1RUW
 
 | | Crystal structure of the SH3 domain from S. cerevisiae Myo3 | | Descriptor: | IMIDAZOLE, Myosin-3 isoform | | Authors: | Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M. | | Deposit date: | 2003-12-12 | | Release date: | 2005-03-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the SH3 domain from S. cerevisiae Myo3
To be Published
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1RLQ
 | | TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS | | Descriptor: | C-SRC TYROSINE KINASE SH3 DOMAIN, PROLINE-RICH LIGAND RLP2 (RALPPLPRY) | | Authors: | Feng, S, Chen, J.K, Yu, H, Simon, J.A, Schreiber, S.L. | | Deposit date: | 1994-10-10 | | Release date: | 1995-02-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions.
Science, 266, 1994
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4HVW
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4HVV
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1TG0
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4LE9
 | | Crystal structure of a chimeric c-Src-SH3 domain | | Descriptor: | Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL | | Authors: | Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M. | | Deposit date: | 2013-06-25 | | Release date: | 2014-05-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.344 Å) | | Cite: | 3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops.
J.Struct.Biol., 186, 2014
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1SSH
 | | Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein in complex with a peptide | | Descriptor: | 12-mer peptide from Cytoskeleton assembly control protein SLA1, Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region | | Authors: | Kursula, P, Kursula, I, Lehmann, F, Song, Y.-H, Wilmanns, M. | | Deposit date: | 2004-03-24 | | Release date: | 2005-04-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Yeast SH3 domain structural genomics
To be Published
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4LN2
 | | The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin | | Descriptor: | Sorbin and SH3 domain-containing protein 1, proline rich peptide | | Authors: | Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q. | | Deposit date: | 2013-07-11 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
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1GCQ
 | | CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE | | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | Deposit date: | 2000-08-08 | | Release date: | 2001-08-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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1GFD
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1G2B
 | | ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 | | Descriptor: | SPECTRIN ALPHA CHAIN, SULFATE ION | | Authors: | Berisio, R, Viguera, A.R, Serrano, L, Wilmanns, M. | | Deposit date: | 2000-10-18 | | Release date: | 2000-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Atomic resolution structure of a mutant of the spectrin SH3 domain.
Acta Crystallogr.,Sect.D, 57, 2001
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1HD3
 | | A-SPECTRIN SH3 DOMAIN F52Y MUTANT | | Descriptor: | GLYCEROL, SPECTRIN ALPHA CHAIN, SULFATE ION | | Authors: | Vega, M.C, Viguera, A.R, Serrano, L. | | Deposit date: | 2000-11-06 | | Release date: | 2001-11-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Unspecific Hydrophobic Stabilization of Folding Transition States
Proc.Natl.Acad.Sci.USA, 99, 2002
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1H3H
 | | Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain | | Descriptor: | GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 | | Authors: | Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S. | | Deposit date: | 2002-09-03 | | Release date: | 2003-03-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition
Mol.Cell, 11, 2003
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1H8K
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1H92
 | | SH3 domain of human Lck tyrosine kinase | | Descriptor: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | | Authors: | Schweimer, K, Hoffmann, S, Friedrich, U, Biesinger, B, Roesch, P, Sticht, H. | | Deposit date: | 2001-02-22 | | Release date: | 2001-10-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Investigation of the Binding of a Herpesviral Protein to the SH3 Domain of Tyrosine Kinase Lck
Biochemistry, 41, 2002
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1GCP
 | | CRYSTAL STRUCTURE OF VAV SH3 DOMAIN | | Descriptor: | VAV PROTO-ONCOGENE | | Authors: | Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. | | Deposit date: | 2000-08-08 | | Release date: | 2001-08-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
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1GFC
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1GBQ
 | | SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | GRB2, SOS-1 | | Authors: | Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. | | Deposit date: | 1996-12-23 | | Release date: | 1997-09-04 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997
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1IO6
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1GL5
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1FYN
 | | PHOSPHOTRANSFERASE | | Descriptor: | 3BP-2, PHOSPHOTRANSFERASE FYN | | Authors: | Musacchio, A, Saraste, M, Wilmanns, M. | | Deposit date: | 1995-05-17 | | Release date: | 1996-11-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
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1JEG
 | | Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | | Deposit date: | 2001-06-17 | | Release date: | 2001-10-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand.
Nat.Struct.Biol., 8, 2001
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1HSQ
 | | SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA | | Descriptor: | PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN) | | Authors: | Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F. | | Deposit date: | 1994-06-13 | | Release date: | 1994-08-31 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
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1I07
 | | EPS8 SH3 DOMAIN INTERTWINED DIMER | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | Authors: | Kishan, K.V.R, Newcomer, M.E. | | Deposit date: | 2001-01-29 | | Release date: | 2001-05-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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1I0C
 | | EPS8 SH3 CLOSED MONOMER | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 | | Authors: | Kishan, K.V.R, Newcomer, M.E. | | Deposit date: | 2001-01-29 | | Release date: | 2001-05-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Effect of pH and salt bridges on structural assembly: molecular structures of the monomer and intertwined dimer of the Eps8 SH3 domain.
Protein Sci., 10, 2001
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