6GNJ

Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form in complex with STO1101

Summary for 6GNJ

• Entry DOI: 10.2210/pdb6gnj/pdb
• Related: 6GN0 6GN8
• Descriptor: 14-3-3 protein beta/alpha, Exoenzyme S, 3-(12-oxidanylidene-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9-trien-10-yl)propanoic acid (3 entities in total)
• Functional Keywords: exos, pseudomonas aeruginosa, adp-ribosylation, nad, toxin
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 82636.35

Authors

Karlberg, T.,Pinto, A.F.,Hornyak, P.,Thorsell, A.G.,Nareoja, K.,Schuler, H. (deposition date: 2018-05-31, release date: 2018-09-26, Last modification date: 2024-01-17)

• Primary citation: Karlberg, T.,Hornyak, P.,Pinto, A.F.,Milanova, S.,Ebrahimi, M.,Lindberg, M.,Pullen, N.,Nordstrom, A.,Loverli, E.,Caraballo, R.,Wong, E.V.,Nareoja, K.,Thorsell, A.G.,Elofsson, M.,De La Cruz, E.M.,Bjorkegren, C.,Schuler, H.; 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.; Nat Commun, 9:3785-3785, 2018; PubMed: 30224724; DOI: 10.1038/s41467-018-06194-1

Experimental method

X-RAY DIFFRACTION (3.24 Å)