Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2OHU
DownloadVisualize
BU of 2ohu by Molmil
X-ray crystal structure of beta secretase complexed with compound 8b
分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ...
著者Patel, S.
登録日2007-01-10
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
J.Med.Chem., 50, 2007
2NRO
DownloadVisualize
BU of 2nro by Molmil
MoeA K279Q
分子名称: Molybdopterin biosynthesis protein moeA
著者Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V.
登録日2006-11-02
公開日2007-01-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
Biochemistry, 46, 2007
2OC2
DownloadVisualize
BU of 2oc2 by Molmil
Structure of testis ACE with RXPA380
分子名称: Angiotensin-converting enzyme, somatic isoform, CHLORIDE ION, ...
著者Corradi, H.R, Anthony, C.S, Schwager, S.L, Redelinghuys, P, Georgiadis, D, Dive, V, Acharya, K.R, Sturrock, E.D.
登録日2006-12-20
公開日2007-05-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380.
Biochemistry, 46, 2007
6ZQT
DownloadVisualize
BU of 6zqt by Molmil
Crystal structure of the RLIP76 Ral binding domain mutant (E427H/Q433L/K440R) in complex with RalB-GMPPNP
分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Hurd, C, Brear, P, Revell, J, Ross, S, Mott, H, Owen, D.
登録日2020-07-10
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
J.Biol.Chem., 296, 2020
2OHQ
DownloadVisualize
BU of 2ohq by Molmil
X-ray crystal structure of beta secretase complexed with compound 4
分子名称: 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE, Beta-secretase 1, DIMETHYL SULFOXIDE, ...
著者Patel, S.
登録日2007-01-10
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
J.Med.Chem., 50, 2007
2OHT
DownloadVisualize
BU of 2oht by Molmil
X-ray crystal structure of beta secretase complexed with compound 7
分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ...
著者Patel, S.
登録日2007-01-10
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
J.Med.Chem., 50, 2007
2ONL
DownloadVisualize
BU of 2onl by Molmil
Crystal Structure of the p38a-MAPKAP kinase 2 Heterodimer
分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14
著者Ter Haar, E.
登録日2007-01-24
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer.
J.Biol.Chem., 282, 2007
2ONS
DownloadVisualize
BU of 2ons by Molmil
Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate
分子名称: MAGNESIUM ION, NITRATE ION, TUNGSTATE(VI)ION, ...
著者Hollenstein, K, Frei, D.C, Locher, K.P.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of an ABC transporter in complex with its binding protein.
Nature, 446, 2007
2OQ1
DownloadVisualize
BU of 2oq1 by Molmil
Tandem SH2 domains of ZAP-70 with 19-mer zeta1 peptide
分子名称: LEAD (II) ION, T-cell surface glycoprotein CD3 zeta chain, Tyrosine-protein kinase ZAP-70
著者Hatada, M.H, Laird, E.R, Green, J, Morgenstern, J, Ram, M.K.
登録日2007-01-30
公開日2007-03-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for the interaction of ZAP-70 with the T-cell receptor
Nature, 377, 1995
2ONR
DownloadVisualize
BU of 2onr by Molmil
Crystal structure of A. fulgidus periplasmic binding protein ModA with bound molybdate
分子名称: MAGNESIUM ION, MOLYBDATE ION, NITRATE ION, ...
著者Hollenstein, K, Frei, D.C, Locher, K.P.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of an ABC transporter in complex with its binding protein.
Nature, 446, 2007
2P6U
DownloadVisualize
BU of 2p6u by Molmil
Apo structure of the Hel308 superfamily 2 helicase
分子名称: PHOSPHATE ION, afuHEL308 HELICASE
著者Buettner, K, Nehring, S, Hopfner, K.P.
登録日2007-03-19
公開日2007-06-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Structural basis for DNA duplex separation by a superfamily-2 helicase.
Nat.Struct.Mol.Biol., 14, 2007
2PAV
DownloadVisualize
BU of 2pav by Molmil
Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Ferron, F, Rebowski, G, Dominguez, R.
登録日2007-03-27
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.
Embo J., 26, 2007
2PI0
DownloadVisualize
BU of 2pi0 by Molmil
Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer
分子名称: Interferon regulatory factor 3, PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2
著者Escalante, C.R, Nistal-Villan, E, Leyi, S, Garcia-Sastre, A, Aggarwal, A.K.
登録日2007-04-12
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer.
