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8S9P
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1:1:1 agrin/LRP4/MuSK complex
分子名称: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
著者Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
登録日2023-03-29
公開日2023-05-17
最終更新日2023-06-14
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
7QE9
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE8
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7E50
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Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
分子名称: AAEL006007-PA, GLYCEROL, Plasminogen, ...
著者Varsha, A.W, Jobichen, C, Mok, Y.K.
登録日2021-02-16
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
6KBR
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Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
分子名称: GLYCEROL, K41043, Kallikrein-4
著者Kawaguchi, Y, Nishimiya, D.
登録日2019-06-26
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
5YHN
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Solution structure of the LEKTI Domain 4
分子名称: cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5
著者Mok, Y.K, Ramesh, K.
登録日2017-09-29
公開日2018-08-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity.
Structure, 26, 2018
5DAE
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Kazal type inhibitor from salivary glands of Aedes aegypti mosquito
分子名称: AAEL006007-PA
著者Torquato, R.J.S, Pereira, P.J.B, Tanaka, A.S.
登録日2015-08-19
公開日2016-09-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4OVO
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REFINED X-RAY CRYSTAL STRUCTURES OF THE REACTIVE SITE MODIFIED OVOMUCOID INHIBITOR THIRD DOMAINS FROM SILVER PHEASANT (OMSVP3(ASTERISK)) AND FROM JAPANESE QUAIL (OMJPQ3(ASTERISK))
分子名称: OVOMUCOID THIRD DOMAIN CLEAVED RDI
著者Musil, D, Bode, W.
登録日1991-05-13
公開日1993-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*).
J.Mol.Biol., 220, 1991
4HGU
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Crystal Structure of Galleria mellonella Silk Protease Inhibitor 2
分子名称: SODIUM ION, Silk protease inhibitor 2
著者Krzywda, S, Jaskolski, M, Dvornyk, A, Kludkiewicz, B, Grzelak, K, Zagorski, W, Bal, W, Kopera, E.
登録日2012-10-08
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
3SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
3SGB
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STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
分子名称: PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3)
著者Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G.
登録日1983-01-21
公開日1983-07-12
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
3OVO
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REFINED X-RAY CRYSTAL STRUCTURES OF THE REACTIVE SITE MODIFIED OVOMUCOID INHIBITOR THIRD DOMAINS FROM SILVER PHEASANT (OMSVP3(ASTERISK)) AND FROM JAPANESE QUAIL (OMJPQ3(ASTERISK))
分子名称: OVOMUCOID THIRD DOMAIN CLEAVED RDI
著者Musil, D, Bode, W.
登録日1991-05-13
公開日1993-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*).
J.Mol.Biol., 220, 1991
2V53
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Crystal structure of a SPARC-collagen complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN, ...
著者Hohenester, E, Sasaki, T, Giudici, C, Farndale, R.W, Bachinger, H.P.
登録日2008-10-01
公開日2008-11-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Sequence-Specific Collagen Recognition by Sparc.
Proc.Natl.Acad.Sci.USA, 105, 2008
2SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2SGP
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PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: OVOMUCOID INHIBITOR, PHOSPHATE ION, PROTEINASE B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2001-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2SGF
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PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
2SGE
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GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
Protein Sci., 4, 1995
2SGD
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ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
2OVO
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THE CRYSTAL AND MOLECULAR STRUCTURE OF THE THIRD DOMAIN OF SILVER PHEASANT OVOMUCOID (OMSVP3)
分子名称: OVOMUCOID THIRD DOMAIN
著者Bode, W, Epp, O.
登録日1985-06-11
公開日1985-11-08
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal and molecular structure of the third domain of silver pheasant ovomucoid (OMSVP3).
Eur.J.Biochem., 147, 1985
2NU4
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Proteinase B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU3
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Proteinase B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU2
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Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
分子名称: Ovomucoid, Streptogrisin B, Protease B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
To be Published
2NU1
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Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
分子名称: Ovomucoid, Streptogrisin B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I and Tyr18I
To be Published
2NU0
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Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
分子名称: Ovomucoid, Streptogrisin B, Protease B
著者Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G.
登録日2006-11-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular structures of the complexes of SGPB with OMTKY3 aromatic P1 variants Trp18I, His18I, Phe18I, and Tyr18I
To be Published
2N71
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NMR structure of CmPI-II, a serin protease inhibitor isolated from mollusk Cenchitis muricatus
分子名称: Protease inhibitor 2
著者Cabrera-Munoz, A, Rojas, L, Alonso del Rivero Antigua, M, Pires, J.
登録日2015-09-01
公開日2016-09-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR structure of CmPI-II, a non-classical Kazal protease inhibitor: Understanding its conformational dynamics and subtilisin A inhibition.
J.Struct.Biol., 206, 2019

 

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