1IEB
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![BU of 1ieb by Molmil](/molmil-images/mine/1ieb) | HISTOCOMPATIBILITY ANTIGEN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK, SULFATE ION | Authors: | Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J. | Deposit date: | 1996-04-05 | Release date: | 1997-06-05 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996
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1IM3
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![BU of 1im3 by Molmil](/molmil-images/mine/1im3) | Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax | Descriptor: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, Human T-cell lymphotropic virus type 1 Tax peptide, ... | Authors: | Gewurz, B.E, Gaudet, R, Tortorella, D, Wang, E.W, Ploegh, H.L, Wiley, D.C. | Deposit date: | 2001-05-09 | Release date: | 2001-06-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proc.Natl.Acad.Sci.USA, 98, 2001
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1IM9
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![BU of 1im9 by Molmil](/molmil-images/mine/1im9) | Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1 bound to its MHC ligand HLA-Cw4 | Descriptor: | Beta-2 microglobulin, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, CW-4 CW*0401 ALPHA CHAIN, ... | Authors: | Fan, Q.R, Long, E.O, Wiley, D.C. | Deposit date: | 2001-05-10 | Release date: | 2001-05-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nat.Immunol., 2, 2001
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1IGA
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![BU of 1iga by Molmil](/molmil-images/mine/1iga) | |
1JPG
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![BU of 1jpg by Molmil](/molmil-images/mine/1jpg) | Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db | Descriptor: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | Authors: | Ciatto, C, Tissot, A.C, Tschopp, M, Capitani, G, Pecorari, F, Pluckthun, A, Grutter, M.G. | Deposit date: | 2001-08-02 | Release date: | 2001-10-24 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides. J.Mol.Biol., 312, 2001
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1JL4
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![BU of 1jl4 by Molmil](/molmil-images/mine/1jl4) | CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE | Descriptor: | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ... | Authors: | Wang, J.-H, Meijers, R, Reinherz, E.L. | Deposit date: | 2001-07-15 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule. Proc.Natl.Acad.Sci.USA, 98, 2001
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1JWM
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![BU of 1jwm by Molmil](/molmil-images/mine/1jwm) | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3 | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | Deposit date: | 2001-09-04 | Release date: | 2003-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation Structure, 11, 2003
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1JRH
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![BU of 1jrh by Molmil](/molmil-images/mine/1jrh) | COMPLEX (ANTIBODY/ANTIGEN) | Descriptor: | ANTIBODY A6, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN | Authors: | Winkler, F.K, Sogabe, S. | Deposit date: | 1997-09-23 | Release date: | 1998-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex. J.Mol.Biol., 273, 1997
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1K4D
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![BU of 1k4d by Molmil](/molmil-images/mine/1k4d) | Potassium Channel KcsA-Fab complex in low concentration of K+ | Descriptor: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | Authors: | Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R. | Deposit date: | 2001-10-07 | Release date: | 2001-11-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001
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1IAK
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![BU of 1iak by Molmil](/molmil-images/mine/1iak) | |
1I7T
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![BU of 1i7t by Molmil](/molmil-images/mine/1i7t) | CRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1049-5V | Descriptor: | 9 RESIDUE PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Busslep, J, Zhao, R, Loftus, D, Appella, E, Collins, E.J. | Deposit date: | 2001-03-10 | Release date: | 2001-10-24 | Last modified: | 2021-07-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | T cell activity correlates with oligomeric peptide-major histocompatibility complex binding on T cell surface J.Biol.Chem., 276, 2001
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1JWU
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![BU of 1jwu by Molmil](/molmil-images/mine/1jwu) | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2 | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | Deposit date: | 2001-09-05 | Release date: | 2003-07-08 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation Structure, 11, 2003
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1K2D
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![BU of 1k2d by Molmil](/molmil-images/mine/1k2d) | Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A-U alpha chain, ... | Authors: | He, X.L, Radu, C, Ward, E.S, Garcia, K.C. | Deposit date: | 2001-09-26 | Release date: | 2003-03-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural snapshot of aberrant antigen presentation linked to autoimmunity: the
immunodominant epitope of MBP complexed with I-Au IMMUNITY, 17, 2002
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1JE6
