6XJT
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![BU of 6xjt by Molmil](/molmil-images/mine/6xjt) | Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ) | 分子名称: | (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... | 著者 | Baumhardt, J.M, Chook, Y.M. | 登録日 | 2020-06-24 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | 主引用文献 | Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
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8RDR
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![BU of 8rdr by Molmil](/molmil-images/mine/8rdr) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8g | 分子名称: | (5~{S})-3-(2-nitrophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Bischof, L, Hartmann, M.D. | 登録日 | 2023-12-08 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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8QLE
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![BU of 8qle by Molmil](/molmil-images/mine/8qle) | Crystal structure of the light-driven sodium pump ErNaR in the monomeric form at pH 4.6 | 分子名称: | Bacteriorhodopsin-like protein, EICOSANE, OLEIC ACID | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Astashkin, R, Bourenkov, G. | 登録日 | 2023-09-19 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion. Nat Commun, 15, 2024
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8RKS
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![BU of 8rks by Molmil](/molmil-images/mine/8rks) | Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | 著者 | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | 登録日 | 2023-12-30 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21. Protein Sci., 33, 2024
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8QDB
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![BU of 8qdb by Molmil](/molmil-images/mine/8qdb) | Wdyg1p Ser256DHA (PSF) | 分子名称: | 1,2-ETHANEDIOL, Yellowish-green 1-like protein | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8RDS
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![BU of 8rds by Molmil](/molmil-images/mine/8rds) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8i | 分子名称: | (5~{S})-3-(2-methoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Bischof, L, Hartmann, M.D. | 登録日 | 2023-12-08 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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8RDT
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![BU of 8rdt by Molmil](/molmil-images/mine/8rdt) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8j | 分子名称: | (5~{S})-3-(2,3,4-trimethoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Bischof, L, Hartmann, M.D. | 登録日 | 2023-12-08 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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8QAV
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![BU of 8qav by Molmil](/molmil-images/mine/8qav) | Medicago truncatula HISN5 (IGPD) in complex with MN and IG2 | 分子名称: | (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION | 著者 | Witek, W, Ruszkowski, M. | 登録日 | 2023-08-23 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
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8RGQ
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![BU of 8rgq by Molmil](/molmil-images/mine/8rgq) | Open Complex I from murine liver | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Vercellino, I, Sazanov, L.A. | 登録日 | 2023-12-14 | 公開日 | 2024-04-24 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 31, 2024
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8QWR
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![BU of 8qwr by Molmil](/molmil-images/mine/8qwr) | Crystal structure of CotB2 variant V80L | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Cyclooctat-9-en-7-ol synthase, ... | 著者 | Dimos, N, Himpich, S, Ringel, M, Driller, R, Major, D.T, Brueck, T, Loll, B. | 登録日 | 2023-10-20 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of CotB2 variant V80L To Be Published
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8QD8
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![BU of 8qd8 by Molmil](/molmil-images/mine/8qd8) | Wdyg1p in complex with 1,3-Dihydroxynaphthalene | 分子名称: | 1,2-ETHANEDIOL, Yellowish-green 1-like protein, naphthalene-1,3-diol | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8QD2
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![BU of 8qd2 by Molmil](/molmil-images/mine/8qd2) | Ayg1p in complex with 1,3-Dihydroxynaphthalene | 分子名称: | Pigment biosynthesis protein yellowish-green 1, naphthalene-1,3-diol | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8RDQ
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![BU of 8rdq by Molmil](/molmil-images/mine/8rdq) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8b | 分子名称: | (5S)-3-(2,4-dichlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Bischof, L, Hartmann, M.D. | 登録日 | 2023-12-08 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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1ABW
