PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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6C63	Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin 分子名称: 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, POTASSIUM ION, RNA (32-MER), ... 著者 Trachman, R.J, Ferre-D'Amare, A.R. 登録日 2018-01-17 公開日 2018-08-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.900028 Å) 主引用文献 Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness. Biochemistry, 57, 2018
4Z25	Mimivirus R135 (residues 51-702) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase R135 著者 Klose, T, Rossmann, M.G. 登録日 2015-03-28 公開日 2015-06-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.339 Å) 主引用文献 A Mimivirus Enzyme that Participates in Viral Entry. Structure, 23, 2015
2PVK	Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 分子名称: 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha 著者 Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. 登録日 2007-05-09 公開日 2008-05-13 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
2PVY	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome. 分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION 著者 Chen, H, Mohammadi, M. 登録日 2007-05-10 公開日 2007-09-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
6BY7	Folding DNA into a lipid-conjugated nano-barrel for controlled reconstitution of membrane proteins 分子名称: DNA (26-MER), DNA (27-MER), DNA (29-MER), ... 著者 Dong, Y, Chen, S, Zhang, S, Sodroski, J, Yang, Z, Liu, D, Mao, Y. 登録日 2017-12-20 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Folding DNA into a Lipid-Conjugated Nanobarrel for Controlled Reconstitution of Membrane Proteins. Angew. Chem. Int. Ed. Engl., 57, 2018
4YXI	Human Carbonic Anhydrase II complexed with an inhibitor with a benzenesulfonamide group (2). 分子名称: 4-methylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Rechlin, C, Heine, A, Klebe, G. 登録日 2015-03-23 公開日 2016-02-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies. J.Med.Chem., 59, 2016
5TQJ	Crystal structure of response regulator receiver protein from Burkholderia phymatum 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Response regulator receiver protein 著者 Edwards, T.E, Dranow, D.M, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-10-24 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of response regulator receiver protein from Burkholderia phymatum To Be Published
2PZR	Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome 分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION 著者 Chen, H, Mohammadi, M. 登録日 2007-05-18 公開日 2007-09-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol.Cell, 27, 2007
5TR4	Structure of Ubiquitin activating enzyme (Uba1) in complex with ubiquitin and TAK-243 分子名称: Ubiquitin, Ubiquitin-activating enzyme E1 1, [(1~{R},2~{R},3~{S},4~{R})-2,3-bis(oxidanyl)-4-[[2-[3-(trifluoromethylsulfanyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl sulfamate 著者 Sintchak, M.D. 登録日 2016-10-25 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification and Characterization of a Small Molecule Inhibitor of the Ubiquitin Activating Enzyme (TAK-243) To be published
4YZ7	Crystal structure of Piratoxin I (PrTX-I) complexed to aristolochic acid 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 9-HYDROXY ARISTOLOCHIC ACID, Basic phospholipase A2 homolog piratoxin-1, ... 著者 Fernandes, C.A.H, Fontes, M.R.M. 登録日 2015-03-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9589 Å) 主引用文献 Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids. Plos One, 10, 2015
5UDW	LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with nickel 分子名称: Lactate racemization operon protein LarE, NICKEL (II) ION, PHOSPHATE ION, ... 著者 Fellner, M, Desguin, B, Hausinger, R.P, Hu, J. 登録日 2016-12-28 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.698 Å) 主引用文献 Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6BTC	SCCmec type IV LP1413 - nucleic acids binding protein 分子名称: LP1413 - SCCmec type IV-encoded DNA binding protein 著者 Rice, P.A, Mir-Sanchis, I. 登録日 2017-12-06 公開日 2018-07-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.1774075 Å) 主引用文献 Crystal Structure of an Unusual Single-Stranded DNA-Binding Protein Encoded by Staphylococcal Cassette Chromosome Elements. Structure, 26, 2018
