6JQ2
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![BU of 6jq2 by Molmil](/molmil-images/mine/6jq2) | Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | Descriptor: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | Authors: | Bai, P, Yin, L. | Deposit date: | 2019-03-28 | Release date: | 2020-04-01 | Last modified: | 2021-02-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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1MWA
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![BU of 1mwa by Molmil](/molmil-images/mine/1mwa) | 2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2C T CELL RECEPTOR ALPHA CHAIN, ... | Authors: | Luz, J.G, Huang, M.D, Garcia, K.C, Rudolph, M.G, Teyton, L, Wilson, I.A. | Deposit date: | 2002-09-27 | Release date: | 2002-11-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility
complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially
increasing V(beta) Interactions. J.EXP.MED., 195, 2002
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2MHA
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![BU of 2mha by Molmil](/molmil-images/mine/2mha) | CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION | Descriptor: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU | Authors: | Zhang, W, Young, A.C.M, Imarai, M, Nathenson, S.G, Sacchettini, J.C. | Deposit date: | 1993-07-21 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc.Natl.Acad.Sci.USA, 89, 1992
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3P4M
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![BU of 3p4m by Molmil](/molmil-images/mine/3p4m) | Crystal Structure of H2-Kb in complex with the NP205-LCMV epitope YTVKYPNL, an 8-mer peptide from the LCMV | Descriptor: | ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Gras, S, Guillonneau, C, Rossjohn, J. | Deposit date: | 2010-10-06 | Release date: | 2011-10-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of H2-Kb in complex with the NP205-LCMV epitope YTVKYPNL, an 8-mer peptide from the LCMV To be Published
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1FO0
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![BU of 1fo0 by Molmil](/molmil-images/mine/1fo0) | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | Descriptor: | NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ... | Authors: | Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G. | Deposit date: | 2000-08-24 | Release date: | 2000-10-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat.Immunol., 1, 2000
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2VAB
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![BU of 2vab by Molmil](/molmil-images/mine/2vab) | |
3P4N
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![BU of 3p4n by Molmil](/molmil-images/mine/3p4n) | Crystal Structure of H2-Kb in complex with the NP205-PV epitope YTVKFPNM, an 8-mer peptide from PV | Descriptor: | ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Gras, S, Guillonneau, C, Rossjohn, J. | Deposit date: | 2010-10-06 | Release date: | 2011-10-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of H2-Kb in complex with the NP205-PV epitope YTVKFPNM, an 8-mer peptide from PV To be Published
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1VAC
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![BU of 1vac by Molmil](/molmil-images/mine/1vac) | |
1VAD
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![BU of 1vad by Molmil](/molmil-images/mine/1vad) | |
6JQ3
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![BU of 6jq3 by Molmil](/molmil-images/mine/6jq3) | Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide | Descriptor: | Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... | Authors: | Bai, P, Zhou, Q, Wei, P, Yin, L. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2021-02-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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3ROL
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![BU of 3rol by Molmil](/molmil-images/mine/3rol) | Murine class I major histocompatibility complex H-2Kb in complex with post-translationally modified LCMV-derived gp34-41 peptide, comprising a nitrotyrosine at position 3 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Madhurantakam, C, Duru, A.D, Leong, C, Sandalova, T, Webb, J.R, Achour, A. | Deposit date: | 2011-04-26 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition PLoS ONE, 2012
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1RJZ
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![BU of 1rjz by Molmil](/molmil-images/mine/1rjz) | Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpies Simplex Virus Mutant Glycoprotein B Peptide | Descriptor: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | Authors: | Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. | Deposit date: | 2003-11-20 | Release date: | 2004-12-14 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
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1RK0
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![BU of 1rk0 by Molmil](/molmil-images/mine/1rk0) | Mhc Class I H-2Kb Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Glycoprotein B, ... | Authors: | Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. | Deposit date: | 2003-11-20 | Release date: | 2004-12-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
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2FO4
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![BU of 2fo4 by Molmil](/molmil-images/mine/2fo4) | |
4PGD
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![BU of 4pgd by Molmil](/molmil-images/mine/4pgd) | MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAF | Descriptor: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | Authors: | Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J. | Deposit date: | 2014-05-01 | Release date: | 2015-01-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The first step of peptide selection in antigen presentation by MHC class I molecules. Proc.Natl.Acad.Sci.USA, 112, 2015
