PDB: 657 件ウェブページステータス検索Chemie searchBIRD

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1D5G	SOLUTION STRUCTURE OF THE PDZ2 DOMAIN FROM HUMAN PHOSPHATASE HPTP1E COMPLEXED WITH A PEPTIDE 分子名称: HUMAN PHOSPHATASE HPTP1E, PEPTIDE FADSEADENEQVSAV 著者 Kozlov, G, Gehring, K, Ekiel, I. 登録日 1999-10-07 公開日 2002-07-24 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions J.Mol.Biol., 320, 2002
8OEP	Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide 分子名称: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 著者 Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. 登録日 2023-03-11 公開日 2023-05-10 最終更新日 2023-05-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
5JXB	PSD-95 extended PDZ3 in complex with SynGAP PBM 分子名称: Disks large homolog 4,SynGAP 著者 Shang, Y, Zhang, M. 登録日 2016-05-13 公開日 2016-09-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity. Cell, 166, 2016
5K4F	CAL PDZ mutant C319A with a peptide 分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 peptide 著者 Zhao, Y, Madden, D.R. 登録日 2016-05-20 公開日 2017-08-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 CAL PDZ domain mutant with a peptide To Be Published
7CQF	Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ... 著者 Yamagata, A, Fukai, S. 登録日 2020-08-10 公開日 2021-01-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention. Proc.Natl.Acad.Sci.USA, 118, 2021
8GI4	Crystal structure of human LIMK2 PDZ domain 分子名称: LIM domain kinase 2 著者 Casanova Sepulveda, G, Boggon, T.J. 登録日 2023-03-13 公開日 2023-12-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Autoregulation of the LIM kinases by their PDZ domain. Nat Commun, 14, 2023
7D6F	The crystal structure of ARMS-PBM/MAGI2-PDZ4 分子名称: GLYCEROL, Kinase D-interacting substrate of 220 kDa, Membrane-associated guanylate kinase, ... 著者 Ye, J, Zhang, Y, Zhong, Z, Wang, C. 登録日 2020-09-30 公開日 2020-11-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Crystal structure of the PDZ4 domain of MAGI2 in complex with PBM of ARMS reveals a canonical PDZ recognition mode. Neurochem.Int., 149, 2021
8HCK	NMR fragment-based screening against the two PDZ do-mains of MDA-9 分子名称: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, GLYCEROL, SULFATE ION, ... 著者 Tang, H. 登録日 2022-11-01 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 NMR fragment-based screening against the two PDZ do-mains of MDA-9 To Be Published
8HU2	Rattus Syntenin-1 PDZ domain with inhibitor 分子名称: (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1 著者 Heo, Y, Lee, J, Yun, J.H, Lee, W. 登録日 2022-12-22 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution. To Be Published
7E0B	The crystal structure of sorting nexin 27 and PBM complex 分子名称: PBM, Sorting nexin-27 著者 Shang, G.J, Qi, J.X. 登録日 2021-01-27 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry. Proc.Natl.Acad.Sci.USA, 119, 2022
5TYT	Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide 分子名称: Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera 著者 Spellmon, N, Holcomb, J, Niu, A, Choudhary, V, Sun, X, Brunzelle, J, Li, C, Yang, Z. 登録日 2016-11-21 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.398 Å) 主引用文献 Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. Biochem. Biophys. Res. Commun., 485, 2017
5V6B	Crystal structure of GIPC1 分子名称: PDZ domain-containing protein GIPC1 著者 Shang, G, Zhang, X. 登録日 2017-03-16 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex. Elife, 6, 2017
4E35	Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide 分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL50 peptide 著者 Amacher, J.F, Madden, D.R. 登録日 2012-03-09 公開日 2012-12-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
4E34	Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide 分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ... 著者 Amacher, J.F, Beck, T, Madden, D.R. 登録日 2012-03-09 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.395 Å) 主引用文献 Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
4E3B	Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide 分子名称: Tax1-binding protein 3, iCAL50 peptide 著者 Amacher, J.F, Madden, D.R. 登録日 2012-03-09 公開日 2012-12-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
4F8K	Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1 分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor 著者 Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P. 登録日 2012-05-17 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1. Plos One, 8, 2013
6AK2	Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 分子名称: Syntenin-1, peptide inhibitor KSL-128018 著者 Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. 登録日 2018-08-29 公開日 2019-09-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.868 Å) 主引用文献 A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem., 64, 2021
6AR4	Crystal structure of PICK1 in complex with the small molecule inhibitor 1o 分子名称: N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein 著者 Marcotte, D. 登録日 2017-08-21 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Sci Rep, 8, 2018
6BJO	PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. 分子名称: (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6BJN	PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV 分子名称: PRKCA-binding protein 著者 Marcotte, D.J. 登録日 2017-11-06 公開日 2018-01-10 最終更新日 2018-02-28 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein Sci., 27, 2018
6BXG	1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. 分子名称: CHLORIDE ION, IODIDE ION, LEU-ILE-ALA, ... 著者 Minasov, G, Shuvalova, L, Filippova, E.V, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-12-18 公開日 2018-01-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 1.45 Angstrom Resolution Crystal Structure of PDZ domain of Carboxy-Terminal Protease from Vibrio cholerae in Complex with Peptide. To Be Published
1G9O	FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR 分子名称: NHE-RF 著者 Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. 登録日 2000-11-26 公開日 2001-05-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
7VZE	Crystal structure of PTPN4 PDZ bound to the PBM of HPV16 E6 分子名称: Tyrosine-protein phosphatase non-receptor type 4, the PDZ-binding motif of HPV16 E6 著者 Lee, H.S, Yun, H.-Y, Ku, B. 登録日 2021-11-16 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.882 Å) 主引用文献 Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein. J.Microbiol, 60, 2022
1GM1	Second PDZ Domain (PDZ2) of PTP-BL 分子名称: PROTEIN TYROSINE PHOSPHATASE 著者 Walma, T, Tessari, M, Aelen, J, Schepens, J, Hendriks, W, Vuister, G.W. 登録日 2001-09-06 公開日 2002-03-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL. J. Mol. Biol., 316, 2002
1GQ5	Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR 分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50 著者 Karthikeyan, S, Leung, T, Ladias, J.A.A. 登録日 2001-11-20 公開日 2002-11-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors J.Biol.Chem., 277, 2002

 

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