PDB: 446 件ウェブページステータス検索Chemie searchBIRD

---

5KH8	Solution structures of the apo state fluoride riboswitch 分子名称: riboswitch (47-MER) 著者 Zhang, Q, Zhao, B. 登録日 2016-06-14 公開日 2017-07-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An excited state underlies gene regulation of a transcriptional riboswitch. Nat. Chem. Biol., 13, 2017
3IVN	Structure of the U65C mutant A-riboswitch aptamer from the Bacillus subtilis pbuE operon 分子名称: A-riboswitch, BROMIDE ION, MAGNESIUM ION 著者 Delfosse, V, Dagenais, P, Chausse, D, Di Tomasso, G, Legault, P. 登録日 2009-09-01 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Riboswitch structure: an internal residue mimicking the purine ligand. Nucleic Acids Res., 38, 2010
3SUY	Crystal structure of THF riboswitch, unbound status 分子名称: riboswitch 著者 Huang, L, Serganov, A, Patel, D.J. 登録日 2011-07-11 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Long-range pseudoknot interactions dictate the regulatory response in the tetrahydrofolate riboswitch. Proc.Natl.Acad.Sci.USA, 108, 2011
5SWD	Structure of the adenine riboswitch aptamer domain in an intermediate-bound state 分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ... 著者 Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. 登録日 2016-08-08 公開日 2016-11-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
5SWE	Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography 分子名称: ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain 著者 Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. 登録日 2016-08-08 公開日 2016-11-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
6WZS	Fusibacterium ulcerans ZTP riboswitch bound to m-1-pyridinyl AICA 分子名称: 5-amino-1-(pyridin-3-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ... 著者 Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B. 登録日 2020-05-14 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.23 Å) 主引用文献 Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design. Cell Chem Biol, 27, 2020
6WZR	Fusibacterium ulcerans ZTP riboswitch bound to p-1-pyridinyl AICA 分子名称: 5-amino-1-(pyridin-4-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ... 著者 Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B. 登録日 2020-05-14 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design. Cell Chem Biol, 27, 2020
4FE5	Crystal structure of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine 分子名称: ACETATE ION, COBALT HEXAMMINE(III), HYPOXANTHINE, ... 著者 Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. 登録日 2012-05-29 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature, 432, 2004
8FZA	Class I type III preQ1 riboswitch from E. coli 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, MANGANESE (II) ION, PreQ1 Riboswitch (30-MER) 著者 Wedekind, J.E, Schroeder, G.M, Jenkins, J.L. 登録日 2023-01-27 公開日 2023-08-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and function analysis of a type III preQ 1 -I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence. J.Biol.Chem., 299, 2023
5E54	Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser 分子名称: MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain 著者 Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. 登録日 2015-10-07 公開日 2016-11-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Nature, 541, 2017
8FB3	PreQ1-1 (type-1) riboswitch with stacked metabolites and a C10-G34 base pair in the expression platform 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, MAGNESIUM ION, RNA (34-MER) Riboswitch 著者 Wedekind, J.E, Schroeder, G.M, Jenkins, J.L. 登録日 2022-11-29 公開日 2023-02-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A riboswitch separated from its ribosome-binding site still regulates translation. Nucleic Acids Res., 51, 2023
6UC8	Guanine riboswitch bound to 8-aminoguanine 分子名称: 8-AMINOGUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Matyjasik, M.M, Hall, S.D, Batey, R.T. 登録日 2019-09-15 公開日 2020-07-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