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1NAM
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![BU of 1nam by Molmil](/molmil-images/mine/1nam) | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BM3.3 T Cell Receptor alpha-Chain, BM3.3 T Cell Receptor beta-Chain, ... | Authors: | Reiser, J.-B, Darnault, C, Gregoire, C, Mosser, T, Mazza, G, Kearnay, A, van der Merwe, P.A, Fontecilla-Camps, J.C, Housset, D, Malissen, B. | Deposit date: | 2002-11-28 | Release date: | 2003-03-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | CDR3 loop flexibility contributes to the degeneracy of TCR recognition Nat.Immunol., 4, 2003
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1KJ2
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![BU of 1kj2 by Molmil](/molmil-images/mine/1kj2) | Murine Alloreactive ScFv TCR-Peptide-MHC Class I Molecule Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Allogeneic H-2Kb MHC Class I Molecule, Beta-2 microglobulin, ... | Authors: | Reiser, J.-B, Gregoire, C, Darnault, C, Mosser, T, Guimezanes, A, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Mazza, G, Malissen, B, Housset, D. | Deposit date: | 2001-12-04 | Release date: | 2002-03-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex. Immunity, 16, 2002
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4PGB
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![BU of 4pgb by Molmil](/molmil-images/mine/4pgb) | MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNWPAL | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | Authors: | Celie, P.H.N, Joosten, R.P, Perrakis, A, Neefjes, J. | Deposit date: | 2014-05-01 | Release date: | 2015-01-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The first step of peptide selection in antigen presentation by MHC class I molecules. Proc.Natl.Acad.Sci.USA, 112, 2015
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1BQH
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![BU of 1bqh by Molmil](/molmil-images/mine/1bqh) | MURINE CD8AA ECTODOMAIN FRAGMENT IN COMPLEX WITH H-2KB/VSV8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (BETA-2-MICROGLOBULIN ), PROTEIN (CD8A OR LYT2 OR LYT-2), ... | Authors: | Wang, J.H, Reinherz, E.L, Kern, P.S, Chang, H.C. | Deposit date: | 1998-08-16 | Release date: | 1998-08-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb. Immunity, 9, 1998
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2ZSW
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![BU of 2zsw by Molmil](/molmil-images/mine/2zsw) | Crystal structure of H-2Kb in complex with the Q600Y variant of JHMV epitope S598 | Descriptor: | 8-mer peptide from spike glycoprotein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Theodossis, A, Dunstone, M.A, Rossjohn, J. | Deposit date: | 2008-09-18 | Release date: | 2008-11-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. Plos Pathog., 4, 2008
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1G6R
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![BU of 1g6r by Molmil](/molmil-images/mine/1g6r) | A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX | Descriptor: | ALPHA T CELL RECEPTOR, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | Authors: | Degano, M, Garcia, K.C, Apostolopoulos, V, Rudolph, M.G, Teyton, L, Wilson, I.A. | Deposit date: | 2000-11-07 | Release date: | 2000-11-15 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity, 12, 2000
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3CVH
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![BU of 3cvh by Molmil](/molmil-images/mine/3cvh) | How TCR-like antibody recognizes MHC-bound peptide | Descriptor: | 25-D1.16 heavy chain, 25-D1.16 light chain, Beta-2-microglobulin, ... | Authors: | Mareeva, T, Martinez-Hackert, E, Sykulev, Y. | Deposit date: | 2008-04-18 | Release date: | 2008-09-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide J.Biol.Chem., 283, 2008
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3RGV
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![BU of 3rgv by Molmil](/molmil-images/mine/3rgv) | A single TCR bound to MHCI and MHC II reveals switchable TCR conformers | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | Authors: | Dai, S, Huseby, E, Scott-Browne, J, Rubtsova, K, Pinilla, C, Crawford, F, Marrack, P, Yin, L, Kappler, J.W. | Deposit date: | 2011-04-09 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers. Immunity, 35, 2011
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2OL3
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![BU of 2ol3 by Molmil](/molmil-images/mine/2ol3) | crystal structure of BM3.3 ScFV TCR in complex with PBM8-H-2KBM8 MHC class I molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALLOGENEIC H-2KBM8 MHC CLASS I MOLECULE, BM3.3 T-CELL RECEPTOR ALPHA-CHAIN, ... | Authors: | Mazza, C, Auphan-Anezin, N, Gregoire, C, Guimezanes, A, Kellenberger, C, Roussel, A, Kearney, A, Van der Merwe, P.A, Schmitt-Verhulst, A.M, Malissen, B. | Deposit date: | 2007-01-18 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? Embo J., 26, 2007
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1P4L
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![BU of 1p4l by Molmil](/molmil-images/mine/1p4l) | Crystal structure of NK receptor Ly49C mutant with its MHC class I ligand H-2Kb | Descriptor: | Beta-2-microglobulin, LY49-C, MHC CLASS I H-2KB HEAVY CHAIN, ... | Authors: | Dam, J, Guan, R, Natarajan, K, Dimasi, N, Mariuzza, R.A. | Deposit date: | 2003-04-23 | Release date: | 2003-11-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nat.Immunol., 4, 2003
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