PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6S5B	Non-square conformation of KtrA R16K mutant ring with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-01 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.052 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
3UZT	Structure of the C13.18 RNA Aptamer in Complex with G Protein-Coupled Receptor Kinase 2 分子名称: Beta-adrenergic receptor kinase 1, C13.18 RNA Aptamer, MAGNESIUM ION 著者 Tesmer, J.J.G, Tesmer, V.M. 登録日 2011-12-07 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Molecular mechanism for inhibition of g protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure, 20, 2012
4HG5	Structural insights into yeast Nit2: wild-type yeast Nit2 in complex with oxaloacetate 分子名称: CACODYLATE ION, GLYCEROL, OXALOACETATE ION, ... 著者 Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. 登録日 2012-10-07 公開日 2013-07-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
6S7R	Non-square conformations of KtrA R16A mutant rings with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-05 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.73 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
1SCY	DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF SCYLLATOXIN BY 1H NUCLEAR MAGNETIC RESONANCE 分子名称: SCYLLATOXIN 著者 Martins, J.C, Van De Ven, F.J.M, Borremans, F.A.M. 登録日 1994-06-02 公開日 1995-01-26 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Determination of the three-dimensional solution structure of scyllatoxin by 1H nuclear magnetic resonance. J.Mol.Biol., 253, 1995
6HHJ	Crystal Structure of AKT1 in Complex with Covalent-Allosteric AKT Inhibitor 24b 分子名称: RAC-alpha serine/threonine-protein kinase, ~{N}-[1-methyl-2-oxidanylidene-3-[1-[[4-(5-oxidanylidene-3-phenyl-6~{H}-1,6-naphthyridin-2-yl)phenyl]methyl]piperidin-4-yl]benzimidazol-5-yl]propanamide 著者 Landel, I, Weisner, J, Mueller, M.P, Scheinpflug, R, Rauh, D. 登録日 2018-08-28 公開日 2019-02-20 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt. Chem Sci, 10, 2019
4HEZ	Activity Enhancers of H64A Variant of Human Carbonic Anhydrase II Possess Multiple Binding Sites within and around the Enzyme Structure 分子名称: 1-METHYLIMIDAZOLE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, R. 登録日 2012-10-04 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3446 Å) 主引用文献 Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles. IUCrJ, 1, 2014
2FVK	Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the substrate dihydrouracil 分子名称: DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, ZINC ION, dihydropyrimidinase 著者 Dobritzsch, D, Lohkamp, B. 登録日 2006-01-31 公開日 2006-03-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity. J.Biol.Chem., 281, 2006
3V3I	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
2G0N	The Crystal Structure of the Human RAC3 in complex with GDP and Chloride 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC) 登録日 2006-02-13 公開日 2006-05-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Crystal Structure of the Human RAC3 in complex with GDP and Chloride To be Published
4GRT	HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, MIXED DISULFIDE BETWEEN TRYPANOTHIONE AND THE ENZYME 分子名称: BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE 著者 Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. 登録日 1997-02-12 公開日 1997-08-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity. Biochemistry, 36, 1997
1A66	SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES 分子名称: CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3') 著者 Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L. 登録日 1998-03-06 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the core NFATC1/DNA complex. Cell(Cambridge,Mass.), 92, 1998
4GR1	THE BINDING OF THE RETRO-ANALOGUE OF GLUTATHIONE DISULFIDE TO GLUTATHIONE REDUCTASE 分子名称: 4N-MALONYL-CYSTEINYL-2,4-DIAMINOBUTYRATE DISULFIDE, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, ... 著者 Schulz, G.E, Janes, W. 登録日 1990-03-26 公開日 1991-10-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The binding of the retro-analogue of glutathione disulfide to glutathione reductase. J.Biol.Chem., 265, 1990
