PDB: 82 件ウェブページステータス検索Chemie searchBIRD

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4Z4D	Human Argonaute2 Bound to t1-G Target RNA 分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2015-04-02 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife, 4, 2015
6T5T	Crystal structure of Archaeoglobus fulgidus Argonaute protein with cognate DNA oligoduplex 5'-pATTGTGGCCACAAT 分子名称: 5'-D(*AP*TP*TP*GP*TP*GP*GP*CP*CP*AP*CP*AP*AP*TP)-3', BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Grazulis, S, Zaremba, M. 登録日 2019-10-17 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7003 Å) 主引用文献 Crystal structure of Archaeoglobus fulgidus Argonaute protein with cognate DNA oligoduplex 5'-pATTGTGGCCACAAT To be published
4KRE	Structure of Human Argonaute-1 bound to endogenous Sf9 RNA 分子名称: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3') 著者 Faehnle, C.R, Elkayam, E, Joshua-Tor, L. 登録日 2013-05-16 公開日 2013-06-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.754 Å) 主引用文献 The making of a slicer: activation of human argonaute-1. Cell Rep, 3, 2013
6TUO	Crystal structure of Archaeoglobus fulgidus Argonaute protein with cognate DNA oligoduplex 5'-pATTGTACGTACAAT 分子名称: 5'-D(*AP*TP*TP*GP*TP*AP*CP*GP*TP*AP*CP*AP*AP*TP)-3', BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Grazulis, S, Zaremba, M. 登録日 2020-01-07 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Archaeoglobus fulgidus Argonaute protein with cognate DNA oligoduplex 5'-pATTGTACGTACAAT To be published
4Z4E	Human Argonaute2 Bound to t1-U Target RNA 分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2015-04-02 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife, 4, 2015
4W5O	The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-9 分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ... 著者 Schirle, N.T, MacRae, I.J. 登録日 2014-08-18 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Gene regulation. Structural basis for microRNA targeting. Science, 346, 2014
6D92	Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-A non-canonical pair at position 3 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*AP*AP*AP*C)-3'), ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-27 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018
6D95	Ternary RsAgo Complex with Guide RNA Paired and Target DNA containing A8-A8' Non-Canonical Pair 分子名称: DNA 24-Mer, MAGNESIUM ION, RNA (5'-R(P*UP*UP*AP*CP*UP*GP*CP*AP*CP*AP*GP*GP*UP*GP*AP*CP*GP*A)-3'), ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-27 公開日 2018-08-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018
2YHA	Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains 分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION 著者 Boland, A, Weichenrieder, O. 登録日 2011-04-27 公開日 2011-06-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein Proc.Natl.Acad.Sci.USA, 108, 2011
6XUP	Archaeoglobus fulgidus Argonaute protein with DNA oligoduplex 5'-pATCGTGGCCACGAT 分子名称: 5'-D(*AP*TP*CP*GP*TP*GP*GP*CP*CP*AP*CP*GP*AP*TP)-3', BETA-MERCAPTOETHANOL, CACODYLATE ION, ... 著者 Grazulis, S, Zaremba, M. 登録日 2020-01-20 公開日 2021-02-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Archaeoglobus fulgidus Argonaute protein with DNA oligoduplex 5'-pATCGTGGCCACGAT To be published
2W42	THE STRUCTURE OF A PIWI PROTEIN FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH A 16NT DNA DUPLEX. 分子名称: 5'-D(*GP*TP*CP*GP*AP*AP*TP*TP)-3', 5'-D(*TP*TP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ... 著者 Parker, J.S, Roe, S.M, Barford, D. 登録日 2008-11-19 公開日 2008-12-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enhancement of the Seed-Target Recognition Step in RNA Silencing by a Piwi-Mid Domain Protein Mol.Cell, 33, 2009
6OON	Human Argonaute4 bound to guide RNA 分子名称: Protein argonaute-4, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3') 著者 Park, M.S, Brackbill, J.A, Nakanishi, K. 登録日 2019-04-23 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters. Mol.Cell, 75, 2019
