8X3E

CYP725A4-Taxa-4,11-diene complex

This is a non-PDB format compatible entry.

Summary for 8X3E

• Entry DOI: 10.2210/pdb8x3e/pdb
• Descriptor: Taxadiene 5-alpha hydroxylase, (1~{R},3~{R},8~{R})-4,8,12,15,15-pentamethyltricyclo[9.3.1.0^{3,8}]pentadeca-4,11-diene, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• Functional Keywords: complex, biosynthetic protein
• Biological source: Taxus cuspidata
• Total number of polymer chains: 1
• Total formula weight: 49284.56

Authors

Chang, Z.,Wang, Q. (deposition date: 2023-11-13, release date: 2024-08-14)

• Primary citation: Song, X.,Wang, Q.,Zhu, X.,Fang, W.,Liu, X.,Shi, C.,Chang, Z.,Jiang, H.,Wang, B.; Unraveling the Catalytic Mechanism of Taxadiene-5alpha-hydroxylase from Crystallography and Computational Analyses.; Acs Catalysis, 14:3912-3925, 2024; DOI: 10.1021/acscatal.3c05807

Experimental method

X-RAY DIFFRACTION (2.5 Å)