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![BU of 1abw by Molmil](/molmil-images/mine/1abw) | DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN) | 分子名称: | HEMOGLOBIN-BASED BLOOD SUBSTITUTE, LEUCINE, METHIONINE, ... | 著者 | Kundrot, C.E, Kroeger, K.S. | 登録日 | 1997-01-29 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of a hemoglobin-based blood substitute: insights into the function of allosteric proteins. Structure, 5, 1997
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8QLF
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![BU of 8qlf by Molmil](/molmil-images/mine/8qlf) | Crystal structure of the light-driven sodium pump ErNaR in the monomeric form at pH 8.8 | 分子名称: | Bacteriorhodopsin-like protein, EICOSANE, OLEIC ACID | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Astashkin, R, Bourenkov, G. | 登録日 | 2023-09-19 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion. Nat Commun, 15, 2024
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8RCW
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![BU of 8rcw by Molmil](/molmil-images/mine/8rcw) | Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the lead compound SMARt751 | 分子名称: | 4,4,4-tris(fluoranyl)-1-[4-(4-fluorophenyl)piperidin-1-yl]butan-1-one, HTH-type transcriptional regulator VirS | 著者 | Grosse, C, Sigoillot, M, Megalizzi, V, Tanina, A, Willand, N, Baulard, A.R, Wintjens, R. | 登録日 | 2023-12-07 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis VirS regulator reveals its interaction with the lead compound SMARt751. J.Struct.Biol., 216, 2024
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8QQZ
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![BU of 8qqz by Molmil](/molmil-images/mine/8qqz) | Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 8.0 | 分子名称: | Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A. | 登録日 | 2023-10-06 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion. Nat Commun, 15, 2024
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8RDP
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![BU of 8rdp by Molmil](/molmil-images/mine/8rdp) | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8a | 分子名称: | (5~{S})-3-(2-chlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | 著者 | Bischof, L, Hartmann, M.D. | 登録日 | 2023-12-08 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode. Eur.J.Med.Chem., 270, 2024
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8QR0
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![BU of 8qr0 by Molmil](/molmil-images/mine/8qr0) | Cryo-EM structure of the light-driven sodium pump ErNaR in the pentameric form at pH 4.3 | 分子名称: | Bacteriorhodopsin-like protein, DODECYL-BETA-D-MALTOSIDE, EICOSANE | 著者 | Kovalev, K, Podoliak, E, Lamm, G.H.U, Marin, E, Stetsenko, A, Guskov, A. | 登録日 | 2023-10-06 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion. Nat Commun, 15, 2024
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8QAY
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![BU of 8qay by Molmil](/molmil-images/mine/8qay) | Medicago truncatula HISN5 (IGPD) in complex with MN, FMT, ACT, CIT, EDO, SO4 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CITRIC ACID, ... | 著者 | Witek, W, Ruszkowski, M. | 登録日 | 2023-08-23 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
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8R33
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![BU of 8r33 by Molmil](/molmil-images/mine/8r33) | |
8RP3
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![BU of 8rp3 by Molmil](/molmil-images/mine/8rp3) | |
8QD6
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![BU of 8qd6 by Molmil](/molmil-images/mine/8qd6) | AntI Ser245DHA (PMSF) | 分子名称: | ACETATE ION, Photorhabdus luminescens subsp. laumondii TTO1 complete genome segment 15/17, SODIUM ION, ... | 著者 | Schmalhofer, M, Vagstad, A.L, Zhou, Q, Bode, H.B, Groll, M. | 登録日 | 2023-08-28 | 公開日 | 2024-03-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Polyketide Trimming Shapes Dihydroxynaphthalene-Melanin and Anthraquinone Pigments. Adv Sci, 11, 2024
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8RP5
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![BU of 8rp5 by Molmil](/molmil-images/mine/8rp5) | Alpha-Methylacyl-CoA racemase from Mycobacterium tuberculosis (E241A mutant) | 分子名称: | 1,2-ETHANEDIOL, Alpha-methylacyl-CoA racemase, TRIETHYLENE GLYCOL | 著者 | Mojanaga, O.O, Acharya, K.R, Lloyd, M.D. | 登録日 | 2024-01-12 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | alpha-Methylacyl-CoA Racemase from Mycobacterium tuberculosis -Detailed Kinetic and Structural Characterization of the Active Site. Biomolecules, 14, 2024
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1A2A
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![BU of 1a2a by Molmil](/molmil-images/mine/1a2a) | AGKISTROTOXIN, A PHOSPHOLIPASE A2-TYPE PRESYNAPTIC NEUROTOXIN FROM AGKISTRODON HALYS PALLAS | 分子名称: | CHLORIDE ION, PHOSPHOLIPASE A2 | 著者 | Tang, L, Zhou, Y, Lin, Z. | 登録日 | 1997-12-25 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas. J.Mol.Biol., 282, 1998
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