6XU0	Archaeoglobus fulgidus Argonaute protein with DNA oligoduplex 5'-pATCGTGGCCACGAT 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 5'-D(*AP*TP*CP*GP*TP*GP*GP*CP*CP*AP*CP*GP*AP*TP)-3', BETA-MERCAPTOETHANOL, ... 著者 Grazulis, S, Zaremba, M. 登録日 2020-01-17 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Archaeoglobus fulgidus Argonaute protein with DNA oligoduplex 5'-pATCGTGGCCACGAT To be published
1W9H	The Structure of a Piwi protein from Archaeoglobus fulgidus. 分子名称: CADMIUM ION, CHLORIDE ION, HYPOTHETICAL PROTEIN AF1318, ... 著者 Parker, J.S, Roe, S.M, Barford, D. 登録日 2004-10-13 公開日 2005-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of a Piwi Protein Suggests Mechanisms for Sirna Recognition and Slicer Activity Embo J., 23, 2004
5AWH	Rhodobacter sphaeroides Argonaute in complex with guide RNA/target DNA heteroduplex 分子名称: DNA (5'-D(*CP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*A)-3'), MAGNESIUM ION, RNA (5'-D(P*UP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3'), ... 著者 Miyoshi, T, Ito, K, Murakami, R, Uchiumi, T. 登録日 2015-07-03 公開日 2016-07-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute. Nat Commun, 7, 2016
6D9K	Ternary RsAgo Complex with Guide RNA and Target DNA Containing A-G Non-canonical Pair 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*GP*GP*CP*AP*GP*TP*AP*AP*C)-3'), ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-30 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018
5THE	Crystal structure of the C-terminal lobe of a budding yeast Argonaute 分子名称: RNA (5'-R(P*UP*AP*AP*AP*AP*AP*AP*A)-3'), Uncharacterized protein 著者 Dayeh, D.M, Nakanishi, K. 登録日 2016-09-29 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Structural and functional analyses reveal the contributions of the C- and N-lobes of Argonaute protein to selectivity of RNA target cleavage. J. Biol. Chem., 293, 2018
6D8P	Ternary RsAgo Complex Containing Guide RNA Paired with Target DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CACODYLATE ION, ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018
4KRF	Structure of Human Argonaute-1 let-7 complex 分子名称: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3') 著者 Faehnle, C.R, Elkayam, E, Joshua-Tor, L. 登録日 2013-05-16 公開日 2013-06-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 The making of a slicer: activation of human argonaute-1. Cell Rep, 3, 2013
6D8F	RsAgo Ternary Complex with Guide RNA and Target DNA Containing T-T Bulge Within the Seed Segment 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*TP*TP*TP*AP*AP*C)-3'), ... 著者 Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J. 登録日 2018-04-26 公開日 2018-07-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA. Cell Rep, 24, 2018
5KI6	Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1 分子名称: PHENOL, Protein argonaute-2, miR-122 著者 Schirle, N.T, MacRae, I.J. 登録日 2016-06-16 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Structure-Guided Control of siRNA Off-Target Effects. J.Am.Chem.Soc., 138, 2016
2BGG	The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex. 分子名称: 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ... 著者 Parker, J.S, Roe, S.M, Barford, D. 登録日 2004-12-22 公開日 2005-03-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex Nature, 434, 2005
6CBD	Crystal Structure of Human Argonaute2 Bound to Three Tryptophans 分子名称: Guide RNA, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-02-02 公開日 2018-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Phase Transitions in the Assembly and Function of Human miRISC. Cell, 173, 2018
1U04	Crystal structure of full length Argonaute from Pyrococcus furiosus 分子名称: hypothetical protein PF0537 著者 Song, J.J, Smith, S.K, Hannon, G.J, Joshua-Tor, L. 登録日 2004-07-12 公開日 2004-08-17 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity Science, 305, 2004
4F3T	Human Argonaute-2 - miR-20a complex 分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*AP*AP*AP*GP*UP*GP*CP*UP*UP*AP*UP*AP*GP*UP*G*CP*AP*GP*G)-3') 著者 Elkayam, E, Kuhn, C.-D, Tocilj, A, Joshua-Tor, L. 登録日 2012-05-09 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The Structure of Human Argonaute-2 in Complex with miR-20a. Cell(Cambridge,Mass.), 150, 2012

 

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