2J9I
| Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens. | 分子名称: | GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1 | 著者 | Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G. | 登録日 | 2006-11-09 | 公開日 | 2006-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens. Structure, 14, 2006
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5DM3
| Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, L-glutamine synthetase | 著者 | Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2015-09-07 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Glutamine Synthetase from Chromohalobacter salexigens DSM 3043(Csal_0679, TARGET EFI-550015) with bound ADP To be published
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8WWU
| 1-naphthylamine GS in complex with AMP PNP | 分子名称: | Glutamine synthetase, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Zhang, S.T, Zhou, N.Y. | 登録日 | 2023-10-26 | 公開日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation To Be Published
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8WWV
| 1-naphthylamine GS in complex with ADP and MetSox-P | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... | 著者 | Zhang, S.T, Zhou, N.Y. | 登録日 | 2023-10-26 | 公開日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of the 1-naphthylamine biodegradation pathway reveals a glutamine synthetase-like protein that catalyzes 1-naphthylamine glutamylation To Be Published
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7V4H
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7CQU
| GmaS/ADP/MetSox-P complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MAGNESIUM ION, ... | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQX
| GmaS/ADP complex-Conformation 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQW
| GmaS/ADP complex-Conformation 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQQ
| GmaS in complex with AMPPNP and MetSox | 分子名称: | (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQL
| Apo GmaS without ligand | 分子名称: | Type III glutamate--ammonia ligase | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQN
| GmaS in complex with AMPPCP | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Type III glutamate--ammonia ligase | 著者 | Li, C.Y, Zhang, Y.Z. | 登録日 | 2020-08-11 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.962 Å) | 主引用文献 | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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3FKY
| Crystal structure of the glutamine synthetase Gln1deltaN18 from the yeast Saccharomyces cerevisiae | 分子名称: | CITRATE ANION, Glutamine synthetase | 著者 | He, Y.X, Gui, L, Liu, Y.Z, Du, Y, Zhou, Y.Y, Li, P, Zhou, C.Z. | 登録日 | 2008-12-18 | 公開日 | 2009-10-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly Proteins, 76, 2009
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5ZLI
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3NG0
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1LGR
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7W85
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2WHI
| Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor and L-methionine-S- sulfoximine phosphate. | 分子名称: | 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... | 著者 | Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2009-05-05 | 公開日 | 2009-09-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
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2WGS
| Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor. | 分子名称: | 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1 | 著者 | Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2009-04-27 | 公開日 | 2009-09-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
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4XYC
| NANOMOLAR INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE 1: SYNTHESIS, BIOLOGICAL EVALUATION AND X-RAY CRYSTALLOGRAPHIC STUDIES | 分子名称: | 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, Glutamine synthetase 1 | 著者 | Couturier, C, Silve, S, Morales, R, Ppessegue, B, Llopart, S, Nair, A, Bauer, A, Scheiper, B, poeverlein, c, Ganzhorn, A, Lagrange, S, Bacque, E. | 登録日 | 2015-02-02 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Nanomolar inhibitors of Mycobacterium tuberculosis glutamine synthetase 1: Synthesis, biological evaluation and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 25, 2015
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8FBP
| Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation | 分子名称: | Glutamine synthetase | 著者 | Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-11-29 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation To Be Published
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6PEW
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8PVG
| Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV | 分子名称: | Glutamine synthetase | 著者 | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | 登録日 | 2023-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
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3O6X
| Crystal Structure of the type III Glutamine Synthetase from Bacteroides fragilis | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ... | 著者 | van Rooyen, J.M, Belrhali, H, Abratt, V.R, Sewell, B.T. | 登録日 | 2010-07-29 | 公開日 | 2011-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface. Structure, 19, 2011
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2BVC
| Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... | 著者 | Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2005-06-23 | 公開日 | 2005-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights. Proc.Natl.Acad.Sci.USA, 102, 2005
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5ZLP
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