5UEI	Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo) 分子名称: CHLORIDE ION, GLYCEROL, O13 著者 Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A. 登録日 2017-01-02 公開日 2017-10-18 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
4YZR	Bacillus subtilis 168 Bacillaene Polyketide Synthase (PKS) Cytochrome P450 PksS 分子名称: HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE, Polyketide biosynthesis cytochrome P450 PksS 著者 Race, P.R, Zulkepli, A.Z, Anderson, R.J.L. 登録日 2015-03-25 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Bacillus subtilis 168 Bacillaene Polyketide Synthase (PKS) Cytochrome P450 PksS To Be Published
4Z0L	The murine cyclooxygenase-2 complexed with a nido-dicarbaborate-containing indomethacin derivative 分子名称: (R)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate, (S)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Xu, S, Neumann, W, Banerjee, S, Hey-Hawkins, E, Marnett, L.J. 登録日 2015-03-26 公開日 2015-06-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2. Chemmedchem, 11, 2016
6C5A	Human UDP-Glucose Dehydrogenase with UDP- Glc and NADH bound 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, UDP-glucose 6-dehydrogenase, ... 著者 Gross, P.G, Fallah, J, Wood, Z.A. 登録日 2018-01-15 公開日 2019-01-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The A225L Substitution of hUGDH alters structure and function To Be Published
6C6D	20mer crystal structure of CC chemokine 5 (CCL5) 分子名称: C-C motif chemokine 5 著者 Liang, W.G, Tang, W.J. 登録日 2018-01-18 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 20mer crystal structure of CC chemokine 5 (CCL5) To Be Published
6BVR	Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION 著者 Yang, Y, Liu, F, Liu, A. 登録日 2017-12-13 公開日 2018-06-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities. J. Biol. Chem., 293, 2018
4Z42	Crystal structure of urease from Yersinia enterocolitica 分子名称: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ... 著者 Studer, G, Jakob, R.P, Mahi, M.A, Wiesand, U, Schwede, T, Maier, T. 登録日 2015-04-01 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystal structure of urease from Yersinia enterocolitica To Be Published
2Q1W	Crystal structure of the Bordetella bronchiseptica enzyme WbmH in complex with NAD+ 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative nucleotide sugar epimerase/ dehydratase 著者 King, J.D, Harmer, N.J, Maskell, D.J, Blundell, T.L. 登録日 2007-05-25 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Predicting protein function from structure--the roles of short-chain dehydrogenase/reductase enzymes in Bordetella O-antigen biosynthesis. J.Mol.Biol., 374, 2007
5TVC	Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312) 分子名称: (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine, PENTAETHYLENE GLYCOL, SULFATE ION, ... 著者 Bobango, J, Wu, J, Talley, I.T, Talley, T.T. 登録日 2016-11-08 公開日 2016-11-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.926 Å) 主引用文献 Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312) To Be Published
4ZCV	Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P212121 form 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... 著者 Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. 登録日 2015-04-16 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier. Biochim.Biophys.Acta, 1847, 2015
4Z6W	Structure of H200N variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-nitrocatechol at 1.57 Ang resolution 分子名称: 4-NITROCATECHOL, CALCIUM ION, CHLORIDE ION, ... 著者 Kovaleva, E.G, Lipscomb, J.D. 登録日 2015-04-06 公開日 2015-08-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200. Biochemistry, 54, 2015
6BL3	Crystal Complex of Cyclooxygenase-2 with indomethacin-butyldiamine-dansyl conjugate 分子名称: 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)butyl]acetamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Xu, S, Uddin, M.J, Banerjee, S, Marnett, L.J. 登録日 2017-11-09 公開日 2018-11-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.217 Å) 主引用文献 Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. J.Biol.Chem., 294, 2019
2Q47	Ensemble refinement of the protein crystal structure of a putative phosphoprotein phosphatase from Arabidopsis thaliana gene At1g05000 分子名称: Probable tyrosine-protein phosphatase At1g05000, SULFATE ION 著者 Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2007-05-31 公開日 2007-06-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007

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