2HJK
| Crystal Structure of HLA-B5703 and HIV-1 peptide | 分子名称: | Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57 | 著者 | Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A. | 登録日 | 2006-06-30 | 公開日 | 2006-10-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection. J.Immunol., 177, 2006
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2DDB
| Crystal structure of pseudecin from Pseudechis porphyriacus | 分子名称: | FORMIC ACID, GLYCEROL, Pseudecin, ... | 著者 | Suzuki, N, Yamazaki, Y, Fujimoto, Z, Morita, T, Mizuno, H. | 登録日 | 2006-01-25 | 公開日 | 2007-01-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain Acta Crystallogr.,Sect.D, 64, 2008
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6MDS
| Crystal structure of Streptococcus pyogenes endo-beta-N-acetylglucosaminidase (EndoS2) with complex biantennary glycan | 分子名称: | CALCIUM ION, Endo-beta-N-acetylglucosaminidase, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Klontz, E.H, Trastoy, B, Orwenyo, J, Wang, L.X, Guerin, M.E, Sundberg, E.J. | 登録日 | 2018-09-05 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Basis of Broad SpectrumN-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2. ACS Cent Sci, 5, 2019
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2HJF
| Potassium channel kcsa-fab complex with tetrabutylammonium (TBA) | 分子名称: | Antibody fragment Heavy chain, Antibody fragment Light chain, POTASSIUM ION, ... | 著者 | Faraldo-Gomez, J.D, Kutluay, E, Jogini, V, Zhao, Y, Heginbotham, L, Roux, B. | 登録日 | 2006-06-30 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol., 365, 2007
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6S3R
| Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. | 分子名称: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | 著者 | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | 登録日 | 2019-06-25 | 公開日 | 2020-03-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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2HFP
| Crystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands | 分子名称: | 3-(4-METHOXYPHENYL)-N-(PHENYLSULFONYL)-1-[3-(TRIFLUOROMETHYL)BENZYL]-1H-INDOLE-2-CARBOXAMIDE, Peroxisome proliferator-activated receptor gamma, SRC Peptide Fragment | 著者 | Pokross, M.E, Evdokimov, A.G, Walter, R.L, Mekel, M.J, Hopkins, C.R. | 登録日 | 2006-06-25 | 公開日 | 2006-09-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis. Bioorg.Med.Chem.Lett., 16, 2006
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2DDF
| Crystal structure of TACE in complex with TAPI-2 | 分子名称: | ADAM 17, CALCIUM ION, CITRIC ACID, ... | 著者 | Orth, P. | 登録日 | 2006-01-28 | 公開日 | 2006-03-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Stabilization of the autoproteolysis of TNF-alpha converting enzyme (TACE) results in a novel crystal form suitable for structure-based drug design studies. Protein Eng.Des.Sel., 19, 2006
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2HSG
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6RLP
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2ICE
| CRIg bound to C3c | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C3 alpha chain, ... | 著者 | Wiesmann, C. | 登録日 | 2006-09-12 | 公開日 | 2006-11-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature, 444, 2006
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2ID0
| Escherichia coli RNase II | 分子名称: | Exoribonuclease 2, MANGANESE (II) ION | 著者 | Zuo, Y, Zhang, J, Wang, Y, Malhotra, A. | 登録日 | 2006-09-13 | 公開日 | 2006-10-03 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for Processivity and Single-Strand Specificity of RNase II. Mol.Cell, 24, 2006
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6SCN
| 33mer structure of the Salmonella flagella MS-ring protein FliF | 分子名称: | Flagellar M-ring protein | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | 登録日 | 2019-07-24 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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2IIF
| single chain Integration Host Factor mutant protein (scIHF2-K45aE) in complex with DNA | 分子名称: | DNA (5'-D(*DGP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DAP*DAP*DGP*DCP*DAP*DTP*DT)-3'), Integration host factor, ... | 著者 | Bao, Q, Droege, P, Davey, C.A. | 登録日 | 2006-09-28 | 公開日 | 2007-02-20 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending J.Mol.Biol., 367, 2007
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2IIV
| Human dipeptidyl peptidase 4 in complex with a diazepan-2-one inhibitor | 分子名称: | (3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Weber, A.E, Biftu, T. | 登録日 | 2006-09-28 | 公開日 | 2006-11-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | (3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Bioorg.Med.Chem.Lett., 17, 2007
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7B5E
| Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution | 分子名称: | Anoctamin-1, CALCIUM ION | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | 登録日 | 2020-12-03 | 公開日 | 2021-02-10 | 最終更新日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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7B5D
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7B5C
| Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution | 分子名称: | Anoctamin-1, CALCIUM ION | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | 登録日 | 2020-12-03 | 公開日 | 2021-02-10 | 最終更新日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A. Nat Commun, 12, 2021
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6XZP
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | 登録日 | 2020-02-05 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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2ICI
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2ICW
| Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | 著者 | Wang, L, Zhao, Y, Li, H. | 登録日 | 2006-09-13 | 公開日 | 2007-03-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC. Nat.Struct.Mol.Biol., 14, 2007
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2IHY
| Structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter | 分子名称: | ABC transporter, ATP-binding protein, SULFATE ION | 著者 | McGrath, T.E, Yu, C.S, Romanov, V, Lam, R, Dharamsi, A, Virag, C, Mansoury, K, Thambipillai, D, Richards, D, Guthrie, J, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2006-09-27 | 公開日 | 2007-09-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter To be Published
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6SD3
| 34mer structure of the Salmonella flagella MS-ring protein FliF | 分子名称: | Flagellar M-ring protein | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | 登録日 | 2019-07-26 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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6SD2
| Structure of the RBM2inner region of the Salmonella flagella MS-ring protein FliF with 21-fold symmetry applied. | 分子名称: | Flagellar M-ring protein | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | 登録日 | 2019-07-26 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
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7AGX
| Apo-state type 3 secretion system export apparatus complex from Salmonella enterica typhimurium | 分子名称: | Protein PrgI, Protein PrgJ, Surface presentation of antigens protein SpaP, ... | 著者 | Goessweiner-Mohr, N, Fahrenkamp, D, Miletic, S, Wald, J, Marlovits, T. | 登録日 | 2020-09-23 | 公開日 | 2021-03-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation. Nat Commun, 12, 2021
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2IH1
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | 著者 | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | 登録日 | 2006-09-25 | 公開日 | 2006-11-21 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
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