PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

---

4X51	X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y 分子名称: Interleukin-10 著者 Kuenze, G. 登録日 2014-12-04 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y To Be Published
5US3	Heterogeneous-backbone Foldamer Mimic of the Sp1-3 Zinc Finger 分子名称: Heterogeneous-Backbone Variant of the Sp1-3 Zinc Finger: N-Me-Ala3, N-Me-Arg10, beta-3-Asp15, ... 著者 George, K.L, Horne, W.S. 登録日 2017-02-13 公開日 2017-05-31 最終更新日 2024-07-10 実験手法 SOLUTION NMR 主引用文献 Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure. J. Am. Chem. Soc., 139, 2017
6BH0	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (R)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N51) 分子名称: 2-{(R)-(2-chlorophenyl)[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, Lysine-specific demethylase 5A, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-10-29 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.985 Å) 主引用文献 Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
4X6H	Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors. 分子名称: 4-amino-3-fluoro-N-(1-{[(2Z)-2-iminoethyl]carbamoyl}cyclohexyl)benzamide, 4-amino-N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-3-fluorobenzamide, Cathepsin K, ... 著者 Borisek, J, Mohar, B, Vizovisek, M, Sosnowski, P, Turk, D, Turk, B, Novic, M. 登録日 2014-12-08 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors. J.Med.Chem., 58, 2015
4X8D	Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine 分子名称: CALCIUM ION, CHLORIDE ION, GAMMA-GLUTAMYLCYSTEINE, ... 著者 Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. 登録日 2014-12-10 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
4WL2	Structure of penicillin V acylase from Pectobacterium atrosepticum 分子名称: Putative exported choloylglycine hydrolase 著者 Ramasamy, S, Avinash, V.S, Pundle, A.V, Suresh, C.G. 登録日 2014-10-06 公開日 2015-10-07 最終更新日 2016-04-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural analysis of a penicillin V acylase from Pectobacterium atrosepticum confirms the importance of two Trp residues for activity and specificity J.Struct.Biol., 193, 2016
5V4C	Peptide 38136 modified from fragment 21-37 of Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) 分子名称: Peptide 38136 著者 Bermudez, A, Patarroyo, M.E. 登録日 2017-03-09 公開日 2018-08-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Peptide 38136 modified from fragment 21-37 of Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) To Be Published
5VD1	CRYSTAL STRUCTURE OF HUMAN MYT1 KINASE DOMAIN IN COMPLEX WITH PHA-848125 分子名称: DI(HYDROXYETHYL)ETHER, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, N,1,4,4-TETRAMETHYL-8-{[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]AMINO}-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE 著者 Zhu, J.-Y, Schonbrunn, E. 登録日 2017-04-01 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
4WKA	Crystal structure of human chitotriosidase-1 catalytic domain at 0.95 A resolution 分子名称: Chitotriosidase-1, L(+)-TARTARIC ACID 著者 Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A. 登録日 2014-10-02 公開日 2015-07-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM. Acta Crystallogr.,Sect.D, 71, 2015
5VFB	1.36 Angstrom Resolution Crystal Structure of Malate Synthase G from Pseudomonas aeruginosa in Complex with Glycolic Acid. 分子名称: CHLORIDE ION, GLYCOLIC ACID, Malate synthase G, ... 著者 Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-04-07 公開日 2017-04-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 1.36 Angstrom Resolution Crystal Structure of Malate Synthase G from Pseudomonas aeruginosa in Complex with Glycolic Acid. To Be Published
6BMZ	Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor 分子名称: (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, CHLORIDE ION, Matrix protein 2 著者 Thomaston, J.L, DeGrado, W.F. 登録日 2017-11-15 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters. J. Am. Chem. Soc., 140, 2018
4WL0	Ligand-free structure of human platelet phosphofructokinase in an R-state, crystal form I 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION 著者 Kloos, M, Strater, N. 登録日 2014-10-05 公開日 2015-06-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
6BNI	Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and Adenosine 分子名称: 1,2-ETHANEDIOL, ADENOSINE, LYSINE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-11-16 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and Adenosine to be published
