PDB: 145 件ウェブページステータス検索Chemie searchBIRD

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1F57	CARBOXYPEPTIDASE A COMPLEX WITH D-CYSTEINE AT 1.75 A 分子名称: CARBOXYPEPTIDASE A, D-CYSTEINE, ZINC ION 著者 van Aalten, D.M, Chong, C.R, Joshua-Tor, L. 登録日 2000-06-13 公開日 2000-09-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes. Biochemistry, 39, 2000
8CPA	COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY 分子名称: CARBOXYPEPTIDASE A, O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE, ZINC ION 著者 Kim, H, Lipscomb, W.N. 登録日 1991-05-21 公開日 1994-01-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Comparison of the structures of three carboxypeptidase A-phosphonate complexes determined by X-ray crystallography. Biochemistry, 30, 1991
4F8Z	Carboxypeptidase T with Boc-Leu 分子名称: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... 著者 Timofeev, V.I, Kuznetsov, S.A, Akparov, V.K, Kuranova, I.P. 登録日 2012-05-18 公開日 2013-05-22 最終更新日 2015-09-30 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine. Biochemistry Mosc., 78, 2013
7Q87	Carboxypeptidase T with (S)-3-phenyllactic acid 分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CALCIUM ION, Carboxypeptidase T, ... 著者 Timofeev, V.I, Akparov, V.K, Shevtsov, M.B, Kuranova, I.P. 登録日 2021-11-10 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Carboxypeptidase T with (S)-3-phenyllactic acid To Be Published
2JEW	Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB 分子名称: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION 著者 Brown, D.G, Moore, R.S. 登録日 2007-01-24 公開日 2007-11-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. J. Med. Chem., 50, 2007
4Z65	Carboxypeptidase B with Sulphamoil Arginine 分子名称: Carboxypeptidase B, N~2~-sulfamoyl-L-arginine, ZINC ION 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2015-04-03 公開日 2015-10-14 最終更新日 2015-10-28 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structure of the complex of carboxypeptidase B and N-sulfamoyl-L-arginine. Acta Crystallogr.,Sect.F, 71, 2015
6Z28	Carboxypeptidase T mutant L254N with N-sulfamoyl-L-glutamic acid 分子名称: CALCIUM ION, Carboxypeptidase T, N-sulfamoyl-L-glutamic acid, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2020-05-15 公開日 2020-05-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 CARBOXYPEPTIDASE T MUTANT L254N WITH WITH N-SULFAMOYL-L-GLUT To Be Published
5ZEQ	Carboxypeptidase B in complex with DD28 分子名称: (2~{S})-2-[(6-azanyl-5-chloranyl-pyridin-3-yl)methyl]-3-selanyl-propanoic acid, CACODYLATE ION, Carboxypeptidase B, ... 著者 Itoh, T, Yoshimoto, N, Yamamoto, K. 登録日 2018-02-27 公開日 2018-06-20 最終更新日 2018-07-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the selective inhibition of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) by a selenium-containing inhibitor with chloro-aminopyridine as a basic group Bioorg. Med. Chem. Lett., 28, 2018
6I6Z	Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Tyr-Ala-Y(PO2CH2)-homoPhe-OH 分子名称: (2S)-2-{[(S)-{(1R)-1-[(N-acetyl-L-tyrosyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, Carboxypeptidase A1, ZINC ION 著者 Gallego, P, Reverter, D. 登録日 2018-11-15 公開日 2018-12-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical Probes. J. Med. Chem., 62, 2019
8QVO	L211Q, L254N, T262G mutant of carboxypeptidase T from Thermoactinomyces vulgaris 分子名称: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... 著者 Timofeev, V.I, Dorovatovskii, P.V, Lazarenko, V.A, Akparov, V.K, Kuranova, I.P. 登録日 2023-10-18 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 L211Q, L254N, T262G mutant of carboxypeptidase T from Thermoactinomyces vulgaris To Be Published
6CPA	CRYSTAL STRUCTURE OF THE COMPLEX OF CARBOXYPEPTIDASE A WITH A STRONGLY BOUND PHOSPHONATE IN A NEW CRYSTALLINE FORM: COMPARISON WITH STRUCTURES OF OTHER COMPLEXES 分子名称: CARBOXYPEPTIDASE A, O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID, ZINC ION 著者 Kim, H, Lipscomb, W.N. 登録日 1990-02-15 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the complex of carboxypeptidase A with a strongly bound phosphonate in a new crystalline form: comparison with structures of other complexes. Biochemistry, 29, 1990
5CPA	REFINED CRYSTAL STRUCTURE OF CARBOXYPEPTIDASE A AT 1.54 ANGSTROMS RESOLUTION. 分子名称: CARBOXYPEPTIDASE A, ZINC ION 著者 Lipscomb, W.N. 登録日 1982-05-06 公開日 1982-07-29 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Refined crystal structure of carboxypeptidase A at 1.54 A resolution. J.Mol.Biol., 168, 1983
