) | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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