4PLZ
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![BU of 4plz by Molmil](/molmil-images/mine/4plz) | Crystal structure of Plasmodium falciparum lactate dehydrogenase mutant W107fA. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase, OXAMIC ACID | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-20 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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1T2D
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![BU of 1t2d by Molmil](/molmil-images/mine/1t2d) | Plasmodium falciparum lactate dehydrogenase complexed with NAD+ and oxalate | 分子名称: | GLYCEROL, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. | 登録日 | 2004-04-21 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004
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4PLG
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![BU of 4plg by Molmil](/molmil-images/mine/4plg) | Crystal structure of ancestral apicomplexan lactate dehydrogenase with oxamate. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ... | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-16 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.192 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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4UUL
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![BU of 4uul by Molmil](/molmil-images/mine/4uul) | |
4H7P
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![BU of 4h7p by Molmil](/molmil-images/mine/4h7p) | |
5HS4
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![BU of 5hs4 by Molmil](/molmil-images/mine/5hs4) | Plasmdoium Vivax Lactate dehydrogenase | 分子名称: | L-lactate dehydrogenase | 著者 | Choi, S.J, Ban, C. | 登録日 | 2016-01-25 | 公開日 | 2016-10-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.339 Å) | 主引用文献 | Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
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4PLF
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![BU of 4plf by Molmil](/molmil-images/mine/4plf) | Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ... | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-16 | 公開日 | 2014-07-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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5NUE
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![BU of 5nue by Molmil](/molmil-images/mine/5nue) | Cytosolic Malate Dehydrogenase 1 (peroxide-treated) | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ETHOXYETHANOL, ... | 著者 | Young, D, Messens, J, Huang, J, Reichheld, J.-P. | 登録日 | 2017-04-29 | 公開日 | 2018-02-28 | 最終更新日 | 2018-07-04 | 実験手法 | X-RAY DIFFRACTION (1.35000277 Å) | 主引用文献 | Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
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4UUM
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![BU of 4uum by Molmil](/molmil-images/mine/4uum) | |
3HHP
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![BU of 3hhp by Molmil](/molmil-images/mine/3hhp) | |
4BGU
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![BU of 4bgu by Molmil](/molmil-images/mine/4bgu) | 1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... | 著者 | Talon, R, Madern, D, Girard, E. | 登録日 | 2013-03-28 | 公開日 | 2014-04-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.487 Å) | 主引用文献 | Insight Into Structural Evolution of Extremophilic Proteins To be Published
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4I1I
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![BU of 4i1i by Molmil](/molmil-images/mine/4i1i) | |
2A94
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![BU of 2a94 by Molmil](/molmil-images/mine/2a94) | Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH. | 分子名称: | ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase | 著者 | Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L. | 登録日 | 2005-07-11 | 公開日 | 2006-01-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH. Biochemistry, 44, 2005
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4PLC
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![BU of 4plc by Molmil](/molmil-images/mine/4plc) | Crystal structure of ancestral apicomplexan lactate dehydrogenase with malate. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ... | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-16 | 公開日 | 2014-07-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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4TVO
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![BU of 4tvo by Molmil](/molmil-images/mine/4tvo) | |
5UJK
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![BU of 5ujk by Molmil](/molmil-images/mine/5ujk) | |
6KA1
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![BU of 6ka1 by Molmil](/molmil-images/mine/6ka1) | |
5W8J
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![BU of 5w8j by Molmil](/molmil-images/mine/5w8j) | Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 | 分子名称: | 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Lukacs, C.M, Moulin, A. | 登録日 | 2017-06-21 | 公開日 | 2018-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
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3NEP
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![BU of 3nep by Molmil](/molmil-images/mine/3nep) | |
7DBJ
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![BU of 7dbj by Molmil](/molmil-images/mine/7dbj) | Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046 | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase B chain, ... | 著者 | Sogabe, S, Miwa, M. | 登録日 | 2020-10-20 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Identification of the first highly selective inhibitor of human lactate dehydrogenase B. Sci Rep, 11, 2021
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5NQB
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5W8K
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![BU of 5w8k by Molmil](/molmil-images/mine/5w8k) | Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 and NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{3-(3,4-difluorophenyl)-5-hydroxy-4-[(4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid, GLYCEROL, ... | 著者 | Lukacs, C.M, Dranow, D.M. | 登録日 | 2017-06-21 | 公開日 | 2018-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). J. Med. Chem., 60, 2017
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2X8L
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![BU of 2x8l by Molmil](/molmil-images/mine/2x8l) | |
1PZG
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![BU of 1pzg by Molmil](/molmil-images/mine/1pzg) | |
4PLT
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![BU of 4plt by Molmil](/molmil-images/mine/4plt) | Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate. | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, malate dehydrogenase | 著者 | Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L. | 登録日 | 2014-05-19 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3, 2014
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