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![BU of 1je6 by Molmil](/molmil-images/mine/1je6) | Structure of the MHC Class I Homolog MICB | Descriptor: | MHC class I chain-related protein, SULFATE ION | Authors: | Holmes, M.A, Li, P, Strong, R.K. | Deposit date: | 2001-06-15 | Release date: | 2002-08-07 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D. J.Immunol., 169, 2002
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1KJ2
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![BU of 1kj2 by Molmil](/molmil-images/mine/1kj2) | Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Allogeneic H-2Kb MHC Class I Molecule, Beta-2 microglobulin, ... | Authors: | Reiser, J.-B, Gregoire, C, Darnault, C, Mosser, T, Guimezanes, A, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Mazza, G, Malissen, B, Housset, D. | Deposit date: | 2001-12-04 | Release date: | 2002-03-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex. Immunity, 16, 2002
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1KJV
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![BU of 1kjv by Molmil](/molmil-images/mine/1kjv) | TAP-B-associated rat MHC class I molecule | Descriptor: | Mature alpha chain of major histocompatibility complex class I antigen (HEAVY CHAIN), SULFATE ION, beta-2-microglobulin, ... | Authors: | Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A. | Deposit date: | 2001-12-05 | Release date: | 2002-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially
with peptide transporter alleles TAP-A and TAP-B. J.Mol.Biol., 324, 2002
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1KT2
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![BU of 1kt2 by Molmil](/molmil-images/mine/1kt2) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ... | Authors: | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | Deposit date: | 2002-01-15 | Release date: | 2002-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
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1KTL
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![BU of 1ktl by Molmil](/molmil-images/mine/1ktl) | The human non-classical major histocompatibility complex molecule HLA-E | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN, ... | Authors: | Holmes, M.A, Strong, R.K. | Deposit date: | 2002-01-16 | Release date: | 2003-02-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | HLA-E allelic variants: Correlating differential expression, peptide affinities, crystal structures and thermal stabilities J.Biol.Chem., 278, 2003
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1KLG
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![BU of 1klg by Molmil](/molmil-images/mine/1klg) | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | Deposit date: | 2001-12-11 | Release date: | 2002-08-02 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line. J.Mol.Biol., 319, 2002
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1IAO
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![BU of 1iao by Molmil](/molmil-images/mine/1iao) | CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AD | Authors: | Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A. | Deposit date: | 1998-03-13 | Release date: | 1998-11-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity, 8, 1998
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1KTD
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![BU of 1ktd by Molmil](/molmil-images/mine/1ktd) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ... | Authors: | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | Deposit date: | 2002-01-15 | Release date: | 2002-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
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1K8D
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![BU of 1k8d by Molmil](/molmil-images/mine/1k8d) | crystal structure of the non-classical MHC class Ib Qa-2 complexed with a self peptide | Descriptor: | 60S RIBOSOMAL PROTEIN, BETA-2-MICROGLOBULIN, QA-2 antigen | Authors: | He, X, Tabaczewski, P, Ho, J, Stroynowski, I, Garcia, K.C. | Deposit date: | 2001-10-23 | Release date: | 2001-12-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation. Structure, 9, 2001
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1K5N
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![BU of 1k5n by Molmil](/molmil-images/mine/1k5n) | HLA-B*2709 BOUND TO NONA-PEPTIDE M9 | Descriptor: | GLYCEROL, beta-2-microglobulin, light chain, ... | Authors: | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | Deposit date: | 2001-10-11 | Release date: | 2002-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations J.Biol.Chem., 277, 2002
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1K8I
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![BU of 1k8i by Molmil](/molmil-images/mine/1k8i) | CRYSTAL STRUCTURE OF MOUSE H2-DM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain | Authors: | Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J. | Deposit date: | 2001-10-24 | Release date: | 2001-12-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of mouse H2-M. Immunity, 9, 1998
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1KBG
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![BU of 1kbg by Molmil](/molmil-images/mine/1kbg) | MHC Class I H-2KB Presented Glycopeptide RGY8-6H-GAL2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (BETA-2-MICROGLOBULIN), ... | Authors: | Speir, J.A, Abdel-Motal, U.M, Jondal, M, Wilson, I.A. | Deposit date: | 1998-08-28 | Release date: | 1999-02-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL. Immunity, 10, 1999
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