PDB: 437 resultsInfo pagesStatus searchChemie searchBIRD

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4F0N	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-04 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.679 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F4T	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-11 Release date: 2013-05-15 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.637 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F8F	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-17 Release date: 2013-05-22 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.676 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F1A	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F1F	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.684 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F1D	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.637 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
1HIT	Receptor binding redefined by a structural switch in a mutant Human Insulin Descriptor: INSULIN Authors: Hua, Q.X, Kochoyan, M, Weiss, M.A. Deposit date: 1992-02-28 Release date: 1994-01-31 Last modified: 2024-06-05 Method: SOLUTION NMR Cite: Receptor binding redefined by a structural switch in a mutant human insulin. Nature, 354, 1991
4F1C	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F1B	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.591 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F1G	Human insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.637 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
1IGL	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR II RELATIONSHIP TO RECEPTOR AND BINDING PROTEIN INTERACTIONS Descriptor: INSULIN-LIKE GROWTH FACTOR II Authors: Torres, A.M, Forbes, B.E, Aplin, S.E, Wallace, J.C, Francis, G.L, Norton, R.S. Deposit date: 1994-12-29 Release date: 1995-02-14 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions. J.Mol.Biol., 248, 1995
1IOH	INSULIN MUTANT A8 HIS,(B1, B10, B16, B27)GLU, DES-B30, NMR, 26 STRUCTURES Descriptor: PROTEIN (INSULIN PRECURSOR) Authors: Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. Deposit date: 1998-08-13 Release date: 1999-01-13 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
1IOG	INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES Descriptor: PROTEIN (INSULIN PRECURSOR) Authors: Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. Deposit date: 1998-08-13 Release date: 1999-01-13 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix. J.Mol.Biol., 284, 1998
4F4V	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-11 Release date: 2013-05-15 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.637 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
4F51	Human Insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. Deposit date: 2012-05-11 Release date: 2013-05-15 Last modified: 2013-12-18 Method: X-RAY DIFFRACTION (1.637 Å) Cite: Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
1IZA	ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN Descriptor: INSULIN Authors: Xiao, B, Dodson, G.G. Deposit date: 1992-10-16 Release date: 1993-10-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin. J.Mol.Biol., 228, 1992
1IZB	ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN Descriptor: INSULIN, ZINC ION Authors: Xiao, B, Dodson, G.G. Deposit date: 1992-10-16 Release date: 1993-10-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2 Å) Cite: Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin. J.Mol.Biol., 228, 1992
3W7Z	1.15A structure of human 2Zn insulin at 293K Descriptor: Insulin, ZINC ION Authors: Hoshikawa, N, Sasaki, K, Sakabe, N, Sakabe, K. Deposit date: 2013-03-11 Release date: 2013-07-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.15 Å) Cite: 1.15A structure of human 2Zn insulin at 293K To be Published
1KMF	NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALLO-ILE, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES Descriptor: Insulin Authors: Xu, B, Hua, Q.X, Nakagawa, S.H, Jia, W, Chu, Y.C, Katsoyannis, P.G, Weiss, M.A. Deposit date: 2001-12-14 Release date: 2002-01-09 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue. J.Mol.Biol., 316, 2002
3ZS2	TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. Deposit date: 2011-06-21 Release date: 2011-08-31 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
3ZQR	NMePheB25 insulin analogue crystal structure Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. Deposit date: 2011-06-10 Release date: 2011-08-24 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
1K3M	NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES Descriptor: INSULIN Authors: Xu, B, Hua, Q.-X, Nakagawa, S.H, Jia, W, Chu, Y.-C, Katsoyannis, P.G, Weiss, M.A. Deposit date: 2001-10-03 Release date: 2001-10-17 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci., 11, 2002
3V19	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health Descriptor: CHLORIDE ION, Insulin, PHENOL, ... Authors: Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. Deposit date: 2011-12-09 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
3ZI3	Crystal structure of the B24His-insulin - human analogue Descriptor: INSULIN, SULFATE ION Authors: Zakova, L, Kletvikova, E, Veverka, V, Lepsik, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. Deposit date: 2013-01-02 Release date: 2013-03-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural Integrity of the B24 Site in Human Insulin is Important for Hormone Functionality J.Biol.Chem., 288, 2013
3ZU1	Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... Authors: Schluckebier, G, Whittingham, J. Deposit date: 2011-07-13 Release date: 2011-08-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin To be Published

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