Mol.Cell, 26, 2007
2PFD
DownloadVisualize
BU of 2pfd by Molmil
Anisotropically refined structure of FTCD
分子名称: Formimidoyltransferase-cyclodeaminase
著者Poon, B.K, Chen, X, Lu, M, Quiocho, F.A, Wang, Q, Ma, J.
登録日2007-04-04
公開日2007-04-24
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Anisotropically refined structure of FTCD
To be Published
6V8K
DownloadVisualize
BU of 6v8k by Molmil
Crystal structure of the p300 acetyltransferase domain with peptide-competitive inhibitor 2
分子名称: 1-(2-methyl-1H-indol-3-yl)-2-[(2R)-2-methylpiperidin-1-yl]ethan-1-one, COENZYME A, DIMETHYL SULFOXIDE, ...
著者Gardberg, A.S.
登録日2019-12-11
公開日2020-04-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors.
Chemmedchem, 15, 2020
2PKS
DownloadVisualize
BU of 2pks by Molmil
Thrombin in complex with inhibitor
分子名称: 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE, Hirudin, SODIUM ION, ...
著者Xue, Y.
登録日2007-04-18
公開日2008-04-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold.
Org.Biomol.Chem., 5, 2007
2PNL
DownloadVisualize
BU of 2pnl by Molmil
Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1
分子名称: GUANIDINE, Protease VP4
著者Paetzel, M, Lee, J, Feldman, A.R, Delmas, B.
登録日2007-04-24
公開日2007-06-05
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.
J.Biol.Chem., 282, 2007
2PFZ
DownloadVisualize
BU of 2pfz by Molmil
Crystal structure of DctP6, a Bordetella pertussis extracytoplasmic solute receptor binding pyroglutamic acid
分子名称: PYROGLUTAMIC ACID, Putative exported protein
著者Rucktooa, P.
登録日2007-04-06
公開日2007-06-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of two Bordetella pertussis Periplasmic Receptors Contribute to Defining a Novel Pyroglutamic Acid Binding DctP Subfamily.
J.Mol.Biol., 370, 2007
2PUQ
DownloadVisualize
BU of 2puq by Molmil
Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
分子名称: CALCIUM ION, Coagulation factor VII, TRP-TYR-THR-ARG CHLOROMETHYLKETONE INHIBITOR, ...
著者Bjelke, J.R, Rasmussen, H.B.
登録日2007-05-09
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa
Biochem.J., 405, 2007
2O6C
DownloadVisualize
BU of 2o6c by Molmil
Structure of selenomethionyl rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2OB2
DownloadVisualize
BU of 2ob2 by Molmil
ppm1 in the absence of 1,8-ANS (cf 1JD)
分子名称: GLYCEROL, Leucine carboxyl methyltransferase 1, PHOSPHATE ION, ...
著者Groves, M.R, Mueller, I.B, Kreplin, X, Mueller-Dieckmann, J.
登録日2006-12-18
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye.
Acta Crystallogr.,Sect.D, 63, 2007
2OCX
DownloadVisualize
BU of 2ocx by Molmil
Crystal structure of Se-Met fucosyltransferase NodZ from Bradyrhizobium
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nodulation fucosyltransferase NodZ, PHOSPHATE ION
著者Brzezinski, K, Stepkowski, T, Panjikar, S, Bujacz, G, Jaskolski, M.
登録日2006-12-21
公開日2007-11-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor.
Acta Biochim.Pol., 54, 2007
2O1X
DownloadVisualize
BU of 2o1x by Molmil
1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Deinococcus radiodurans
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Xiang, S, Usunow, G, Lange, G, Busch, M, Tong, L.
登録日2006-11-29
公開日2006-12-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis.
J.Biol.Chem., 282, 2007
2O4P
DownloadVisualize
BU of 2o4p by Molmil
Crystal Structure of HIV-1 Protease (Q7K) in Complex with Tipranavir
分子名称: GLYCEROL, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE, protease
著者Kang, L.W, Armstrong, A.A, Muzammil, S, Jakalian, A, Bonneau, P.R, Schmelmer, V, Freire, E, Amzel, L.M.
登録日2006-12-04
公開日2006-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations.
J.Virol., 81, 2007
6WUU
DownloadVisualize
BU of 6wuu by Molmil
Crystal structure of the SARS CoV-2 Papain-like protease in complex with peptide inhibitor VIR250
分子名称: MAGNESIUM ION, Non-structural protein 3, VIR250, ...
著者Lv, Z, Olsen, S.K.
登録日2020-05-05
公開日2020-05-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.
Sci Adv, 6, 2020

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon