PDB: 4068 件ウェブページステータス検索Chemie searchBIRD

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8GCH	GAMMA-CHYMOTRYPSIN IS A COMPLEX OF ALPHA-CHYMOTRYPSIN WITH ITS OWN AUTOLYSIS PRODUCTS 分子名称: GAMMA-CHYMOTRYPSIN A, GLY ALA TRP PEPTIDE, SULFATE ION 著者 Harel, M, Sussman, J.L, Silman, I. 登録日 1991-03-27 公開日 1992-04-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Gamma-chymotrypsin is a complex of alpha-chymotrypsin with its own autolysis products. Biochemistry, 30, 1991
1UHB	Crystal structure of porcine alpha trypsin bound with auto catalyticaly produced native peptide at 2.15 A resolution 分子名称: 9-mer peptide from Trypsin, ACETATE ION, CALCIUM ION, ... 著者 Pattabhi, V, Syed Ibrahim, B, Shamaladevi, N. 登録日 2003-06-27 公開日 2004-07-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Trypsin activity reduced by an autocatalytically produced nonapeptide. J.Biomol.Struct.Dyn., 21, 2004
5LGO	Trypsin inhibitors for the treatment of pancreatitis - cpd 15 分子名称: (2~{S},4~{S})-1-[4-(aminomethyl)-3-methoxy-phenyl]carbonyl-4-[4-(2-cyclopropylethoxy)-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidin-7-yl]-~{N}-methyl-pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... 著者 Schiering, N, D'Arcy, A. 登録日 2016-07-07 公開日 2016-08-10 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Trypsin inhibitors for the treatment of pancreatitis. Bioorg.Med.Chem.Lett., 26, 2016
5LH8	Trypsin inhibitors for the treatment of pancreatitis - cpd 8 分子名称: (2~{S},4~{S})-1-[4-(aminomethyl)-3-methoxy-phenyl]carbonyl-4-(4-cyclopropyl-1,2,3-triazol-1-yl)-~{N}-[(1~{S},2~{R})-2-phenylcyclohexyl]pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... 著者 Schiering, N, D'Arcy, A, Skaanderup, P, Simic, O, Brandl, T, Woelcke, J. 登録日 2016-07-08 公開日 2016-08-10 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Trypsin inhibitors for the treatment of pancreatitis. Bioorg.Med.Chem.Lett., 26, 2016
5LH4	Trypsin inhibitors for the treatment of pancreatitis - cpd 1 分子名称: (2~{S},4~{S})-1-[4-(aminomethyl)phenyl]carbonyl-4-(4-cyclopropyl-1,2,3-triazol-1-yl)-~{N}-(2,2-diphenylethyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... 著者 Schiering, N, D'Arcy, A, Skaanderup, P, Simic, O, Brandl, T, Woelcke, J. 登録日 2016-07-08 公開日 2018-01-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Trypsin inhibitors for the treatment of pancreatitis. Bioorg. Med. Chem. Lett., 26, 2016
1PQ8	Trypsin at pH 4 at atomic resolution 分子名称: CITRIC ACID, GLY-GLY-ARG PEPTIDE, LYSINE, ... 著者 Schmidt, A, Jelsch, C, Rypniewski, W, Lamzin, V.S. 登録日 2003-06-18 公開日 2003-11-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS. J.Biol.Chem., 278, 2003
1PQ5	Trypsin at pH 5, 0.85 A 分子名称: ARGININE, SULFATE ION, Trypsin 著者 Schmidt, A, Jelsch, C, Rypniewski, W, Lamzin, V.S. 登録日 2003-06-18 公開日 2003-11-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS. J.Biol.Chem., 278, 2003
1PPZ	Trypsin complexes at atomic and ultra-high resolution 分子名称: SULFATE ION, Trypsin 著者 Schmidt, A, Jelsch, C, Rypniewski, W, Lamzin, V.S. 登録日 2003-06-17 公開日 2003-11-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS. J.Biol.Chem., 278, 2003
1PQA	Trypsin with PMSF at atomic resolution 分子名称: SULFATE ION, Trypsin 著者 Schmidt, A, Jelsch, C, Rypniewski, W, Lamzin, V.S. 登録日 2003-06-18 公開日 2003-11-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS. J.Biol.Chem., 278, 2003
1PQ7	Trypsin at 0.8 A, pH5 / borax 分子名称: ARGININE, SULFATE ION, Trypsin 著者 Schmidt, A, Jelsch, C, Rypniewski, W, Lamzin, V.S. 登録日 2003-06-18 公開日 2003-11-11 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Trypsin Revisited: CRYSTALLOGRAPHY AT (SUB) ATOMIC RESOLUTION AND QUANTUM CHEMISTRY REVEALING DETAILS OF CATALYSIS. J.Biol.Chem., 278, 2003
1KCT	ALPHA1-ANTITRYPSIN 分子名称: ALPHA1-ANTITRYPSIN 著者 Song, H.K, Suh, S.W. 登録日 1996-08-06 公開日 1997-01-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop. FEBS Lett., 377, 1995
2K51	NMR Solution Structure of the Neurotrypsin Kringle Domain 分子名称: Neurotrypsin 著者 Ozhogina, O.A. 登録日 2008-06-23 公開日 2008-12-09 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of the Neurotrypsin Kringle Domain Biochemistry, 47, 2008
2K4R	NMR solution structure of the neurotrypsin kringle domain 分子名称: Neurotrypsin 著者 Ozhogina, O.A. 登録日 2008-06-16 公開日 2008-12-09 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of the Neurotrypsin Kringle Domain Biochemistry, 47, 2008
