PDB: 1379 件ウェブページステータス検索Chemie searchBIRD

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9G9S	Crystal structure of PbdA bound to veratrate 分子名称: 3,4-dimethoxybenzoic acid, Cytochrome P450 CYP199, GLYCEROL, ... 著者 Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. 登録日 2024-07-25 公開日 2024-10-02 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates. J.Biol.Chem., 2024
9G9R	Crystal structure of PbdA bound to p-ethylbenzoate 分子名称: 4-ethylbenzoic acid, Cytochrome P450 CYP199, GLYCEROL, ... 著者 Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. 登録日 2024-07-25 公開日 2024-10-02 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates. J.Biol.Chem., 2024
9G9Q	Crystal structure of PbdA bound to p-methoxybenzoate. 分子名称: 4-METHOXYBENZOIC ACID, Cytochrome P450 CYP199, GLYCEROL, ... 著者 Hinchen, D.J, Wolf, M.E, Eltis, L.D, McGeehan, J.E. 登録日 2024-07-25 公開日 2024-10-02 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates. J.Biol.Chem., 2024
8W7G	Crystal structure of cytochrome P450 CYP161H12 from Amycolatopsis pretoriensis 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase 著者 Dong, L.B, Zhang, X.W, Pan, X.M, Li, F.R. 登録日 2023-08-30 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Explore the chemical space of Pentacyclic Triterpenoids: Mining Bacterial CYP450s for Aliphatic C-H Activation To Be Published
8X1W	CYP725A4 apo structure 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Taxadiene 5-alpha hydroxylase 著者 Chang, Z, Wang, Q. 登録日 2023-11-09 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Unraveling the Catalytic Mechanism of Taxadiene-5alpha-hydroxylase from Crystallography and Computational Analyses. Acs Catalysis, 14, 2024
8X3E	CYP725A4-Taxa-4,11-diene complex 分子名称: (1~{R},3~{R},8~{R})-4,8,12,15,15-pentamethyltricyclo[9.3.1.0^{3,8}]pentadeca-4,11-diene, PROTOPORPHYRIN IX CONTAINING FE, Taxadiene 5-alpha hydroxylase 著者 Chang, Z, Wang, Q. 登録日 2023-11-13 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Unraveling the Catalytic Mechanism of Taxadiene-5alpha-hydroxylase from Crystallography and Computational Analyses. Acs Catalysis, 14, 2024
9BBB	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, cobicistat 著者 Sevrioukova, I.F. 登録日 2024-04-05 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Interaction of CYP3A4 with the inhibitor cobicistat: Structural and mechanistic insights and comparison with ritonavir to be published
8QRD	OleP in complex with testosterone in high salt crystallization conditions 分子名称: Cytochrome P-450, FORMIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Fata, F, Costanzo, A, Freda, I, Gugole, E, Bulfaro, G, Barbizzi, L, Di Renzo, M, Savino, C, Vallone, B, Montemiglio, L.C. 登録日 2023-10-06 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 OleP in complex with testosterone in high salt crystallization conditions To Be Published
8QYI	OleP in complex with lithocholic acid in high salt crystallization conditions 分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, Cytochrome P-450, FORMIC ACID, ... 著者 Fata, F, Costanzo, A, Freda, I, Gugole, E, Bulfaro, G, Barbizzi, L, Di Renzo, M, Savino, C, Vallone, B, Montemiglio, L.C. 登録日 2023-10-26 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 OleP in complex with lithocolic acid in high salt crystallization conditions To Be Published
8Q6X	Crystal structure of Cytochrome P450 GymB5 from Streptomyces katrae 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Freytag, J, Mueller, J.M, Stehle, T, Zocher, G. 登録日 2023-08-15 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Intramolecular Coupling and Nucleobase Transfer - How Cytochrome P450 Enzymes GymBx Establish Their Chemoselectivity Chemcatchem, 16, 2024
8Q6Y	Crystal structure of Cytochrome P450 GymB5 from Streptomyces katrae in complex with cYY and Hypoxanthine 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, 1,2-ETHANEDIOL, Cytochrome P450, ... 著者 Freytag, J, Mueller, J.M, Stehle, T, Zocher, G. 登録日 2023-08-15 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Intramolecular Coupling and Nucleobase Transfer - How Cytochrome P450 Enzymes GymBx Establish Their Chemoselectivity Chemcatchem, 16, 2024
8VX0	CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN 分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ... 著者 Shah, M.B. 登録日 2024-02-02 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
8VZ7	Crystal Structure of Human Cytochrome P450 2C9*27 (R150L) Genetic Variant in Complex with the Drug Losartan 分子名称: Cytochrome P450 2C9, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Shah, M.B. 登録日 2024-02-11 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan. J.Inorg.Biochem., 258, 2024
