6SAB
 
 | | M-BUTX-Ptr1a (Parabuthus transvaalicus) | | Descriptor: | M-BUTX-Ptr1a | | Authors: | Meudal, H, Landon, C, Delmas, A.F. | | Deposit date: | 2019-07-16 | | Release date: | 2020-07-22 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
J.Med.Chem., 63, 2020
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2K4U
 | | Solution structure of the SCORPION TOXIN ADWX-1 | | Descriptor: | Potassium channel toxin alpha-KTx 3.6 | | Authors: | Yin, S.J, Jiang, L, Yi, H, Han, S, Yang, D.W, Liu, M.L, Liu, H, Cao, Z.J, Wu, Y.L, Li, W.X. | | Deposit date: | 2008-06-18 | | Release date: | 2008-12-09 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels
J.Proteome Res., 7, 2008
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6GGZ
 | | NMR structure of the scorpion toxin AmmTx3 | | Descriptor: | Potassium channel toxin alpha-KTx 15.3 | | Authors: | Landon, C, Meudal, H. | | Deposit date: | 2018-05-04 | | Release date: | 2019-01-30 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3.
Bioorg. Med. Chem., 27, 2019
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6VNZ
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6MZT
 | | Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi | | Descriptor: | Potassium channel toxin alpha-KTx 6.21 | | Authors: | Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F. | | Deposit date: | 2018-11-05 | | Release date: | 2020-03-11 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem. Pharmacol., 174, 2020
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3E8Y
 | | Xray structure of scorpion toxin BmBKTx1 | | Descriptor: | CHLORIDE ION, Potassium channel toxin alpha-KTx 19.1, SULFATE ION | | Authors: | Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H. | | Deposit date: | 2008-08-20 | | Release date: | 2009-02-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.
J.Am.Chem.Soc., 131, 2009
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3ODV
 | | X-ray structure of kaliotoxin by racemic protein crystallography | | Descriptor: | CITRIC ACID, Potassium channel toxin alpha-KTx 3.1, trifluoroacetic acid | | Authors: | Pentelute, B.L, Mandal, K, Gates, Z.P, Sawaya, M.R, Yeates, T.O, Kent, S.B.H. | | Deposit date: | 2010-08-11 | | Release date: | 2010-10-20 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
Chem.Commun.(Camb.), 46, 2010
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1HP2
 | | SOLUTION STRUCTURE OF A TOXIN FROM THE SCORPION TITYUS SERRULATUS (TSTX-K ALPHA) DETERMINED BY NMR. | | Descriptor: | TITYUSTOXIN K ALPHA | | Authors: | Ellis, K.C, Tenenholz, T.C, Gilly, W.F, Blaustein, M.P, Weber, D.J. | | Deposit date: | 2000-12-12 | | Release date: | 2001-06-13 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A).
Biochemistry, 40, 2001
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1HLY
 | | SOLUTION STRUCTURE OF HONGOTOXIN 1 | | Descriptor: | HONGOTOXIN 1 | | Authors: | Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G. | | Deposit date: | 2000-12-04 | | Release date: | 2003-09-30 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The
first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
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2RTZ
 | | Solution structure of MarkTX-7 | | Descriptor: | Potassium channel blocker MarkTX-7 | | Authors: | Umetsu, Y, Ohki, S. | | Deposit date: | 2013-10-17 | | Release date: | 2014-10-22 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of MarkTX-7
To be Published
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2UVS
 | | High Resolution Solid-state NMR structure of Kaliotoxin | | Descriptor: | POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1 | | Authors: | Korukottu, J, Lange, A, Vijayan, V, Schneider, R, Pongs, O, Becker, S, Baldus, M, Zweckstetter, M. | | Deposit date: | 2007-03-14 | | Release date: | 2008-05-27 | | Last modified: | 2024-11-06 | | Method: | SOLID-STATE NMR | | Cite: | Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin
To be Published
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2PTA
 | | PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES | | Descriptor: | PANDINUS TOXIN K-ALPHA | | Authors: | Tenenholz, T.C, Rogowski, R.S, Collins, J.H, Blaustein, M.P, Weber, D.J. | | Deposit date: | 1996-11-26 | | Release date: | 1997-12-10 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.
Biochemistry, 36, 1997
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1J5J
 | | Solution structure of HERG-specific scorpion toxin BeKm-1 | | Descriptor: | BeKm-1 toxin | | Authors: | Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. | | Deposit date: | 2002-04-16 | | Release date: | 2002-11-20 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
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1KTX
 | | KALIOTOXIN (1-37) SHOWS STRUCTURAL DIFFERENCES WITH RELATED POTASSIUM CHANNEL BLOCKERS | | Descriptor: | KALIOTOXIN | | Authors: | Fernandez, I, Romi, R, Szendefi, S, Martin-Eauclaire, M.-F, Rochat, H, Van Rietschtoten, J, Pons, M, Giralt, E. | | Deposit date: | 1994-06-02 | | Release date: | 1995-01-26 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Kaliotoxin (1-37) shows structural differences with related potassium channel blockers.
