7DUG
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7DUJ
| Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1,3''Bz bound | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 30S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | Authors: | DeMirci, H, Destan, E. | Deposit date: | 2021-01-09 | Release date: | 2022-01-12 | Method: | X-RAY DIFFRACTION (3.75 Å) | Cite: | Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with mRNA and cognate transfer RNA anticodon stem-loop and sisomicin derivative N1,3''Bz bound to be published
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7DUH
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4V8O
| Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Jin, H, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2011-07-26 | Release date: | 2014-07-09 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal Structure of the Hybrid State of Ribosome in Complex with the Guanosine Triphosphatase Release Factor 3. Proc.Natl.Acad.Sci.USA, 108, 2011
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2F4V
| 30S ribosome + designer antibiotic | Descriptor: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ... | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | Deposit date: | 2005-11-24 | Release date: | 2006-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site Chem.Biol., 13, 2006
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5OT7
| Elongation factor G-ribosome complex captures in the absence of inhibitors. | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Mace, K, Giudice, E, Chat, S, Gillet, R. | Deposit date: | 2017-08-21 | Release date: | 2018-02-14 | Last modified: | 2018-04-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors. Nucleic Acids Res., 46, 2018
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1N34
| Structure of the Thermus thermophilus 30S ribosomal subunit in the presence of codon and crystallographically disordered near-cognate transfer rna anticodon stem-loop mismatched at the first codon position | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V. | Deposit date: | 2002-10-25 | Release date: | 2002-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form Cell(Cambridge,Mass.), 111, 2002
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5IMQ
| Structure of ribosome bound to cofactor at 3.8 angstrom resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | Deposit date: | 2016-03-06 | Release date: | 2016-05-18 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome J.Biol.Chem., 291, 2016
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4OX9
| Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit | Descriptor: | 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ... | Authors: | Dunkle, J.A, Conn, G.L, Dunham, C.M. | Deposit date: | 2014-02-04 | Release date: | 2014-04-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.8035 Å) | Cite: | Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc.Natl.Acad.Sci.USA, 111, 2014
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4V4J
| Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome. | Descriptor: | 16S RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ... | Authors: | Korostelev, A, Trakhanov, S, Asahara, H, Laurberg, M, Noller, H.F. | Deposit date: | 2007-07-18 | Release date: | 2014-07-09 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.83 Å) | Cite: | Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4DV1
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G, bound with streptomycin | Descriptor: | 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... | Authors: | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Method: | X-RAY DIFFRACTION (3.849 Å) | Cite: | A structural basis for streptomycin resistance To be Published
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4JI5
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | Authors: | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-03-05 | Release date: | 2013-11-06 | Last modified: | 2013-12-04 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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4DV0
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G | Descriptor: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | Authors: | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2012-02-22 | Release date: | 2013-02-27 | Method: | X-RAY DIFFRACTION (3.853 Å) | Cite: | A structural basis for streptomycin resistance To be Published
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4V8J
| Crystal structure of the bacterial ribosome ram mutation G347U. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Fagan, C.E, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | Deposit date: | 2011-12-20 | Release date: | 2014-07-09 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state. Proc.Natl.Acad.Sci.USA, 110, 2013
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5VPP
| The 70S P-site tRNA SufA6 complex | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | Deposit date: | 2017-05-05 | Release date: | 2018-09-26 | Last modified: | 2018-11-07 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4LEL
| Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCG-G on the Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | Deposit date: | 2013-06-25 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.90000033 Å) | Cite: | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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4L71
| Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | Deposit date: | 2013-06-13 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.900001 Å) | Cite: | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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4LFZ
| Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of Paromomycin | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | Deposit date: | 2013-06-27 | Release date: | 2014-08-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.92000055 Å) | Cite: | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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4DR4
| Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2012-02-16 | Release date: | 2012-11-14 | Last modified: | 2013-01-30 | Method: | X-RAY DIFFRACTION (3.969 Å) | Cite: | A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
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6O3M
| Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-02-26 | Release date: | 2020-10-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.97 Å) | Cite: | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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5LMU
| Structure of bacterial 30S-IF3-mRNA-tRNA translation pre-initiation complex, closed form (state-4) | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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6GZZ
| T. thermophilus hibernating 100S ribosome (amc) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Flygaard, R.K, Jenner, L.B. | Deposit date: | 2018-07-05 | Release date: | 2018-10-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.13 Å) | Cite: | Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism. Nat Commun, 9, 2018
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6OSI
| Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (near cognate) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | Deposit date: | 2019-05-01 | Release date: | 2020-10-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (4.14 Å) | Cite: | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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5LMT
| Structure of bacterial 30S-IF1-IF3-mRNA-tRNA translation pre-initiation complex(state-3) | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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5LMQ
| Structure of bacterial 30S-IF1-IF3-mRNA-tRNA translation pre-initiation complex, open form (state-2A) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. | Deposit date: | 2016-08-01 | Release date: | 2016-10-05 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
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