1M4R
 
 | | CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-22 | | Descriptor: | Interleukin-22 | | Authors: | Nagem, R.A.P, Colau, D, Dumoutier, L, Renauld, J.-C, Ogata, C, Polikarpov, I. | | Deposit date: | 2002-07-03 | | Release date: | 2003-07-07 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Recombinant Human Interleukin-22
Structure, 10, 2002
|
|
1M16
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V). | | Descriptor: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | | Authors: | Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M. | | Deposit date: | 2002-06-17 | | Release date: | 2003-08-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
|
|
1TDQ
 | | Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins | | Descriptor: | Aggrecan core protein, CALCIUM ION, Tenascin-R | | Authors: | Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T. | | Deposit date: | 2004-05-24 | | Release date: | 2004-08-31 | | Last modified: | 2021-03-31 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins
Structure, 12, 2004
|
|
1TFK
 | | Ribonuclease from Escherichia coli complexed with its inhibtor protein | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Colicin D, Colicin D immunity protein | | Authors: | Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. | | Deposit date: | 2004-05-27 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Relation between tRNase activity and the structure of colicin D according to X-ray crystallography
Biochem.Biophys.Res.Commun., 322, 2004
|
|
1TIP
 | | THE BISPHOSPHATASE DOMAIN OF THE BIFUNCTIONAL RAT LIVER 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE | | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, PHOSPHOENZYME INTERMEDIATE OF FRU-2,6-BISPHOSPHATASE | | Authors: | Lee, Y.-H, Olson, T.W, Ogata, C.M, Levitt, D.G, Banaszak, L.J, Lange, A.J. | | Deposit date: | 1997-05-28 | | Release date: | 1998-01-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a trapped phosphoenzyme during a catalytic reaction.
Nat.Struct.Biol., 4, 1997
|
|
1SU4
 | | Crystal structure of calcium ATPase with two bound calcium ions | | Descriptor: | CALCIUM ION, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | | Authors: | Toyoshima, C, Nakasako, M, Nomura, H, Ogawa, H. | | Deposit date: | 2004-03-26 | | Release date: | 2004-05-04 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution
Nature, 405, 2000
|
|
1RWF
 | | Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide | | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. | | Deposit date: | 2003-12-16 | | Release date: | 2004-04-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism
J.Mol.Biol., 337, 2004
|
|
1RWG
 | | Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide | | Descriptor: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. | | Deposit date: | 2003-12-16 | | Release date: | 2004-04-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism
J.Mol.Biol., 337, 2004
|
|
1UA4
 | | Crystal Structure of an ADP-dependent Glucokinase from Pyrococcus furiosus | | Descriptor: | ADENOSINE MONOPHOSPHATE, ADP-dependent glucokinase, alpha-D-glucopyranose, ... | | Authors: | Ito, S, Jeong, J.J, Yoshioka, I, Koga, S, Fushinobu, S, Shoun, H, Wakagi, T. | | Deposit date: | 2003-02-27 | | Release date: | 2004-02-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase
J.Mol.Biol., 331, 2003
|
|
1RZF
 | | Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51 | | Descriptor: | Fab E51 heavy chain, Fab E51 light chain, GLYCEROL, ... | | Authors: | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1SH2
 | | Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic) | | Descriptor: | RNA Polymerase | | Authors: | Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. | | Deposit date: | 2004-02-24 | | Release date: | 2004-03-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
|
|
1UF2
 | | The Atomic Structure of Rice dwarf Virus (RDV) | | Descriptor: | Core protein P3, Outer capsid protein P8, Structural protein P7 | | Authors: | Nakagawa, A, Miyazaki, N, Taka, J, Naitow, H, Ogawa, A, Fujimoto, Z, Mizuno, H, Higashi, T, Watanabe, Y, Omura, T, Cheng, R.H, Tsukihara, T. | | Deposit date: | 2003-05-23 | | Release date: | 2003-10-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The atomic structure of rice dwarf virus reveals the self-assembly mechanism of component proteins.