Biochemistry, 33, 1994
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1LIR
 | | LQ2 FROM LEIURUS QUINQUESTRIATUS, NMR, 22 STRUCTURES | | Descriptor: | LQ2 | | Authors: | Renisio, J.G, Lu, Z, Blanc, E, Jin, W, Lewis, J.H, Bornet, O, Darbon, H. | | Deposit date: | 1998-04-02 | | Release date: | 1998-06-17 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Solution structure of potassium channel-inhibiting scorpion toxin Lq2.
Proteins, 34, 1999
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1LGL
 | | Solution structure of HERG-specific scorpion toxin BeKm-1 | | Descriptor: | BeKm-1 toxin | | Authors: | Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. | | Deposit date: | 2002-04-16 | | Release date: | 2002-11-20 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002
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1M2S
 | | Solution Structure of A New Potassium Channels Blocker from the Venom of Chinese Scorpion Buthus martensi Karsch | | Descriptor: | Toxin BmTX3 | | Authors: | Wang, Y, Li, M, Zhang, N, Wu, G, Hu, G, Wu, H. | | Deposit date: | 2002-06-25 | | Release date: | 2004-04-06 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | The solution structure of BmTx3B, a member of the scorpion toxin subfamily alpha-KTx 16
Proteins, 58, 2005
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1MTX
 | | DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF MARGATOXIN BY 1H, 13C, 15N TRIPLE-RESONANCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY | | Descriptor: | MARGATOXIN | | Authors: | Johnson, B.A, Stevens, S.P, Williamson, J.M. | | Deposit date: | 1994-12-27 | | Release date: | 1995-11-14 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Determination of the three-dimensional structure of margatoxin by 1H, 13C, 15N triple-resonance nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
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2CRD
 | | ANALYSIS OF SIDE-CHAIN ORGANIZATION ON A REFINED MODEL OF CHARYBDOTOXIN: STRUCTURAL AND FUNCTIONAL IMPLICATIONS | | Descriptor: | CHARYBDOTOXIN | | Authors: | Bontems, F, Roumestand, C, Gilquin, B, Menez, A, Toma, F. | | Deposit date: | 1993-02-17 | | Release date: | 1993-07-15 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications.
Biochemistry, 31, 1992
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1WPD
 | | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins | | Descriptor: | Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3 | | Authors: | Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M. | | Deposit date: | 2004-09-01 | | Release date: | 2004-10-19 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004
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1WZ5
 | | Solution structure of Pi1-3p | | Descriptor: | Potassium channel blocking toxin 1 | | Authors: | Ferrat, G. | | Deposit date: | 2005-02-24 | | Release date: | 2005-04-19 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | The impact of the fourth disulfide bridge in scorpion toxins of the alpha-KTx6 subfamily
Proteins, 61, 2005
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1WT7
 | | Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera | | Descriptor: | BuTX-MTX | | Authors: | M'Barek, S, Chagot, B, Andreotti, N, Visan, V, Mansuelle, P, Grissmer, S, Marrakchi, M, El Ayeb, M, Sampieri, F, Darbon, H, Fajloun, Z, De Waard, M, Sabatier, J.-M. | | Deposit date: | 2004-11-16 | | Release date: | 2004-11-30 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.
Proteins, 60, 2005
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1SXM
 | | SCORPION TOXIN (NOXIUSTOXIN) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL AND LOW AFFINITY FOR CALCIUM DEPENDENT POTASSIUM CHANNEL (NMR AT 20 DEGREES, PH3.5, 39 STRUCTURES) | | Descriptor: | NOXIUSTOXIN | | Authors: | Dauplais, M, Gilquin, B, Possani, L.D, Gurrola-Briones, G, Roumestand, C, Menez, A. | | Deposit date: | 1995-09-07 | | Release date: | 1996-01-29 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry, 34, 1995
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1N8M
 | | Solution structure of Pi4, a four disulfide bridged scorpion toxin active on potassium channels | | Descriptor: | Potassium channel blocking toxin 4 | | Authors: | Guijarro, J.I, M'Barek, S, Olamendi-Portugal, T, Gomez-Lagunas, F, Garnier, D, Rochat, H, Possani, L.D, Sabatier, J.M, Delepierre, M. | | Deposit date: | 2002-11-21 | | Release date: | 2003-09-02 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Protein Sci., 12, 2003
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1WMT
 | | Scorpion toxin (IsTX) from Opisthacanthus madagascariensis | | Descriptor: | IsTX | | Authors: | Yamaji, N, Dai, L, Sugase, K, Andriantsiferana, M, Nakajima, T, Iwashita, T. | | Deposit date: | 2004-07-20 | | Release date: | 2004-10-19 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Solution structure of IsTX: A male scorpion toxin from Opisthacanthus madagascariensis (Ischnuridae)
Eur.J.Biochem., 271, 2004
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