1QMN	Alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion) 分子名称: ALPHA-1-ANTICHYMOTRYPSIN 著者 Gooptu, B, Hazes, B, Lomas, D.A. 登録日 1999-10-04 公開日 2000-01-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease Proc.Natl.Acad.Sci.USA, 97, 2000
4WWY	human cationic trypsin G193R mutant in complex with bovine pancreatic trypsin inhibitor 分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... 著者 Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S. 登録日 2014-11-12 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. J.Biol.Chem., 290, 2015
4WXV	Human cationic trypsin K97D mutant in complex with bovine pancreatic trypsin inhibitor (BPTI) 分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... 著者 Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S. 登録日 2014-11-14 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates. J.Biol.Chem., 290, 2015
1YF4	Crystal Structure of trypsin-vasopressin complex 分子名称: CALCIUM ION, Trypsin, Vasopressin 著者 Syed Ibrahim, B, Pattabhi, V. 登録日 2004-12-30 公開日 2005-05-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Trypsin inhibition by a Peptide hormone: crystal structure of trypsin-vasopressin complex J.Mol.Biol., 348, 2005
1BTP	UNIQUE BINDING OF A NOVEL SYNTHETIC INHIBITOR, N-[3-[4-[4-(AMIDINOPHENOXY)-CARBONYL]PHENYL]-2-METHYL-2-PROPENOYL]-N-ALLYLGLYCINE METHANESULFONATE TO BOVINE TRYPSIN, REVEALED BY THE CRYSTAL STRUCTURE OF THE COMPLEX 分子名称: BETA-TRYPSIN, CALCIUM ION 著者 Odagaki, Y, Nakai, H, Senokuchi, K, Kawamura, M, Hamanaka, N, Nakamura, M, Tomoo, K, Ishida, T. 登録日 1995-08-11 公開日 1996-01-29 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Unique binding of a novel synthetic inhibitor, N-[3-[4-[4-(amidinophenoxy)carbonyl]phenyl]-2-methyl-2-propenoyl]- N-allylglycine methanesulfonate, to bovine trypsin, revealed by the crystal structure of the complex. Biochemistry, 34, 1995
1AVU	TRYPSIN INHIBITOR FROM SOYBEAN (STI) 分子名称: TRYPSIN INHIBITOR 著者 Song, H.K, Suh, S.W. 登録日 1997-09-20 公開日 1998-10-28 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. J.Mol.Biol., 275, 1998
1MAY	BETA-TRYPSIN PHOSPHONATE INHIBITED 分子名称: BETA-TRYPSIN, CALCIUM ION, [N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE 著者 Bertrand, J, Oleksyszyn, J, Kam, C, Boduszek, B, Presnell, S, Plaskon, R, Suddath, F, Powers, J, Williams, L. 登録日 1996-02-06 公開日 1996-10-14 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry, 35, 1996
1MAX	BETA-TRYPSIN PHOSPHONATE INHIBITED 分子名称: BETA-TRYPSIN, CALCIUM ION, [N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE 著者 Bertrand, J, Oleksyszyn, J, Kam, C, Boduszek, B, Presnell, S, Plaskon, R, Suddath, F, Powers, J, Williams, L. 登録日 1996-02-06 公開日 1996-10-14 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry, 35, 1996
1XVM	Trypsin from Fusarium oxysporum- room temperature to atomic resolution 分子名称: Trypsin, substrate tripeptide GLY-ALA-ARG 著者 Schmidt, A, Lamzin, V.S. 登録日 2004-10-28 公開日 2005-07-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Extraction of functional motion in trypsin crystal structures. Acta Crystallogr.,Sect.D, 61, 2005
1CHG	CHYMOTRYPSINOGEN,2.5 ANGSTROMS CRYSTAL STRUCTURE, COMPARISON WITH ALPHA-CHYMOTRYPSIN,AND IMPLICATIONS FOR ZYMOGEN ACTIVATION 分子名称: CHYMOTRYPSINOGEN A 著者 Freer, S.T, Kraut, J, Robertus, J.D, Wright, H.T, Xuong, N.H. 登録日 1975-03-01 公開日 1976-11-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Chymotrypsinogen: 2.5-angstrom crystal structure, comparison with alpha-chymotrypsin, and implications for zymogen activation. Biochemistry, 9, 1970
1OXG	Crystal structure of a complex formed between organic solvent treated bovine alpha-chymotrypsin and its autocatalytically produced highly potent 14-residue peptide at 2.2 resolution 分子名称: Chymotrypsinogen A, SULFATE ION 著者 Singh, N, Jabeen, T, Sharma, S, Roy, I, Gupta, M.N, Bilgrami, S, Singh, T.P. 登録日 2003-04-02 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution. Febs J., 272, 2005
1TIH	TRYPSIN INHIBITOR (T1) FROM NICOTIANA ALATA 分子名称: TRYPSIN INHIBITOR T1 著者 Nielsen, K.J, Heath, R.L, Anderson, M.A, Craik, D.J. 登録日 1995-08-03 公開日 1995-10-15 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Structures of a series of 6-kDa trypsin inhibitors isolated from the stigma of Nicotiana alata. Biochemistry, 34, 1995

 

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