2RFH	Crystal Structure Analysis of CPA-2-benzyl-3-nitropropanoic acid complex 分子名称: (2R)-2-benzyl-3-nitropropanoic acid, Carboxypeptidase A1, ZINC ION 著者 Wang, S.-F, Zeng, Z.-H. 登録日 2007-09-29 公開日 2008-04-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A Bioorg.Med.Chem., 16, 2008
5J1Q	Carboxypeptidase B with Sulphamoil Phenylalanine 分子名称: Carboxypeptidase B, PHENYLALANINE-N-SULFONAMIDE, ZINC ION 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2016-03-29 公開日 2017-04-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Carboxypeptidase B with Sulphamoil Phenylalanine To Be Published
5JC6	Carboxypeptidase B with 2-nd zinc and acetate ion 分子名称: ACETATE ION, Carboxypeptidase B, ZINC ION 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2016-04-14 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of the carboxypeptidase B complex with N-sulfamoyl-L-phenylalanine - a transition state analog of non-specific substrate. J. Biomol. Struct. Dyn., 36, 2018
4OKO	Crystal structure of Francisella tularensis REP34 (Rapid Encystment Phenotype Protein 34 KDa) 分子名称: ACETATE ION, Rapid Encystment Phenotype Protein 34 KDa, ZINC ION 著者 Feld, G.K, Segelke, B.W, Corzett, M.H, Hunter, M.S, Frank, M, Rasley, A. 登録日 2014-01-22 公開日 2014-09-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.053 Å) 主引用文献 Structure and Function of REP34 Implicates Carboxypeptidase Activity in Francisella tularensis Host Cell Invasion. J.Biol.Chem., 289, 2014
7AQP	T262S, A251S, L254S, L211Q mutant of carboxypeptidase T from Thermoactinomyces vulgaris 分子名称: CALCIUM ION, Carboxypeptidase T, SULFATE ION, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2020-10-22 公開日 2020-12-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 T262S, A251S, L254S, L211Q mutant of carboxypeptidase T from Thermoactinomyces vulgaris To Be Published
7ARU	L254N mutant of carboxypeptidase T from Thermoactinomyces vulgaris N-sulfamoyl-L-valine 分子名称: (2~{S})-3-methyl-2-(sulfamoylamino)butanoic acid, CALCIUM ION, Carboxypeptidase T, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2020-10-26 公開日 2020-11-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 L254N mutant of carboxypeptidase T from Thermoactinomyces vulgaris N-sulfamoyl-L-valine To Be Published
2V77	Crystal Structure of Human Carboxypeptidase A1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ... 著者 Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J. 登録日 2007-07-27 公開日 2008-07-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid). Acta Crystallogr. D Biol. Crystallogr., D64, 2008
3PRT	Mutant of the Carboxypeptidase T 分子名称: CALCIUM ION, Carboxypeptidase T, GLYCEROL, ... 著者 Timofeev, V.I, Akparov, V.K, Grishin, A.M, Kuranova, I.P. 登録日 2010-11-30 公開日 2011-11-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献
3QNV	Carboxypeptidase T 分子名称: Carboxypeptidase T, GLYCEROL, SULFATE ION, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2011-02-09 公開日 2012-02-15 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Three-dimensional structure of recombinant carboxypeptidase T from Thermoactinomyces vulgaris without calcium ions Crystallography Reports, 56, 2011
5MRV	Crystal structure of human carboxypeptidase O in complex with NvCI 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase O, Metallocarboxypeptidase inhibitor, ... 著者 Garcia-Pardo, J, Garcia-Guerrero, M.C, Fernandez-Alvarez, R, Lyons, P, Aviles, F.X, Lorenzo, J, Reverter, D. 登録日 2016-12-27 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.854 Å) 主引用文献 Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6SN6	CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID 分子名称: CALCIUM ION, Carboxypeptidase T, N-sulfamoyl-L-glutamic acid, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2019-08-23 公開日 2019-10-09 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-GLUTAMIC ACID To Be Published
5LYF	Crystal structure of 1 in complex with tafCPB 分子名称: (2~{S})-6-azanyl-2-[[(2~{R})-1-[[(1~{R},2~{S},4~{S})-2-bicyclo[2.2.1]heptanyl]amino]-3-cyclohexyl-1-oxidanylidene-propan-2-yl]carbamoylamino]hexanoic acid, Carboxypeptidase B, ZINC ION 著者 Schreuder, H, Liesum, A, Loenze, P. 登録日 2016-09-28 公開日 2016-10-26 最終更新日 2016-12-21 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa). J. Med. Chem., 59, 2016
6T9Y	CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-LYSIN 分子名称: (2~{S})-6-azanyl-2-(sulfamoylamino)hexanoic acid, CALCIUM ION, Carboxypeptidase T, ... 著者 Timofeev, V.I, Akparov, V.K, Kuranova, I.P. 登録日 2019-10-29 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 CARBOXYPEPTIDASE T WITH N-SULFAMOYL-L-LYSIN To Be Published

 

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