6HED	PAN-proteasome in state 5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.95 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3SQP	Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity 分子名称: 5-methylphenazin-1(5H)-one, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Fritz-Wolf, K, Schirmer, R.H, Koenig, I, Goebel, U. 登録日 2011-07-06 公開日 2011-09-14 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep., 16, 2011
1RZD	X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES 分子名称: CARBONIC ANHYDRASE II, MANGANESE (II) ION, SULFATE ION 著者 Hakansson, K, Wehnert, A, Liljas, A. 登録日 1993-05-25 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray analysis of metal-substituted human carbonic anhydrase II derivatives. Acta Crystallogr.,Sect.D, 50, 1994
4HMY	Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... 著者 Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H. 登録日 2012-10-18 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (7 Å) 主引用文献 Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1. Cell(Cambridge,Mass.), 152, 2013
6VN7	Cryo-EM structure of an activated VIP1 receptor-G protein complex 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Duan, J, Shen, D.-D, Zhou, X.E, Liu, Q.-F, Zhuang, Y.-W, Zhang, H.-B, Xu, P.-Y, Ma, S.-S, He, X.-H, Melcher, K, Zhang, Y, Xu, H.E, Yi, J. 登録日 2020-01-29 公開日 2020-09-02 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy. Nat Commun, 11, 2020
3B1U	Crystal structure of human peptidylarginine deiminase 4 in complex with o-F-amidine 分子名称: 2-{[(2S)-1-amino-5-{[(1Z)-2-fluoroethanimidoyl]amino}-1-oxopentan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Protein-arginine deiminase type-4, ... 著者 Causey, C.P, Jones, J.E, Slack, J.L, Kamei, D, Jones Jr, L.E, Subramanian, V, Knuckley, B, Ebrahimi, P, Chumanevich, A.A, Luo, Y, Hashimoto, H, Shimizu, T, Sato, M, Hofseth, L.J, Thompson, P.R. 登録日 2011-07-13 公開日 2011-10-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Development of N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) and N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors J.Med.Chem., 54, 2011
1SK9	Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A, PHOSPHATE ION 著者 Liu, Q, Huang, Q, Lei, X.G, Hao, Q. 登録日 2004-03-04 公開日 2004-09-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics Structure, 12, 2004
3M2X	Carbonic Anhydrase II in complex with novel sulfonamide inhibitor 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, N-[(R)-[(3,4-dimethoxyphenyl)amino](phenoxy)methyl]sulfamide, ... 著者 Schulze Wischeler, J, Heine, A, Klebe, G. 登録日 2010-03-08 公開日 2011-05-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural investigation and inhibitor studies on Carbonic Anhydrase II To be Published
3PO6	Crystal structure of human carbonic anhydrase II with 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide 分子名称: (1R)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, (1S)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, ACETATE ION, ... 著者 Mader, P, Brynda, J, Gitto, R, Agnello, S, Ferro, S, De Luca, L, Vullo, D, Supuran, C.T, Chimirri, A. 登録日 2010-11-22 公開日 2011-04-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides. J.Med.Chem., 54, 2011
1AB0	C1G/V32D/F57H MUTANT OF MURINE ADIPOCYTE LIPID BINDING PROTEIN AT PH 4.5 分子名称: ADIPOCYTE LIPID BINDING PROTEIN 著者 Ory, J, Kane, C, Simpson, M, Banaszak, L, Bernlohr, D. 登録日 1997-01-30 公開日 1997-06-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biochemical and crystallographic analyses of a portal mutant of the adipocyte lipid-binding protein. J.Biol.Chem., 272, 1997
6RA8	Horse spleen apoferritin under 2 kBar of argon 分子名称: ARGON, CADMIUM ION, Ferritin light chain, ... 著者 Prange, T, Carpentier, P, Colloc'h, N. 登録日 2019-04-05 公開日 2020-05-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Labelling protein crystals by argon at 2 kbar To be published
4HNA	Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN 分子名称: ADENOSINE-5'-DIPHOSPHATE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Gigant, B, Knossow, M. 登録日 2012-10-19 公開日 2013-06-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structure of a kinesin-tubulin complex and implications for kinesin motility. Nat.Struct.Mol.Biol., 20, 2013

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