8VL0	The crystal structure of wild-type CYP199A4 bound to 4-(2-oxopropyl)benzoic acid 分子名称: 4-(2-oxopropyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2024-01-11 公開日 2024-05-08 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.837 Å) 主引用文献 Selective alpha-Hydroxyketone Formation and Subsequent C-C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes Acs Catalysis, 14, 2024
8VKF	The crystal structure of wild-type CYP199A4 bound to 4-propionylbenzoic acid 分子名称: 4-propanoylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2024-01-09 公開日 2024-05-08 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Selective alpha-Hydroxyketone Formation and Subsequent C-C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes Acs Catalysis, 14, 2024
8VFR	The crystal structure of 4-methylbenzoic acid-bound GALQE CYP199A4 after soaking in 10 mM H2O2 for 5 minutes 分子名称: 4-(hydroxymethyl)benzoic acid, 4-METHYLBENZOIC ACID, CHLORIDE ION, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-12-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.018 Å) 主引用文献 Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region Acs Catalysis, 2024
8VF3	The crystal structure of GALQE CYP199A4 bound to 4-methoxybenzoic acid 分子名称: 4-METHOXYBENZOIC ACID, ACETATE ION, CHLORIDE ION, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-12-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.469 Å) 主引用文献 Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region Acs Catalysis, 2024
8VF0	The crystal structure of QE CYP199A4 bound to 4-methoxybenzoic acid 分子名称: 4-METHOXYBENZOIC ACID, CHLORIDE ION, Cytochrome P450 enzyme (CYP199A4), ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-12-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.028 Å) 主引用文献 Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region Acs Catalysis, 2024
8VFP	The crystal structure of GALQE CYP199A4 bound to 4-methylbenzoic acid 分子名称: 4-METHYLBENZOIC ACID, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Podgorski, M.N, Bell, S.G. 登録日 2023-12-21 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Engineering Peroxygenase Activity into Cytochrome P450 Monooxygenases through Modification of the Oxygen Binding Region Acs Catalysis, 2024
8JRL	Crystal structure of P450 TleB with an indole alkaloid 分子名称: (2~{S})-~{N}-[(2~{S})-1-(4-fluoranyl-1~{H}-indol-3-yl)-3-oxidanyl-propan-2-yl]-3-methyl-2-sulfanyl-butanamide, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, J, Yan, W.P. 登録日 2023-06-17 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Regulation of P450 TleB catalytic flow for the synthesis of sulfur-containing indole alkaloids by substrate structure-directed strategy. and protein engineering. Sci China Chem, 66, 2023
8Q5J	Cytochrome P450 monooxygenase from Streptomyces scabiei (SscaCYP) 分子名称: Cytochrome P450 107B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Opperman, D.J, Ebrecht, A.C. 登録日 2023-08-09 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Natural alternative heme-environments allow efficient peroxygenase activity by cytochrome P450 monooxygenases Catalysis Science And Technology, 13, 2023
8QZE	Heme-domain BM3 variant 21B3_F87V-A328F 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, IMIDAZOLE, ... 著者 Opperman, D.J, Ebrecht, A.C, Aschenbrenner, J.C. 登録日 2023-10-27 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Mol Catal, 557, 2024
8QZF	Heme-domain BM3 mutant T268E 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, DI(HYDROXYETHYL)ETHER, ... 著者 Opperman, D.J, Ebrecht, A.C, Aschenbrenner, J.C. 登録日 2023-10-27 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Revisiting strategies and their combinatorial effect for introducing peroxygenase activity in CYP102A1 (P450BM3) Mol Catal, 557, 2024
8SWL	Substrate free structure of cytochrome P450 CYP105Q4 from mycobacterium marinum 分子名称: Cytochrome P450 105Q4 Cyp105Q4, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL 著者 Mohamed, H.A, Bruning, J.B, Bell, S.G. 登録日 2023-05-19 公開日 2024-03-27 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum. Arch.Biochem.Biophys., 754, 2024
8CKN	Cytochrome P450 CYP143A1 (Rv1785c) from Mycobacterium tuberculosis 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Selvam, I.R. 登録日 2023-02-16 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 1.54 Angstrom structure of cytochrome P450 CYP143A1 (Rv1785c) from Mycobacterium tuberculosis To Be Published

 

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