Structure, 11, 2003
|
|
1S3K
 | | Crystal Structure of a Humanized Fab (hu3S193) in Complex with the Lewis Y Tetrasaccharide | | Descriptor: | GLYCEROL, HU3S193 Fab fragment, heavy chain, ... | | Authors: | Ramsland, P.A, Farrugia, W, Bradford, T.M, Hogarth, P.M, Scott, A.M. | | Deposit date: | 2004-01-13 | | Release date: | 2004-07-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural convergence of antibody binding of carbohydrate determinants in lewis y tumor antigens
J.Mol.Biol., 340, 2004
|
|
1RZ8
 | | CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B | | Descriptor: | Fab 17b heavy chain, Fab 17b light chain | | Authors: | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1TFO
 | | Ribonuclease from Escherichia coli complexed with its inhibitor protein | | Descriptor: | Colicin D, Colicin D immunity protein | | Authors: | Yajima, S, Nakanishi, K, Takahashi, K, Ogawa, T, Kezuka, Y, Hidaka, M, Nonaka, T, Ohsawa, K, Masaki, H. | | Deposit date: | 2004-05-27 | | Release date: | 2005-03-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Relation between tRNase activity and the structure of colicin D according to X-ray crystallography
Biochem.Biophys.Res.Commun., 322, 2004
|
|
3S57
 | | ABH2 cross-linked with undamaged dsDNA-1 containing cofactors | | Descriptor: | 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*AP*TP*CP*AP*CP*TP*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*AP*GP*TP*GP*AP*TP*GP*AP*CP*A)-3', ... | | Authors: | Yi, C, Chen, B, Qi, B, Ramirez, B, Zhang, W, Jia, G, Zhang, L, Li, C.Q, Dinner, A.R, Yang, C.-G, He, C. | | Deposit date: | 2011-05-20 | | Release date: | 2012-06-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Duplex interrogation by a direct DNA repair protein in search of base damage
Nat.Struct.Mol.Biol., 19, 2012
|
|
1SH0
 | | Crystal Structure of Norwalk Virus Polymerase (Triclinic) | | Descriptor: | RNA Polymerase | | Authors: | Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. | | Deposit date: | 2004-02-24 | | Release date: | 2004-03-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
|
|
1UGL
 | | Solution structure of S8-SP11 | | Descriptor: | S-locus pollen protein | | Authors: | Mishima, M, Takayama, S, Sasaki, K, Jee, J.G, Kojima, C, Isogai, A, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-16 | | Release date: | 2003-09-30 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the Male Determinant Factor for Brassica Self-incompatibility
J.Biol.Chem., 278, 2003
|
|
1RZG
 | | Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d | | Descriptor: | ASPARTIC ACID, CYSTEINE, Fab 412d heavy chain, ... | | Authors: | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZ7
 | | CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D | | Descriptor: | Fab 48d heavy chain, Fab 48d light chain, GLYCEROL | | Authors: | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1RZI
 | | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | | Descriptor: | Fab 47e heavy chain, Fab 47e light chain | | Authors: | Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
3R92
 | | Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model. | | Descriptor: | (3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14,15,17,18,19-dodecahydro-13H-10,6-(metheno)pyrrolo[2',1':3,4][1,4,9]triazacyclotetradecino[9,8-a]indole-7-carboxamide, Heat shock protein HSP 90-alpha | | Authors: | Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Golas, J.M, Liu, H, Lucas, J, Boschelli, F, Vogan, E.M, Levin, J.I. | | Deposit date: | 2011-03-24 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5801 Å) | | Cite: | Discovery of a macrocyclic o-aminobenzamide Hsp90 inhibitor with heterocyclic tether that shows extended biomarker activity and in vivo efficacy in a mouse xenograft model.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
3S5A
 | | ABH2 cross-linked to undamaged dsDNA-2 with cofactors | | Descriptor: | 2-OXOGLUTARIC ACID, 5'-D(*CP*TP*GP*TP*CP*TP*CP*AP*CP*TP*GP*TP*CP*G)-3', 5'-D(*TP*CP*GP*AP*CP*AP*GP*TP*GP*AP*GP*AP*CP*A)-3', ... | | Authors: | Yi, C, Chen, B, Qi, B, Ramirez, B, Zhang, W, Jia, G, Zhang, L, Li, C.Q, Dinner, A.R, Yang, C.-G, He, C. | | Deposit date: | 2011-05-21 | | Release date: | 2012-06-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Duplex interrogation by a direct DNA repair protein in search of base damage
Nat.Struct.Mol.Biol., 19, 2012
|
|
3QTF
 | | Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity | | Descriptor: | (6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-8,12-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha | | Authors: | Zapf, C.W, Bloom, J.D, McBean, J.L, Dushin, R.G, Nittoli, T, Ingalls, C, Sutherland, A.G, Sonye, J.P, Eid, C.N, Golas, J, Liu, H, Boschelli, F, Hu, Y, Vogan, E.M, Levin, J.I. | | Deposit date: | 2011-02-22 | | Release date: | 2011-04-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5703 Å) | | Cite: | Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
1V8L
 | | Structure Analysis of the ADP-ribose pyrophosphatase complexed with ADP-ribose | | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribose pyrophosphatase | | Authors: | Yoshiba, S, Ooga, T, Nakagawa, N, Shibata, T, Inoue, Y, Yokoyama, S, Kuramitsu, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-01-10 | | Release date: | 2004-10-19 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal
J.Biol.Chem., 279, 2004
|
|
