8HPA
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![BU of 8hpa by Molmil](/molmil-images/mine/8hpa) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | 著者 | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | 登録日 | 2022-12-12 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structure of DNA replication machinery from human monkeypox virus To Be Published
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6TNZ
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![BU of 6tnz by Molmil](/molmil-images/mine/6tnz) | Human polymerase delta-FEN1-PCNA toolbelt | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-12-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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5IUD
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![BU of 5iud by Molmil](/molmil-images/mine/5iud) | |
6AS7
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![BU of 6as7 by Molmil](/molmil-images/mine/6as7) | CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ... | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | 登録日 | 2017-08-23 | 公開日 | 2018-03-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Activity and fidelity of human DNA polymerase alpha depend on primer structure. J. Biol. Chem., 293, 2018
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6P1H
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![BU of 6p1h by Molmil](/molmil-images/mine/6p1h) | Cryo-EM Structure of DNA Polymerase Delta Holoenzyme | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... | 著者 | Jain, R, Rice, W, Aggarwal, A.K. | 登録日 | 2019-05-19 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure and dynamics of eukaryotic DNA polymerase delta holoenzyme. Nat.Struct.Mol.Biol., 26, 2019
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2JGU
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7F4Y
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![BU of 7f4y by Molmil](/molmil-images/mine/7f4y) | Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*AP*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... | 著者 | Youn, H.-S, Park, J, An, J.Y, Lee, Y, Eom, S.H, Wang, J. | 登録日 | 2021-06-21 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69. Front Mol Biosci, 8, 2021
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2XHB
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![BU of 2xhb by Molmil](/molmil-images/mine/2xhb) | Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ... | 著者 | Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A. | 登録日 | 2010-06-14 | 公開日 | 2010-07-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues. Biochemistry, 49, 2010
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2ATQ
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![BU of 2atq by Molmil](/molmil-images/mine/2atq) | RB69 single-stranded DNA binding protein-DNA polymerase fusion | 分子名称: | DNA polymerase, GUANOSINE-5'-DIPHOSPHATE, ZINC ION, ... | 著者 | Sun, S, Geng, L, Shamoo, Y. | 登録日 | 2005-08-25 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Proteins, 65, 2006
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3IAY
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![BU of 3iay by Molmil](/molmil-images/mine/3iay) | Ternary complex of DNA polymerase delta | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Swan, M.K, Aggarwal, A.K. | 登録日 | 2009-07-15 | 公開日 | 2009-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta Nat.Struct.Mol.Biol., 16, 2009
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2VWJ
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![BU of 2vwj by Molmil](/molmil-images/mine/2vwj) | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. | 分子名称: | 5'-D(*AP*AP*UP*GP*GP*AP*GP*AP*CP*GP *GP*CP*TP*TP*TP*TP*GP*CP*CP*GP*TP*GP*TP*C)-3', DNA POLYMERASE, POTASSIUM ION | 著者 | Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. | 登録日 | 2008-06-25 | 公開日 | 2008-07-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
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6WYA
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![BU of 6wya by Molmil](/molmil-images/mine/6wya) | RTX (Reverse Transcription Xenopolymerase) in complex with a DNA duplex and dAMPNPP | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | 登録日 | 2020-05-12 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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9ENQ
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![BU of 9enq by Molmil](/molmil-images/mine/9enq) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | 著者 | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | 登録日 | 2024-03-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
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9ENP
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![BU of 9enp by Molmil](/molmil-images/mine/9enp) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | 著者 | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | 登録日 | 2024-03-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
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5EXR
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![BU of 5exr by Molmil](/molmil-images/mine/5exr) | Crystal structure of human primosome | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | 登録日 | 2015-11-24 | 公開日 | 2016-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
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6WYB
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![BU of 6wyb by Molmil](/molmil-images/mine/6wyb) | RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid | 分子名称: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, DNA polymerase, ... | 著者 | Choi, W.S, He, P, Pothukuchy, A, Gollihar, J, Ellington, A.D, Yang, W. | 登録日 | 2020-05-12 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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7LXD
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![BU of 7lxd by Molmil](/molmil-images/mine/7lxd) | Structure of yeast DNA Polymerase Zeta (apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Truong, C.D, Craig, T.A, Cui, G, Botuyan, M.V, Serkasevich, R.A, Chan, K.-Y, Mer, G, Chiu, P.-L, Kumar, R. | 登録日 | 2021-03-03 | 公開日 | 2021-06-30 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | 主引用文献 | Cryo-EM reveals conformational flexibility in apo DNA polymerase zeta. J.Biol.Chem., 297, 2021
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2VWK
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![BU of 2vwk by Molmil](/molmil-images/mine/2vwk) | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase variant | 分子名称: | DNA POLYMERASE, SODIUM ION, SULFATE ION | 著者 | Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. | 登録日 | 2008-06-26 | 公開日 | 2008-07-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
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4DTJ
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![BU of 4dtj by Molmil](/molmil-images/mine/4dtj) | RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddT/dA as the Penultimate Base-pair | 分子名称: | CALCIUM ION, DNA polymerase, DNA primer, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
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4DU3
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![BU of 4du3 by Molmil](/molmil-images/mine/4du3) | RB69 DNA Polymerase Ternary Complex with dDTP Opposite dT with 3-Deaza-adenine at the N-1 Position of Template Strand | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2012-02-21 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
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1D5A
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![BU of 1d5a by Molmil](/molmil-images/mine/1d5a) | CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM | 分子名称: | MAGNESIUM ION, PROTEIN (DNA POLYMERASE), SULFATE ION | 著者 | Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J. | 登録日 | 1999-10-06 | 公開日 | 2000-03-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of an archaebacterial DNA polymerase. Structure Fold.Des., 7, 1999
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5H12
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![BU of 5h12 by Molmil](/molmil-images/mine/5h12) | |
8QJ7
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![BU of 8qj7 by Molmil](/molmil-images/mine/8qj7) | |
1IH7
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![BU of 1ih7 by Molmil](/molmil-images/mine/1ih7) | High-Resolution Structure of Apo RB69 DNA Polymerase | 分子名称: | DNA POLYMERASE, GUANOSINE, POTASSIUM ION | 著者 | Franklin, M.C, Wang, J, Steitz, T.A. | 登録日 | 2001-04-18 | 公開日 | 2001-06-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
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7KC0
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![BU of 7kc0 by Molmil](/molmil-images/mine/7kc0) | Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... | 著者 | Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. | 登録日 | 2020-10-04 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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