8GXB	Crystal structure of NAD+ -II riboswitch in complex with NAD+ 分子名称: MAGNESIUM ION, NAD+ II riboswitch, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Xu, X.C, Ren, A.M. 登録日 2022-09-19 公開日 2023-01-18 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-based investigations of the NAD+-II riboswitch. Nucleic Acids Res., 51, 2023
6UC9	Guanine riboswitch bound to O6-cyclohexylmethyl guanine 分子名称: 6-O-CYCLOHEXYLMETHYL GUANINE, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Matyjasik, M.M, Batey, R.T. 登録日 2019-09-15 公開日 2020-07-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020
3IQR	SAM-I riboswitch from T. tencongensis variant A94G bound with SAM 分子名称: BARIUM ION, S-ADENOSYLMETHIONINE, SAM-I riboswitch 著者 Montange, R.K, Batey, R.T. 登録日 2009-08-20 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Free state conformational sampling of the SAM-I riboswitch aptamer domain. Structure, 18, 2010
3IQN	Free-state structural transitions of the SAM-I riboswitch 分子名称: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ... 著者 Montange, R.K, Batey, R.T. 登録日 2009-08-20 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Free state conformational sampling of the SAM-I riboswitch aptamer domain. Structure, 18, 2010
3IQP	SAM-I riboswitch from T. tencongensis variant A94G apo form 分子名称: BARIUM ION, SAM-I riboswitch 著者 Montange, R.K, Batey, R.T. 登録日 2009-08-20 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Free state conformational sampling of the SAM-I riboswitch aptamer domain. Structure, 18, 2010
3Q51	Structural analysis of a class I PreQ1 riboswitch aptamer in the metabolite-free state. 分子名称: MAGNESIUM ION, PREQ1 RIBOSWITCH, SULFATE ION 著者 Wedekind, J.E, Jenkins, J.L, Krucinska, J. 登録日 2010-12-26 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation. J.Biol.Chem., 286, 2011
3Q50	Structural analysis of a class I PreQ1 riboswitch aptamer in the metabolite-bound state 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, PREQ1 RIBOSWITCH, SULFATE ION 著者 Jenkins, J.L, Krucinska, J, Wedekind, J.E. 登録日 2010-12-26 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation. J.Biol.Chem., 286, 2011
5NWQ	The structure of the thermobifida fusca guanidine III riboswitch with guanidine. 分子名称: GUANIDINE, Guanidine III riboswitch, MAGNESIUM ION, ... 著者 Huang, L, Wang, J, Lilley, D.M.J. 登録日 2017-05-08 公開日 2017-10-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure of the Guanidine III Riboswitch. Cell Chem Biol, 24, 2017
5NZD	The structure of the thermobifida fusca guanidine III riboswitch in space group P212121. 分子名称: ACETATE ION, MAGNESIUM ION, SODIUM ION, ... 著者 Huang, L, Wang, J, Lilley, D.M.J. 登録日 2017-05-13 公開日 2017-10-18 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.007 Å) 主引用文献 Structure of the Guanidine III Riboswitch. Cell Chem Biol, 24, 2017
3GCA	The structural basis for recognition of the preQ0 metabolite by an unusually small riboswitch aptamer domain 分子名称: 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, PreQ1 riboswitch, SULFATE ION 著者 Spitale, R.C, Wedekind, J.E. 登録日 2009-02-21 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain. J.Biol.Chem., 284, 2009
3K1V	Cocrystal structure of a mutant class-I preQ1 riboswitch 分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, CALCIUM ION, PreQ1 riboswitch 著者 Klein, D.J, Edwards, T.E, Ferre-D'Amare, A.R. 登録日 2009-09-28 公開日 2009-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cocrystal Structure of a Class I Preq1 Riboswitch Reveals a Pseudoknot Recognizing an Essential Hypermodified Nucleobase Nat.Struct.Mol.Biol., 16, 2009
2GDI	Crystal structure of thiamine pyrophosphate-specific riboswitch in complex with thiamine pyrophosphate 分子名称: MAGNESIUM ION, POTASSIUM ION, SODIUM ION, ... 著者 Serganov, A. 登録日 2006-03-16 公開日 2006-07-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature, 441, 2006
6UC7	Structure of guanine riboswitch bound to N2-acetyl guanine 分子名称: COBALT HEXAMMINE(III), N-(6-oxo-6,9-dihydro-3H-purin-2-yl)acetamide, guanine riboswitch 著者 Matyjasik, M.M, Batey, R.T. 登録日 2019-09-15 公開日 2020-07-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules, 25, 2020

 

12345678910111213141516>