6BGZ	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(1-methyl-1H-imidazol-2-yl)ethoxy)methyl)-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N47) 分子名称: 2-{(S)-(2-chlorophenyl)[2-(1-methyl-1H-imidazol-2-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid, GLYCEROL, Lysine-specific demethylase 5A, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-10-29 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.688 Å) 主引用文献 Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
4WWU	Structure of Mex67:Mtr2 分子名称: ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2 著者 Aibara, S, Valkov, E, Stewart, M. 登録日 2014-11-12 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface. Nucleic Acids Res., 43, 2015
5VKA	Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and N-omega-hydroxy-L-arginine 分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, MANGANESE (II) ION, ... 著者 Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. 登録日 2017-04-21 公開日 2017-08-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.169 Å) 主引用文献 Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist. J. Am. Chem. Soc., 139, 2017
4WZW	Crystal structure of human Puf-A in complex with DNA 分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), Pumilio domain-containing protein KIAA0020 著者 Qiu, C, Hall, T.M.T. 登録日 2014-11-20 公開日 2014-12-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9516 Å) 主引用文献 A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization. Proc.Natl.Acad.Sci.USA, 111, 2014
4X09	Structure of human RNase 6 in complex with sulphate anions 分子名称: GLYCEROL, Ribonuclease K6, SULFATE ION 著者 Prats-Ejarque, G, Arranz-Trullen, J, Blanco, J.A, Pulido, D, Moussaoui, M, Boix, E. 登録日 2014-11-21 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.722 Å) 主引用文献 The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement. Biochem.J., 473, 2016
6BGU	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(propoxy)methyl)-1H-pyrrolo[3,2-b]pyridine (Compound N9) 分子名称: 1,2-ETHANEDIOL, 2-[(R)-(2-chlorophenyl)(propoxy)methyl]-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-10-29 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.684 Å) 主引用文献 Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
6BH2	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR (R)-N-(1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (Compound N54) 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Lysine-specific demethylase 5A, ... 著者 Horton, J.R, Cheng, X. 登録日 2017-10-29 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.447 Å) 主引用文献 Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
4X2C	Clostridium difficile Fic protein_0569 mutant S31A, E35A 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fic family protein putative filamentation induced by cAMP protein, GLYCEROL, ... 著者 Jorgensen, R, Dedic, E. 登録日 2014-11-26 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution To Be Published
5VN6	Crystal structure of Taurine dioxygenase from Burkholderia ambifaria 分子名称: MAGNESIUM ION, Taurine dioxygenase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-04-28 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Taurine dioxygenase from Burkholderia ambifaria TO BE PUBLISHED
5VCZ	CRYSTAL STRUCTURE OF HUMAN MYT1 KINASE DOMAIN IN COMPLEX WITH Bosutinib isomer 分子名称: 1,2-ETHANEDIOL, 4-[(3,5-DICHLORO-4-METHOXYPHENYL)AMINO]-6-METHOXY-7-[3-(4-METHYLPIPERAZIN-1-YL)PROPOXY]QUINOLINE-3-CARBONITRILE, DI(HYDROXYETHYL)ETHER, ... 著者 Zhu, J.-Y, Schonbrunn, E. 登録日 2017-04-01 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
6BHU	Cryo-EM structure of ATP-bound, outward-facing bovine multidrug resistance protein 1 (MRP1) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... 著者 Johnson, Z.L, Chen, J. 登録日 2017-10-31 公開日 2017-12-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1. Cell, 172, 2018
4X4G	RADIATION DAMAGE TO THE NUCLEOPROTEIN COMPLEX C.Esp1396I: DOSE (DWD) 26.8 MGy 分子名称: 35-MER DNA, Regulatory protein 著者 Bury, C.S, McGeehan, J.E, Garman, E.F. 登録日 2014-12-02 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Radiation damage to nucleoprotein complexes in macromolecular crystallography. J.Synchrotron Radiat., 22, 2015

<975976977978979980981982983984985986987988989990>