4RQM
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![BU of 4rqm by Molmil](/molmil-images/mine/4rqm) | Crystal structure of the SeMET BICC1 SAM Domain R924E mutant | Descriptor: | Protein bicaudal C homolog 1, ZINC ION | Authors: | Leettola, C.N, Cascio, D, Bowie, J.U. | Deposit date: | 2014-11-03 | Release date: | 2016-01-27 | Last modified: | 2019-10-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6. Structure, 26, 2018
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3KKA
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![BU of 3kka by Molmil](/molmil-images/mine/3kka) | Co-crystal structure of the sam domains of EPHA1 AND EPHA2 | Descriptor: | CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 1, EPHRIN TYPE-A RECEPTOR 2 | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-05 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Co-Crystal Structure of the SAM Domains of Human Ephrin Type-A Receptor 1 and Human Ephrin Type-A Receptor 2 To be Published
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4NL9
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![BU of 4nl9 by Molmil](/molmil-images/mine/4nl9) | |
1UCV
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![BU of 1ucv by Molmil](/molmil-images/mine/1ucv) | Sterile alpha motif (SAM) domain of ephrin type-A receptor 8 | Descriptor: | EPHRIN TYPE-A RECEPTOR 8 | Authors: | Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-04-23 | Release date: | 2004-05-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR Structure of Sterile alpha motif (SAM) domain of ephrin type-A receptor 8 To be Published
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1B4F
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5NZ9
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![BU of 5nz9 by Molmil](/molmil-images/mine/5nz9) | NMR structure of an EphA2-Sam fragment | Descriptor: | Ephrin type-A receptor 2 | Authors: | Mercurio, F.A, Leone, M. | Deposit date: | 2017-05-12 | Release date: | 2017-12-20 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors. Sci Rep, 7, 2017
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2QKQ
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![BU of 2qkq by Molmil](/molmil-images/mine/2qkq) | Structure of the SAM Domain of Human Ephrin Type-B Receptor 4 | Descriptor: | CHLORIDE ION, Ephrin type-B receptor 4 | Authors: | Walker, J.R, Cuerrier, D, Butler-Cole, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-07-11 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | SAM Domain of Human Ephrin Type-B Receptor 4 (EPHB4) TO BE PUBLISHED
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1F0M
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![BU of 1f0m by Molmil](/molmil-images/mine/1f0m) | MONOMERIC STRUCTURE OF THE HUMAN EPHB2 SAM (STERILE ALPHA MOTIF) DOMAIN | Descriptor: | EPHRIN TYPE-B RECEPTOR 2 | Authors: | Thanos, C.D, Faham, S, Goodwill, K.E, Cascio, D, Phillips, M, Bowie, J.U. | Deposit date: | 2000-05-16 | Release date: | 2000-07-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Monomeric structure of the human EphB2 sterile alpha motif domain. J.Biol.Chem., 274, 1999
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4IS7
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![BU of 4is7 by Molmil](/molmil-images/mine/4is7) | |
8J1I
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![BU of 8j1i by Molmil](/molmil-images/mine/8j1i) | Crystal Structure of EphA8/SASH1 Complex | Descriptor: | Ephrin type-A receptor 8, SAM and SH3 domain-containing protein 1 | Authors: | Liu, W, Li, J, Ding, Y. | Deposit date: | 2023-04-12 | Release date: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of EphA8 and SASH1 complex at 1.60 Angstroms resolution To Be Published
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6LUK
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6LUJ
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![BU of 6luj by Molmil](/molmil-images/mine/6luj) | Crystal structure of the SAMD1 SAM domain | Descriptor: | Atherin, SULFATE ION | Authors: | Cao, Y, Zhou, Y, Wang, Z. | Deposit date: | 2020-01-29 | Release date: | 2021-02-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7, 2021
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2F3N
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3HIL
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![BU of 3hil by Molmil](/molmil-images/mine/3hil) | SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1) | Descriptor: | CHLORIDE ION, Ephrin type-A receptor 1, NITRATE ION | Authors: | Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-05-20 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | SAM Domain of Human Ephrin Type-A Receptor 1 (EphA1). To be Published
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1X40
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![BU of 1x40 by Molmil](/molmil-images/mine/1x40) | Solution structure of the SAM domain of human ARAP2 | Descriptor: | ARAP2 | Authors: | Sasagawa, A, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-12 | Release date: | 2005-11-12 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the SAM domain of human ARAP2 To be Published
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5J8Y
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2F44
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8ATJ
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![BU of 8atj by Molmil](/molmil-images/mine/8atj) | Crystal Structure of Shank2-SAM domain | Descriptor: | CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-08-23 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.117 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
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8B10
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![BU of 8b10 by Molmil](/molmil-images/mine/8b10) | Crystal Structure of Shank2-SAM mutant domain - L1800W | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bento, I, Gracia Alai, M, Kreienkamp, J.-H. | Deposit date: | 2022-09-08 | Release date: | 2022-11-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
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5L1M
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![BU of 5l1m by Molmil](/molmil-images/mine/5l1m) | CASKIN2 SAM domain tandem | Descriptor: | Caskin-2 | Authors: | Donaldson, L.W, Kwan, J.J, Saridakis, V. | Deposit date: | 2016-07-29 | Release date: | 2016-08-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.751 Å) | Cite: | A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Commun. Signal, 14, 2016
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3SEN
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![BU of 3sen by Molmil](/molmil-images/mine/3sen) | Structure of Caskin1 Tandem SAMs | Descriptor: | Caskin-1, POTASSIUM ION | Authors: | Stafford, R.L, Bowie, J.U. | Deposit date: | 2011-06-10 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK. Structure, 19, 2011
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1V85
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![BU of 1v85 by Molmil](/molmil-images/mine/1v85) | Sterile alpha motif (SAM) domain of mouse bifunctional apoptosis regulator | Descriptor: | similar to ring finger protein 36 | Authors: | Goroncy, A, Kigawa, T, Koshiba, S, Hayashi, F, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-12-29 | Release date: | 2005-01-25 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Sterile alpha motif (SAM) domain of mouse bifunctional apoptosis regulator To be Published
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3SEI
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![BU of 3sei by Molmil](/molmil-images/mine/3sei) | Crystal Structure of Caskin1 Tandem SAMs | Descriptor: | CHLORIDE ION, Caskin-1, SULFATE ION | Authors: | Stafford, R.L, Bowie, J.U. | Deposit date: | 2011-06-10 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK. Structure, 19, 2011
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6F7M
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![BU of 6f7m by Molmil](/molmil-images/mine/6f7m) | NMR structure of EphA2-Sam stapled peptides (S13ST) | Descriptor: | Ephrin type-A receptor 2 | Authors: | Mercurio, F.A, Leone, M. | Deposit date: | 2017-12-11 | Release date: | 2018-08-01 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2. Bioorg. Chem., 80, 2018
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6FXF
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![BU of 6fxf by Molmil](/molmil-images/mine/6fxf) | |