7VNN
| Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with long stem | 分子名称: | ADP-ribosylating binary toxin binding subunit CdtB, CALCIUM ION, CdtA | 著者 | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | 登録日 | 2021-10-11 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile. Nat Commun, 13, 2022
|
|
7VNJ
| Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with short stem | 分子名称: | ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosyltransferase enzymatic component, CALCIUM ION | 著者 | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | 登録日 | 2021-10-11 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile. Nat Commun, 13, 2022
|
|
7YVQ
| Complex structure of Clostridioides difficile binary toxin folded CDTa-bound CDTb-pore (short). | 分子名称: | ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION | 著者 | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | 登録日 | 2022-08-19 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile. Nat Commun, 13, 2022
|
|
7YVS
| Complex structure of Clostridioides difficile binary toxin unfolded CDTa-bound CDTb-pore (short). | 分子名称: | ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION | 著者 | Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H. | 登録日 | 2022-08-19 | 公開日 | 2022-10-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile. Nat Commun, 13, 2022
|
|
6X41
| |
6X6R
| Crystal structure of C.difficile ribosyltransferase CDTa in complex with pCl-phenylthioDADMeImmA | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, ADP-ribosyltransferase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Pozharski, E. | 登録日 | 2020-05-29 | 公開日 | 2021-10-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Crystal structure of C.difficile ribosyltransferase CDTa in complex with pCl-phenylthioDADMeImmA To Be Published
|
|
6X6W
| |
6X6X
| |
6X6V
| |
6V1S
| Structure of the Clostridioides difficile transferase toxin | 分子名称: | ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION | 著者 | Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B. | 登録日 | 2019-11-21 | 公開日 | 2020-03-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6KLO
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem | 分子名称: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | 登録日 | 2019-07-30 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
|
|
6KLW
| Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem | 分子名称: | CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib | 著者 | Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H. | 登録日 | 2019-07-30 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex. Nat.Struct.Mol.Biol., 27, 2020
|
|
6GNK
| Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form bound to Carba-NAD | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 14-3-3 protein beta/alpha, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H. | 登録日 | 2018-05-31 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9, 2018
|
|
6GNJ
| Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form in complex with STO1101 | 分子名称: | 14-3-3 protein beta/alpha, 3-(12-oxidanylidene-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9-trien-10-yl)propanoic acid, Exoenzyme S | 著者 | Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H. | 登録日 | 2018-05-31 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9, 2018
|
|
6GN0
| Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form | 分子名称: | 14-3-3 protein beta/alpha, Exoenzyme S | 著者 | Karlberg, T, Pinto, A.F, Hornyak, P, Nareoja, K, Schuler, H. | 登録日 | 2018-05-29 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9, 2018
|
|
6GNN
| Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101 | 分子名称: | 14-3-3 protein beta/alpha, 3-(12-oxidanylidene-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9-trien-10-yl)propanoic acid, Exoenzyme T | 著者 | Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H. | 登録日 | 2018-05-31 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.79 Å) | 主引用文献 | 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9, 2018
|
|
6GN8
| Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 14-3-3 protein beta/alpha, Exoenzyme S | 著者 | Karlberg, T, Pinto, A.F, Hornyak, P, Thorsell, A.G, Nareoja, K, Schuler, H. | 登録日 | 2018-05-30 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9, 2018
|
|
5URP
| Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae | 分子名称: | GLYCEROL, Toxin 2A | 著者 | Ravulapalli, R, Heney, K, Ebeling, J, Genersch, E, Merrill, A.R. | 登録日 | 2017-02-12 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural and functional characterization of Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae Environ.Microbiol., 2017
|
|
5WU0
| Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | 登録日 | 2016-12-15 | 公開日 | 2017-03-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
|
|
5WTZ
| Crystal structure of C. perfringens iota-like enterotoxin CPILE-a with NAD+ | 分子名称: | Binary enterotoxin of Clostridium perfringens component a, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | 登録日 | 2016-12-15 | 公開日 | 2017-03-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
|
|
5GTT
| Crystal structure of C. perfringens iota-like enterotoxin CPILE-a | 分子名称: | 1,2-ETHANEDIOL, Binary enterotoxin of Clostridium perfringens component a | 著者 | Toniti, W, Yoshida, T, Tsurumura, T, Irikura, D, Tsuge, H. | 登録日 | 2016-08-23 | 公開日 | 2017-03-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Crystal structure and structure-based mutagenesis of actin-specific ADP-ribosylating toxin CPILE-a as novel enterotoxin PLoS ONE, 12, 2017
|
|
5H04
| Crystal structure of an ADP-ribosylating toxin BECa of a novel binary enterotoxin of C. perfringens with NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | 著者 | Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S. | 登録日 | 2016-10-03 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.825 Å) | 主引用文献 | Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens. Biochem.Biophys.Res.Commun., 480, 2016
|
|
5H03
| Crystal structure of an ADP-ribosylating toxin BECa from C. perfringens | 分子名称: | Binary enterotoxin of Clostridium perfringens component a | 著者 | Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S. | 登録日 | 2016-10-03 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens. Biochem.Biophys.Res.Commun., 480, 2016
|
|
4XZK
| |
4YC0
| |